POSTER SESSION - Wednesday

Poster Session Wednesday

Time	Session

10:45 20:00	BIOINFORMATICS AND COMPUTATIONAL BIOLOGY Deciphering Tumor-Immune Crosstalk Through Multiplexed Imaging-Powered Deep Visual Proteomics (mipDVP) P-001 EACR25-0123 Xiang Zheng Poster Presenter Denmark A clinically interpretable machine learning model using 19 proteins to predict recurrence/metastasis in OSCC patients P-002 EACR25-0205 Kaiyuan Sun Poster Presenter Hong Kong, China Identification of Olverembatinib as a Potential Inhibitor for ROR1+ Triple-negative Breast Cancer P-003 EACR25-0319 Onur Bender Poster Presenter Turkey Integrated Genomic and Structural Analysis Reveals Novel Insights into Polymerase Proofreading Deficiency Drivers P-004 EACR25-0321 Dana Dayan Poster Presenter Israel nf-hlamajority: a Nextflow pipeline for consensus MHC class I genotyping and its application to neoantigen identification in breast and lung cancer stromal cells P-005 EACR25-0449 Kevin Patrick Ryan Poster Presenter Ireland Integrative analysis of the TBXT-driven transcriptome and proteome in chordoma P-006 EACR25-0451 Cihan Erkut Poster Presenter Germany Classification of Small Blue Round Cell Tumors via mass spectrometry imaging of peptide and glycan content. P-008 EACR25-0475 Alice Ly Poster Presenter Belgium Comprehensive Pan-Cancer Multi-Omics Investigation of GCH1: Unraveling the Critical Role in Epithelial-Mesenchymal Transition P-903 EACR25-0619 Chihhsun Wu Poster Presenter Taiwan Describing Molecular Alterations in Breast Cancer Through a Multi-Omics Lens P-009 EACR25-0721 Anna Halama Poster Presenter Qatar Radiomics-based survival prediction in glioblastoma using the RaSPr score P-010 EACR25-0725 Kavita Kundal Poster Presenter India Multimodal inference of morphogenomic phenotypes using morphology and expression data optimal clustering (MEDOC) P-011 EACR25-0729 Ignasius Joanito Irwan Poster Presenter Singapore AI-Powered Nuclei Segmentation in Cervical Cytology: Advances with Deep Learning Models P-012 EACR25-0737 Rafael Parra-Medina Poster Presenter Colombia Comprehensive machine learning analysis of high-dimensional radiomics datasets by PYRAMID P-013 EACR25-0789 Simone Romagnoli Poster Presenter Italy Machine Learning Algorithms for Prediction of Bone Metastasis Risk in Patients with Lung Cancer P-014 EACR25-0985 Siu King Rachel Luk Poster Presenter Hong Kong, China Single-nuclei transcriptome profiling reveals vascular endothelial cell heterogeneity induced by VEGFA/BRAF targeting in murine melanoma model P-015 EACR25-1047 Rosaria Rita Chiarelli Poster Presenter Italy Characterization of a new breast cancer classification and identification of key regulators P-015A EACR25-1077 Nathan Laneret Poster Presenter France Investigating molecular evolution of tumor heterogeneity at recurrence unveils patient-specific trajectories P-016 EACR25-1099 Bakhtiyor Nosirov Poster Presenter Luxembourg Unified Whole Genome Sequencing for Hematological Malignancies P-017 EACR25-1175 Severine Catreux Poster Presenter United States DTFD-MIL-CN: A Cost-Effective and Accurate Deep Learning Model for Hormone Receptor–Positive, HER2-Negative Breast Cancer Distant Recurrence Risk P-018 EACR25-1225 LIULIU QUAN Poster Presenter China Deep transfer learning for predicting BRAF V600E mutation status in colorectal cancer using image-derived features associated with microsatellite instability P-019 EACR25-1229 Salim Salim Arslan Arslan Poster Presenter United Kingdom Spatial Transcriptomics Reveals Immune-Tumor Interactions Associated with Pembrolizumab Response in NSCLC P-020 EACR25-1255 Lipika Kalson Poster Presenter Austria