CANCER GENOMICS

17/06/2025 10:45 20:00

Poster and Exhibition Hall

Time	Session

10:45 20:00	The expression and clinical significance of serum exosomes miR-122 and miR-874 in patients with colorectal cancer P-219 EACR25-0024 Yong Wang Poster Presenter China	Expression of APOC3 in human colon cancer, the clinical and therapeutic value P-220 EACR25-0190 CAI WANG Poster Presenter United Kingdom	Characterizing Circulating Tumor Cell and containing Cancer Stem Cell Heterogeneity in Pancreatic Adenocarcinoma: A Single Cell Perspective P-221 EACR25-0270 Berina Sabanovic Poster Presenter Italy	Comparative analysis of genomic and clinicopathologic characteristics between multifocal and unifocal breast cancer patients by whole-exome sequencing P-222 EACR25-0314 chungyeul kim Poster Presenter Korea (Republic of)	Spatiotemporal multi-omics uncover tumor ecosystem dynamics driving metastatic colonization P-223 EACR25-0336 LIANG WU Poster Presenter China	Machine learning-derived mutational signatures reveal distinct DNA repair pathway dysregulation and clinical outcomes in BRCA1/2 ovarian cancer P-224 EACR25-0382 Ionut-Gabriel Funingana Poster Presenter United Kingdom	Single-cell analysis reveals tumor-driven immune microenvironment reprogramming that promotes lung adenocarcinoma metastasis. P-225 EACR25-0388 huijuan zhang Poster Presenter United Kingdom	Studying genomic evolution in colonic cell line models of mismatch repair deficiency. P-226 EACR25-0494 Zofia Piszka Poster Presenter United Kingdom	CRISPR-Cas9 knock-out screening of lncRNAs highlights new therapeutic targets for cancer treatment P-227 EACR25-0498 Ottavio Croci Poster Presenter Italy	FUNCTIONAL EXPLORATION THE MOLECULAR MECHANISM OF THE REGULATION FACTORS WHICH ARE RELATED TO THE TUMORIGEN-ESIS AND PROGNOSIS OF COLORECTAL CANCER P-228 EACR25-0522 LIU WEI HUAN Poster Presenter Taiwan	Non-canonical ORF Translation in Neuroblastoma: A New Source of Therapeutic Targets? P-229 EACR25-0576 Martina Jovancheva Poster Presenter Netherlands	Spatial transcriptomics in precancerous lesions of the colorectum P-231 EACR25-0638 Ma Poster Presenter Sweden	Cardiac metastasis: From spatial transcriptomics to targeted therapy P-232 EACR25-0674 Daniela Lorizio Poster Presenter Italy	Identification of therapeutic targets and dependencies in ZNF703-amplified breast cancer P-233 EACR25-0768 Allan Lui Poster Presenter United Kingdom	Recurrent endocervical polyps harbor UBE2A p.(Arg6Trp) mutation P-234 EACR25-0832 Siiri Kev Poster Presenter Finland	Core2Edge: A Human Glioblastoma Organoid and Brain Slice Co-Culture Model Capturing Tumor Infiltration and Transcriptional Heterogeneity from Core to Single-Cell Dispersion P-235 EACR25-0848 Ahmad Melhem Poster Presenter Germany	Deciphering the Timing of Somatic Driver Mutations in Early-Onset Breast Cancer P-236 EACR25-0856 Bhin Jinhyuk Poster Presenter Korea (Republic of)	Metabolic relevance of p53 hotspot mutations in hepatocellular carcinoma P-237 EACR25-0950 Jelena Krstic Poster Presenter Austria	Exploring EGLN1 as a therapeutic target for KRAS mutated lung cancer: insights into mitochondrial modulation P-238 EACR25-0986 Alessandra Grieco Poster Presenter Italy	Decoding the Molecular Complexity of HCC: Clonal Diversity, Functional States, and Tumor-Stroma Crosstalk P-239 EACR25-1010 INES SIMEONE Poster Presenter Italy	Single-cell sequencing analysis highlights the transdifferentiation potential of cancer