DRUG RESISTANCE

17/06/2025 10:45 20:00

Poster and Exhibition Hall

Time	Session

10:45 20:00	Three- dimensional (3D) Cancer Microenvironment that Confers Chemoresistance to DNA Damaging Drug P-291 EACR25-0208 Jue Shi Poster Presenter Hong Kong, China	Targeted Delivery of NVPBEZ235 conjugated to gold nanoparticles for Overcoming Gemcitabine Resistance in Triple-Negative Breast Cancer P-292 EACR25-0218 _uranur Ayvaz Poster Presenter Turkey	In Silico Identification of Common Pre-existing Resistance Mechanisms to EGFR Inhibitors in Colorectal Cancer P-293 EACR25-0278 Carlos Fernandez-Lozano Poster Presenter Spain	A newly discovered mTOR-STAT3 pathway regulates calcium release and calcium-mediated apoptosis at the ER in Triple Negative Breast Cancer P-295 EACR25-0456 Daniele Viavattene Poster Presenter Italy	Evaluate the potential sensitization effect and underlying mechanism of tyrosine kinase inhibitor on cisplatin resistance oral squamous cell carcinoma P-296 EACR25-0566 Ying-Tzu Chen Poster Presenter Taiwan	Study of long non-coding RNAs in resistance to KRAS G12C inhibitors in lung cancers P-297 EACR25-0574 Thomas PAPAZYAN Poster Presenter France	Targeting the Non-Homologous End-Joining Pathway Sensitizes MDM2-Amplified Liposarcoma to Doxorubicin-Induced Senescence in a p53-dependent Manner P-298 EACR25-0592 Thijs Jalving Poster Presenter Netherlands	Regulation of FOXK2 by AKT in breast cancer cells: Serine 398 as a novel potential phosphorylation site P-299 EACR25-0598 Luciana da Torre Carneiro Poster Presenter Brazil	FOXK2 transcription factor in cancer: expression, function and potential as a biomarker P-300 EACR25-0600 Renata Ivo Vasconcelos Poster Presenter Brazil	Targeting low fidelity polymerases to prevent acquired resistance mutations to EGFR-targeted therapy in lung cancer. P-301 EACR25-0764 Marieke Van Daele Poster Presenter Israel	Inhibition of the extracellular signal-regulated kinase 5 (ERK5) increases EGFR expression and its nuclear localization in HCC, generating new targeting opportunities P-302 EACR25-0984 Alessio Menconi Poster Presenter Italy	mTORC1 Fuels Resistance but Unlocks Metabolic Kill-Switch in PI3K-Mutant Breast Cancer P-303 EACR25-1238 Alina Stroh Poster Presenter Germany	Assessment of two new ROS1+ NSCLC patient-derived cell lines as in vitro models for TKI resistance studies P-304 EACR25-1298 Christa Dijkhuizen Poster Presenter Netherlands	Discovery of Molecular and Epigenetic Candidates Underlying Chemoresistance of Colorectal Cancer P-305 EACR25-1344 Saba Selvi Poster Presenter Czech Republic	The mechanism of PPARα-mediated cholesterol metabolism in regulating paclitaxel resistance in ovarian cancer cells P-306 EACR25-1350 Mingzhuo Chen Poster Presenter China	AP-1 transcription factor is a targetable mediator of osimertinib resistance in EGFR-mutant non-small cell lung cancer P-307 EACR25-1424 Sude Eris Poster Presenter Turkey	Overactivation of oncogenic signaling steers cancer cells toward less malignant phenotypes P-308 EACR25-1446 Chrysa Papagianni Poster Presenter Netherlands	CIC: The Master Regulator of Resistance to MAPK Pathway Inhibition P-309 EACR25-1480 Joao Neto Poster Presenter Netherlands	Unlocking New Therapies: Targeting GSDMB Overexpression in HER2-Positive Tumors P-310 EACR25-1572 Carmen Ramos Nebot Poster Presenter Spain	FGFR signaling as a key mediator of resistance to alpelisib/fulvestrant combination in PIK3CA-mutant luminal A breast cancer P-311 EACR25-1592 Melda Ozge Oguz Poster Presenter Turkey	Targeting Ferroptosis to Enhance the Efficacy of BRAF/MEK Inhibitors in Overcoming Resistance in Melanoma P-312 EACR25-1612 Juan Antonio Fafian Labora Poster Presenter Spain	Investigation of the expression of drug resistance genes after Sorafenib administration P-313 EACR25-1622 IPEK ECE KOCKAR Poster Presenter