Machine Learning Meets Man’s Best Friend: Uncovering Prognostic Factors in Canine Mammary Tumors P-021 EACR25-1257 Hedda Fjell Scheel Poster Presenter Norway Deciphering the Molecular Impact of Asbestos: Gene Expression Profiles in Malignant Pleural Mesothelioma P-022 EACR25-1353 Elisa Frullanti Poster Presenter Italy Pan-cancer analysis of signaling pathways regulatory connection with pyrimidine metabolism and its chemoresistance role P-023 EACR25-1395 Vignesh Ramesh Poster Presenter Denmark Enabling Clinical and Early-Phase Drug Development Applications through Single-Sample Tumor Archetype Assignment P-024 EACR25-1409 Mechthild L Poster Presenter Switzerland Artificial Intelligence-Based Polyp Size Measurement: Multinational Validation Across Endoscopic Datasets P-025 EACR25-1565 Sihyun Kim Poster Presenter Korea (Republic of) Accelerating real world data collection using Large Language Models in rare neoplasms. A bone sarcoma example. P-026 EACR25-1735 Szymon Rynkun Poster Presenter Poland Pan-Cancer Analysis Identifies Dorsomorphin Dihydrochloride as an Anticancer Drug Targeting the Notch Signaling Pathway P-027 EACR25-1741 Elif KUBAT OKTEM Poster Presenter Turkey Proteomic Analysis of the Pd(II) Complex-Induced Changes in HeLa Cervical Cancer Line P-028 EACR25-1799 Vanja Ralic Poster Presenter Serbia MOKCa-3D Database: Functional and structural analysis of gain-of-function and loss-of-function missense mutations in cancer. P-029 EACR25-1837 Frances Pearl Poster Presenter United Kingdom The S-RACE Platform: Empowering Healthcare Real-World Data with Artificial Intelligence (AI) Using a Cloud-Based Approach P-030 EACR25-1839 ALBERTO TRAVERSO Poster Presenter Italy integrative Molecular Tumor Board (iMTB): A Decision-Support Tool for Precision Cancer Medicine in iCAN P-031 EACR25-2023 Romika Kumari Poster Presenter Finland Evaluating computational and enzymatic strategies for artifact removal in FFPE-derived NGS data P-032 EACR25-2117 Wiktoria P_onka Poster Presenter Poland Optimization of U-Net-based semantic segmentation of fluorescence microscopy images P-909 EACR25-2175 Jakub Konrad Sarno Poster Presenter Poland Comprehensive Analysis of Fusion Transcripts in HCC: Implications for Gene Expression and Tumor Progression P-033 EACR25-2249 Yasemin Poster Presenter Turkey Unraveling Osteosarcoma Heterogeneity: molecular subtyping of early-stage osteosarcoma P-034 EACR25-2265 Pejic Jelena Poster Presenter Serbia Leveraging SHAP Values from Machine Learning and Mutational Signatures in Supervised Clustering to Enhance Disease-Specific Survival Prognosis in Endometrial Carcinoma P-035 EACR25-2347 Alberto Ivan Salido-Guadarrama Poster Presenter Mexico Tumor Growth Dynamics and Telomere Maintenance in Sarcoma: Insights from 3D Spheroid Models P-036 EACR25-2357 Karla Ostoji_ Poster Presenter Croatia The effect of common germline variants on tumor mutation burden and mutational signatures activity P-037 EACR25-2465 Alon Ravid Poster Presenter Israel Site-specific validation of the GRANT model for renal cell carcinoma (RCC) cancer-specific survival (CSS) after surgery P-038 EACR25-2501 ALBERTO TRAVERSO Poster Presenter Italy Radiomics-based classification of tumour subtypes in breast cancer using MRI imaging P-039 EACR25-2527 Damian Borys Poster Presenter Poland IRE1 signalinig in Triple Negative Breast Cancer P-040 EACR25-2597 Bianka Alexandra Pasat Poster Presenter Ireland Poster and Exhibition Hall
