CANCER GENOMICS

The expression and clinical significance of serum exosomes miR-122 and miR-874 in patients with colorectal cancer

Expression of APOC3 in human colon cancer, the clinical and therapeutic value

Characterizing Circulating Tumor Cell and containing Cancer Stem Cell Heterogeneity in Pancreatic Adenocarcinoma: A Single Cell Perspective

Comparative analysis of genomic and clinicopathologic characteristics between multifocal and unifocal breast cancer patients by whole-exome sequencing

Spatiotemporal multi-omics uncover tumor ecosystem dynamics driving metastatic colonization

Machine learning-derived mutational signatures reveal distinct DNA repair pathway dysregulation and clinical outcomes in BRCA1/2 ovarian cancer

Single-cell analysis reveals tumor-driven immune microenvironment reprogramming that promotes lung adenocarcinoma metastasis.

Studying genomic evolution in colonic cell line models of mismatch repair deficiency.

CRISPR-Cas9 knock-out screening of lncRNAs highlights new therapeutic targets for cancer treatment

FUNCTIONAL EXPLORATION THE MOLECULAR MECHANISM OF THE REGULATION FACTORS WHICH ARE RELATED TO THE TUMORIGEN-ESIS AND PROGNOSIS OF COLORECTAL CANCER

Non-canonical ORF Translation in Neuroblastoma: A New Source of Therapeutic Targets?

A Cost-Effective Droplet-Based Single-Cell Total RNA Sequencing Technology Reveals Transcriptional Heterogeneity in Drug-Tolerant Cancer Cells

Spatial transcriptomics in precancerous lesions of the colorectum

Cardiac metastasis: From spatial transcriptomics to targeted therapy

Identification of therapeutic targets and dependencies in ZNF703-amplified breast cancer

Recurrent endocervical polyps harbor UBE2A p.(Arg6Trp) mutation

Core2Edge: A Human Glioblastoma Organoid and Brain Slice Co-Culture Model Capturing Tumor Infiltration and Transcriptional Heterogeneity from Core to Single-Cell Dispersion

Deciphering the Timing of Somatic Driver Mutations in Early-Onset Breast Cancer

Metabolic relevance of p53 hotspot mutations in hepatocellular carcinoma

Exploring EGLN1 as a therapeutic target for KRAS mutated lung cancer: insights into mitochondrial modulation

Decoding the Molecular Complexity of HCC: Clonal Diversity, Functional States, and Tumor-Stroma Crosstalk

Single-cell sequencing analysis highlights the transdifferentiation potential of cancer cells in a neuroblastoma cell line

Same-cell spatial transcriptomics and proteomics expression at single-cell resolution to decipher melanoma cell state heterogeneity and relationships with the inflammatory microenvironment in metastas

Integrated multi-omics analysis identifies sex differences in muscle-invasive bladder cancer

Comprehensive genomic profiling and RNA-seq analysis reveal distinct genomic and transcriptomic signatures associated with treatment response in metastatic colorectal cancer (mCRC) patients (pts) enrolled in the NIVACOR trial

Novel replication stress signature predicts non-homologous end-joining association mediated by the MutSα complex

Glucocorticoid receptor as a prognostic factor in triple-negative breast cancer correlates with migratory signature at a single-cell level

Spatial profiling of matched adnexal and omental tumors in high-grade serous carcinoma

Phenotypic and genomic characterisation of single micronuclei

Unraveling the influence of risk factors on tumour evolution in clear cell renal cell carcinoma

Is it the T-cell to Macrophage Ration that matters for treatment in TNBC

Investigating the impact of PRUNE2 deregulation on prostate cancer

Unveiling plasma cell–tumor cross-talk to boost immunotherapy in microsatellite-stable colon cancer

Spatial Multiomics Reveals T-cell Activation and Exhaustion States in the Tumor Microenvironment 

Decoding the Complexity of Prostate Cancer Evolution: Uncovering Heterogeneous Cell States by Integrative Approaches

Inhibition of the heat shock response enhances modulated electrohyperthermia effects in triple negative breast cancer mouse model

Prevalence of Chromosomal Alterations in Acute Leukemias: A Descriptive Analysis in the Colombian Population

Targeting Aurora Kinase A in Breast Cancer Brain Metastasis

Unraveling the role of LKB1 mutations in Non-Small Cell Lung Cancer brain metastasis formation

Genomic profiling of tumour and liquid biopsy melanoma samples with targeted next-generation sequencing

STAG2 mutations in the normal colon induce upregulation of oncogenic pathways in neighbouring wildtype cells

Genome-wide CRISPR screen identifies RAB14 as a new target for gastric cancer treatment

Beyond BRAF V600E: Revealing the Hidden Clinical Relevance of Uncharacterized BRAF Variants

Intra-Tumour Heterogeneity in Cutaneous Squamous Cell Carcinoma Assessed by Spatial Transcriptomics

The landscape of copy number intra-tumour heterogeneity in breast cancer and its impact on the tumour ecosystem

Microhomology-Driven Genomic Alterations in Ovarian Cancer

Mapping Therapeutic Opportunities in LUSC Through Targeted Compound Screening

Exposing G2/M Checkpoint Vulnerabilities: BUB1B and BUB3 as Essential Dependencies in Malignant Pleural Mesothelioma

Deciphering oncogenic gene regulatory mechanisms at nucleotide resolution using precision genome editing

Common Genetic Dependencies of Sonic Hedgehog Medulloblastoma (SHH-MB) variants are Regulated by the Non-Malignant Microenvironment

GEM-X Flex: Scalable and cost-effective whole transcriptome single cell analysis for cancer marker detection from FFPE tissue section slides

Extensive spatial heterogeneity of transcript variants in localised prostate cancer

Spatial transcriptomic insights into the influence of cancer-associated fibroblast profiles in oral cancer spheroids

Optimizing low input and high-throughput cell fixation for single-cell RNA sequencing with combinatorial barcoding

Heterogenous fusion transcript landscape in multifocal primary prostate cancer

Unraveling chemoresistance in breast cancer through circulating miRNAs in liquid biopsy

The TP53:AHR genetic interaction regulates MAGE:TRIM28 activity to prevent cellular transformation

Sex-Dependent Transcriptional Gene Expression in Urothelial Bladder Cancer

Spatial Transcriptomics for characterising pathologic response to FOLFOX regimen in colorectal Liver Metastases

Genomic Analysis of PARP Inhibitor Response in High-Grade Serous Ovarian Cancer: Insights from Whole Genome Sequencing