cells in a neuroblastoma cell line P-240 EACR25-1076 Tomanelli Michele Poster Presenter Italy	Dual mutations in ARID1A and PIK3CA drive aggressiveness and drug resistance in estrogen receptor-positive breast cancer P-278A EACR25-1150 Almog Bachar Poster Presenter Israel	Same-cell spatial transcriptomics and proteomics expression at single-cell resolution to decipher melanoma cell state heterogeneity and relationships with the inflammatory microenvironment in metastas P-241 EACR25-1164 Madhavi Dipak Andhari Poster Presenter Belgium	Integrated multi-omics analysis identifies sex differences in muscle-invasive bladder cancer P-242 EACR25-1200 Jung Min Sung Poster Presenter Korea (Republic of)	Comprehensive genomic profiling and RNA-seq analysis reveal distinct genomic and transcriptomic signatures associated with treatment response in metastatic colorectal cancer (mCRC) patients (pts) enrolled in the NIVACOR trial P-243 EACR25-1254 Riziero Esposito Abate Poster Presenter Italy	Novel replication stress signature predicts non-homologous end-joining association mediated by the MutSα complex P-244 EACR25-1262 Philipp Jungk Poster Presenter Germany	Glucocorticoid receptor as a prognostic factor in triple-negative breast cancer correlates with migratory signature at a single-cell level P-245 EACR25-1290 Attila Pat Poster Presenter Hungary	Spatial profiling of matched adnexal and omental tumors in high-grade serous carcinoma P-246 EACR25-1328 Niina Anneli Aho Poster Presenter Finland	Phenotypic and genomic characterisation of single micronuclei P-247 EACR25-1334 Jovanna Maharaj Poster Presenter United Kingdom	Unraveling the influence of risk factors on tumour evolution in clear cell renal cell carcinoma P-248 EACR25-1340 Olivia Dove Poster Presenter Spain	Is it the T-cell to Macrophage Ration that matters for treatment in TNBC P-249 EACR25-1388 Madhura Kulkarni Poster Presenter India	Investigating the impact of PRUNE2 deregulation on prostate cancer P-250 EACR25-1392 Andreia Brand Poster Presenter Portugal	Unveiling plasma cell–tumor cross-talk to boost immunotherapy in microsatellite-stable colon cancer P-251 EACR25-1436 Belen Martinez Castedo Poster Presenter Spain	Spatial Multiomics Reveals T-cell Activation and Exhaustion States in the Tumor Microenvironment  P-252 EACR25-1444 Mathilde Busson Poster Presenter United Kingdom	Mutational Signature Profiling in KRAS Mutant Lung Adenocarcinoma: Variant-Specific Associations and Prognostic Implications P-264 EACR25-1448 Laura Woodhouse Poster Presenter United Kingdom	Decoding the Complexity of Prostate Cancer Evolution: Uncovering Heterogeneous Cell States by Integrative Approaches P-253 EACR25-1584 Giada Andrea Cassanmagnago Poster Presenter Switzerland	Inhibition of the heat shock response enhances modulated electrohyperthermia effects in triple negative breast cancer mouse model P-254 EACR25-1672 Peter Hamar Poster Presenter Hungary	Prevalence of Chromosomal Alterations in Acute Leukemias: A Descriptive Analysis in the Colombian Population P-255 EACR25-1694 Rafael Parra-Medina Poster Presenter Colombia	Targeting Aurora Kinase A in Breast Cancer Brain Metastasis P-256 EACR25-1740 Damir Vareslija Poster Presenter Ireland	Unraveling the role of LKB1 mutations in Non-Small Cell Lung Cancer brain metastasis formation P-257 EACR25-1768 Laureen Sarah Goodman Poster Presenter Israel	Genomic profiling of tumour and liquid biopsy melanoma samples with