10:45 20:00	BIOMARKERS IN TISSUE AND BLOOD The Monocyte/Hemoglobin Ratio as a New Prognostic Biomarker in Patients with Advanced Pancreatic Adenocarcinoma P-041 EACR25-0111 Roc Poster Presenter Spain miRNAs in Serum and Extracellular Vesicles as Potential Biomarkers of Metastatic Disease in Clear Cell Renal Cell Carcinoma P-042 EACR25-0157 Kerstin Junker Poster Presenter Germany Immunohistochemistry expression of HER2, Ki-67, and Sialyl-Tn as biomarkers of poor prognosis from patients with gastric adenocarcinoma in Southeastern Mexico. P-042A EACR25-0245 Oscar Daniel Pacheco-Can Poster Presenter Mexico Genome-scale cell-free DNA methylation analysis for early detection and monitoring of lung cancer P-043 EACR25-0249 Euan Rodger Poster Presenter New Zealand Assessing the potential of specific Tubulin post-translational modifications as predictive biomarkers for taxane response in breast cancer. P-044 EACR25-0393 Sonia Pinela Silva Poster Presenter Portugal Developing a Targeted Plasma DNA Methylation Panel for Early Prostate Cancer Detection P-045 EACR25-0473 Jim Smith Poster Presenter New Zealand Predictive Signature of Response to Neoadjuvant Chemotherapy Based on Tumor-Educated Platelet mRNA Profiles in Muscle-Invasive Bladder Cancer P-046 EACR25-0499 Vicen Poster Presenter Spain Do small extracellular vesicles within serum of different thyroid pathologies express the same miRNA as those isolated from tissue-on-chip? P-047 EACR25-0529 Hannah Beattie Poster Presenter United Kingdom STRN4/Zinedin is a favourable prognostic indicator for patents with colon cancer P-048 EACR25-0547 Oscar Wickstead Poster Presenter United Kingdom CHI3L1 and CHI3L2 gene and protein expression in colorectal cancer P-906 EACR25-0567 Tsvetomira Georgieva Ivanova Poster Presenter Bulgaria The Impact of Circulating Malignant Tumour Cells on Tumour Recurrence in Oral Squamous Cell Carcinoma P-049 EACR25-0611 Abdulrahman Sakeen Alkandari Poster Presenter Kuwait Prognostic Potential of ctDNA Methylation in Prostate Cancer: Predicting Biochemical Recurrence and Overall Survival in Localized and Metastatic Disease P-050 EACR25-0689 Jae-Seung Chung Poster Presenter Korea (Republic of) Identification of Histopathological and Molecular alterations associated with High-risk Oral leukoplakia: A prospective study P-051 EACR25-0699 Rinal Pala Chavda Poster Presenter India Tumor educated platelets in diagnostics and monitoring of childhood brain tumors P-052 EACR25-0761 Amanda Anna Sylvia Holmstr Poster Presenter Finland Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) in ascitic fluid as a potential biomarker for Ovarian Cancer development and recurrence P-053 EACR25-0765 Francesca Gorini Poster Presenter Italy Proteomic profiling of bladder cancer patients-derived extracellular vesicles P-054 EACR25-0787 Catarina Martins Louren Poster Presenter Portugal Surface plasmon resonance for the detection of EGFRvIII in circulating extracellular vesicles from glioblastoma P-055 EACR25-0847 Amy Gateau Poster Presenter France Advancing Multi-Cancer Early Detection: High-Performance cell-free RNA Profiling with the Flomics Liquid Biopsy Platform P-056 EACR25-0849 Joao Curado Poster Presenter Spain Bridging Redox Biology and Immune Infiltrates for a Better Understanding of HER2+ Breast Cancer Outcomes P-057 EACR25-0887 Ana Sofia Fernandes Poster Presenter Portugal Age and Microenvironment Matter: When Survivin Becomes a Predictor of Poor Outcomes in Neuroblastoma P-058 EACR25-0899 Selene Elifio Esposito Poster Presenter Brazil Biomarkers for neo-adjuvant treatment in locally advanced rectal cancer: preliminary results from a comprehensive characterization of the biological features of good and poor response P-059 EACR25-1009 Huerta Ana Elsa Poster Presenter Spain Sex-Based Differences in Colorectal Cancer