Turkey	Targeting CCL19/21-CCR7 axis to overcome resistance to ALK inhibitors in ALK+ lymphoma P-314 EACR25-1644 Mariapia Russo Poster Presenter Italy	T-cell receptor (TCR) diversity in buffy coat samples from blood of ovarian, vulvar squamous cell and cervical cancer patients P-294 EACR25-1656 Corinna Keup Poster Presenter Germany	Genomic Instability and Epigenomic Dysregulation as Hallmarks of mCRC Therapy Resistance — Findings from Broad ctDNA Molecular Profiling (METACC) P-315 EACR25-1664 Camblor Daniel G. Poster Presenter Spain	Exploring potential strategies overcoming the PARPi resistance in the Olaparib induced MDA-MB-436 resistant model P-316 EACR25-1698 FEIFEI FEI FAN Poster Presenter China	BMI1 as a therapeutic target to overcome chemoresistance in high-grade serous ovarian cancer P-317 EACR25-1980 Sadia Zafar Poster Presenter Finland	Identification of microRNAs and their target genes associated with acquired resistance of primary melanoma cells to targeted therapy P-318 EACR25-2034 Ignacija Vla_i_ Poster Presenter Croatia	Impact of Mechanical Stress and Confinement on the Alteration of Protein Expression and Emergence of Time-Dependent Resistance to Cisplatin P-319 EACR25-2042 Yasmin Antonelli Poster Presenter Germany	Uncovering Transcriptional Signatures of Differential Drug Response in Archetypical Malignant States in Metastatic Breast Cancer (MBC) P-320 EACR25-2062 Hodaya Haimov Poster Presenter Israel	Overcoming P-glycoprotein-mediated resistance in tumor cells through copolymers for cytotoxic drug delivery P-321 EACR25-2102 Milada _ Poster Presenter Czech Republic	Dual targeting BRD4-CDK9 transcriptional complex as a potent therapeutic strategy in glioblastoma P-322 EACR25-2108 Raquel L Poster Presenter Spain	Unraveling mechanisms of CDK4/6 inhibitors resistance in metastatic breast cancer P-323 EACR25-2112 Irina Suheila Fonseca Poster Presenter Spain	Immune infiltration is associated with favorable response to neoadjuvant chemotherapy and carboplatin in hormone receptor positive and triple negative breast cancer P-324 EACR25-2246 Eivind Valen Egeland Poster Presenter Norway	Inhibition of the RNA-binding protein HuR reduces cell proliferation and promotes apoptosis in EGFR-TKI resistant NSCLC cells P-325 EACR25-2270 Annarita Cascone Poster Presenter Italy	Targeting PI3K/AKT Pathway Dysregulation in Triple-Negative Breast Cancer: Overcoming Alpelisib Resistance through Dual Inhibition P-326 EACR25-2322 Grace Colley Poster Presenter Ireland	Endothelial-Derived CAFs Drive Chemoresistance via ERCC1-IL-17A Axis: A Novel Therapeutic Target in Tumour Microenvironment P-327 EACR25-2390 Katarzyna Sobierajska Poster Presenter Poland	miR-181a-5p and Caveolin-1 Express Inversely in HCC and Augment the Aggressive Phenotype of Sorafenib-Resistant HCC Cells P-328 EACR25-2410 Ezgi Bagirsakci Poster Presenter Turkey	Overcoming Taxane Resistance Through PRMT5 Inhibition: Targeting Epigenetic Mechanisms P-329 EACR25-2458 Ezgi Karyemez Poster Presenter Turkey	Unraveling tumor intrinsic responses: IFN-gamma predicts clinical immunotherapy efficacy and exclusively triggers apoptosis in solid tumors while sparing hematologic malignancies P-330 EACR25-2546 Iris Garrido-Cano Poster Presenter Spain	Signaling Pathways affected by RAGE inhibition in vemurafenib treated melanoma cells P-331 EACR25-2550 Estelle Leclerc Poster Presenter United States	Berberine, a P-glycoprotein inhibitor, shows synergistic anti-cancer effect when combined with Dactolisib in Colorectal Carcinoma HCT116 cell lines P-332 EACR25-2572 Zeynep Busra Bolat Poster Presenter Turkey	ELUCIDATING TOPOTECAN-RESISTANCE MECHANISM IN HUMAN BREAST MCF-7 CANCER CELLS AND PACLITAXEL CROSS-RESISTANCE BY DNA DAMAGE SIGNALING PATHWAY GENE EXPRESSION. P-332A EACR25-24950 Erika Guerrero Poster Presenter Panama