targeted next-generation sequencing P-258 EACR25-1774 Magdalena Olbryt Poster Presenter Poland	STAG2 mutations in the normal colon induce upregulation of oncogenic pathways in neighbouring wildtype cells P-259 EACR25-1830 Dedrick Kok Hong Chan Poster Presenter Singapore	Genome-wide CRISPR screen identifies RAB14 as a new target for gastric cancer treatment P-260 EACR25-1840 Ana Catarina Nunes Poster Presenter Portugal	Beyond BRAF V600E: Revealing the Hidden Clinical Relevance of Uncharacterized BRAF Variants P-261 EACR25-1892 Dries Vanisterbecq Poster Presenter Belgium	Intra-Tumour Heterogeneity in Cutaneous Squamous Cell Carcinoma Assessed by Spatial Transcriptomics P-262 EACR25-1894 Paranita Ferronika Poster Presenter	The landscape of copy number intra-tumour heterogeneity in breast cancer and its impact on the tumour ecosystem P-263 EACR25-1942 Callari Maurizio Poster Presenter Italy	Microhomology-Driven Genomic Alterations in Ovarian Cancer P-912 EACR25-2024 Daria Kostka Poster Presenter Poland	Mapping Therapeutic Opportunities in LUSC Through Targeted Compound Screening P-265 EACR25-2038 Andrada Teodora Iovi__ Poster Presenter Romania	Exposing G2/M Checkpoint Vulnerabilities: BUB1B and BUB3 as Essential Dependencies in Malignant Pleural Mesothelioma P-266 EACR25-2106 Ebru K Poster Presenter Turkey	Deciphering oncogenic gene regulatory mechanisms at nucleotide resolution using precision genome editing P-267 EACR25-2186 Juuli Hietarinne Poster Presenter Finland	Common Genetic Dependencies of Sonic Hedgehog Medulloblastoma (SHH-MB) variants are Regulated by the Non-Malignant Microenvironment P-268 EACR25-2252 John Jacob Poster Presenter United Kingdom	GEM-X Flex: Scalable and cost-effective whole transcriptome single cell analysis for cancer marker detection from FFPE tissue section slides P-269 EACR25-2348 Tingsheng Yu Drennon Poster Presenter United States	Advancing tumor characterization and immune phenotyping through multiomic in situ profiling of RNA and proteins P-904 EACR25-2350	Extensive spatial heterogeneity of transcript variants in localised prostate cancer P-270 EACR25-2380 Susanne G. Kidd Poster Presenter Norway	Spatial transcriptomic insights into the influence of cancer-associated fibroblast profiles in oral cancer spheroids P-271 EACR25-2382 Leonardo Rocha Poster Presenter Brazil	Optimizing low input and high-throughput cell fixation for single-cell RNA sequencing with combinatorial barcoding P-272 EACR25-2446 Gokhan Demirkan Poster Presenter United States	Heterogenous fusion transcript landscape in multifocal primary prostate cancer P-273 EACR25-2452 Ane Stranger Poster Presenter Norway	Unraveling chemoresistance in breast cancer through circulating miRNAs in liquid biopsy P-274 EACR25-2468 Romero Sandra Poster Presenter Mexico	The TP53:AHR genetic interaction regulates MAGE:TRIM28 activity to prevent cellular transformation P-275 EACR25-2494 Dorothea Maneta Poster Presenter Germany	Sex-Dependent Transcriptional Gene Expression in Urothelial Bladder Cancer P-276 EACR25-2496 Ayse Nur Myumyun Poster Presenter United Kingdom	Spatial Transcriptomics for characterising pathologic response to FOLFOX regimen in colorectal Liver Metastases P-277 EACR25-2564 Natalia Molina Poster Presenter Spain	Genomic Analysis of PARP Inhibitor Response in High-Grade Serous Ovarian Cancer: Insights from Whole Genome Sequencing P-278 EACR25-2592 Hyerim Eum Poster Presenter Korea (Republic of)