Patients: a Multi-Omics Perspective on Primary and Surrogate Tissues P-060 EACR25-1069 Benedetta Genta Poster Presenter Italy AKT3 as a candidate biomarker of platinum response in epithelial ovarian cancers P-061 EACR25-1091 SERENA BONIN Poster Presenter Italy Development of tumor-specific EV-miRNA signatures to improve lung cancer early detection (EV-miR-Test) P-062 EACR25-1131 Anna Alessia Saponaro Poster Presenter Italy Unraveling the Impact of Genetic Ancestry on Breast Cancer Neoadjuvant Chemotherapy Response: A Comprehensive Analysis P-063 EACR25-1189 Michelle Guevara-Nieto Poster Presenter Colombia Exploring cfDNA copy number profiles to characterize disease stages in pancreatic adenocarcinoma P-064 EACR25-1235 Luis Filipe Abreu de Carvalho Poster Presenter Belgium Investigation of miRNAs expression in Bulgarian patients with early-stage and advanced laryngeal cancer as a prognostic biomarker P-065 EACR25-1357 Gergana Stancheva Poster Presenter Bulgaria Novel Blood-Based mRNA Biomarkers: A Promising Approach for Non-Invasive Colorectal Cancer Screening P-066 EACR25-1397 Lu Poster Presenter Portugal What Drives the Expansion of Mutant Clones in Non-Malignant Gastrointestinal Tissues, and How Is This Related to Cancer Initiation? P-067 EACR25-1417 Firda Maruf Poster Presenter United Kingdom Investigating the sheddase (s) responsible for HAI-1 ectodomain release in bladder cancer cell lines P-068 EACR25-1423 Azad Kareem Saeed Poster Presenter United Kingdom Osteosarcoma biomarker discovery in plasma extracellular vesicles using a targeted proteomics approach P-069 EACR25-1443 Snehadri Sinha Poster Presenter Finland Exosomal miRNAs in Breast Cancer cancerogenesis: the EsomiR Study Update P-070 EACR25-1481 Barbara Cardinali Poster Presenter Italy Prognostic value of tumour-infiltrating immune cells in patients with nasopharyngeal carcinoma P-071 EACR25-1507 Jingyi Ma Poster Presenter Singapore The potential diagnostic value of a circulating serum-derived miRNA-based model in patients with colorectal cancer. P-072 EACR25-1529 Agnieszka Ostrowska Poster Presenter Poland Feasibility of tracking multiple primary cancers (MPCs) using tumor-informed circulating tumor DNA (ctDNA) assays P-073 EACR25-1533 Sumedha Sudhaman Poster Presenter Canada Computational screening for promising protein biomarkers and predictive performance evaluation for lung cancer P-074 EACR25-1591 Zonglun Li Poster Presenter United Kingdom Identification of novel diagnostic biomarkers as therapeutic targets in prostate cancer P-075 EACR25-1609 Narumol Bhummaphan Poster Presenter Thailand Multi-omics Approaches to Uncover Liquid-Based Cancer-Predicting Biomarkers in Lynch Syndrome P-076 EACR25-1611 Minta Eeva Maria K Poster Presenter Finland Virome-based Biomarkers for Non-Invasive Colorectal Cancer Screening P-077 EACR25-1769 Loretta De Chiara Poster Presenter Spain Genomic diversity and BCL9L mutational status in CTC pools predict overall survival in metastatic colorectal cancer P-078 EACR25-1801 Joao M Alves Poster Presenter Spain Xenograft derived from circulating tumor cells as a model for preclinical research P-079 EACR25-1841 Zuzana Kahounov Poster Presenter Czech Republic Non-invasive bladder cancer detection: identification of a urinary volatile biomarker panel using GC-MS metabolomics and machine learning P-080 EACR25-1857 Poster Presenter Portugal Photodynamic laser therapy decreases inflammation in oral lichen planus patients P-081 EACR25-1903 Milena Nenkova Draganova Poster Presenter Bulgaria Expression of GSK3β and S6K1 mRNA in triple negative breast cancer P-082 EACR25-1947 Tijana Tomi_ Poster Presenter Serbia Mutational enrichment of CTCs and CTC clusters from breast cancer xenografts P-083 EACR25-1955 Nuria Est Poster Presenter Spain Activated CD4+ T cells as prognostic and predictive biomarkers in cutaneous melanoma P-084 EACR25-1961 Ana Tom Poster Presenter Portugal Characterization and evaluation of CD24 and NPY as biomarkers for metastatic castration-resistant prostate cancer (mCRPC) P-085 EACR25-1963 Peter Ryan McHenry Poster Presenter Lebanon Tissue Factor (TF) and Factor VII/TF Ratio (fVIIa:TF ) as Potential Indicators of Malignancy in Pancreatic Cystic Lesions P-086 EACR25-1993 Farzana Haque Poster Presenter United Kingdom Morphometric analysis of neoplastic cell clusters in high-grade serous ovarian cancer ascites may prove to be a novel prognostic factor: a retrospective study P-087 EACR25-2029 Beno Poster Presenter France miRNAs as biomarkers of PARP inhibitors resistance in ovarian Patient-Derived Tumor Organoids P-088 EACR25-2073 Jade RICHARD Poster Presenter France Development of novel biomarker-based methods for early detection of cancer aggressiveness and cancer treatment stratification in Head and neck squamous cell carcinoma. P-089 EACR25-2095 Priyadharshini Parimelazhagan Santhi Poster Presenter Finland Unveiling the Role of EVs-derived miR-15b-5p, -1293, -376a-3p in Clear Cell Renal Cell Carcinoma Progression P-090 EACR25-2143 V Poster Presenter Portugal Advanced detection of targetable gene-drivers: tracking ctDNA changes using digital PCR in liquid biopsies of advanced non-small cell lung cancer (NSCLC) P-091 EACR25-2161 Katherine Brown Poster Presenter United Kingdom Performance of a novel NGS-based technology for mutation profiling in liquid biopsies derived from metastatic colorectal cancer patients P-092 EACR25-2209 Pirjo Nummela Poster Presenter Finland Machine learning-driven Integration of bulk transcriptomics and spatial analysis for prognostic stratification in unresectable high-grade serous tubo-ovarian cancer P-093 EACR25-2231 Raffaella Ergasti Poster Presenter Italy Detection of Aggressive Prostate Cancer in Urine by Fragment-Level DNA Methylation P-094 EACR25-2237 Tibor Bedekovics Poster Presenter United States A Novel Multimodal Liquid Biopsy workflow for the characterization of Circulating Tumor Cells in Metastatic Breast Cancer P-095 EACR25-2273 Roberta Carbone Poster Presenter Italy Identification of outcome-associated tumor perivascular features in renal cell carcinoma P-097 EACR25-2281 Alfonso Mart Poster Presenter Sweden UHRF1 role in the repression of Embryonic Morphogenesis genes predicts better prognosis and improves clinical and molecular classification in gastric cancer P-098 EACR25-2369 Ian Marc Bonapace Poster Presenter Italy Pre-cancer MicroRNA Profile of Normal Tissues Adjacent to Tumor (NAT) in HER2-positive Subtype of Breast Cancer. P-099 EACR25-2389 Vinitha Richard Poster Presenter Ireland Genome-wide DNA methylation profiling reveals a novel DNA methylation signature for early detection of oral cancer using saliva based liquid biopsy P-100 EACR25-2431 Poster Presenter Spain Influence of opioid analgesia, opioid and cannabinoid receptors expression in tumor tissue on survival of patients with pancreatic cancer P-101 EACR25-2437 Monika Vidlarova Poster Presenter Czech Republic Exploiting the heterogeneity of Tumour-derived Extracellular Vesicles in breast cancer to establish proteomic signatures as prognostic biomarkers in liquid biopsies P-102 EACR25-2453 Amalia Vogiatzoglou Poster Presenter Greece Deciphering the Potential of Liquid Biopsies Based on Circulating Cell-Free DNA as a Biomarker for Head and Neck Cancer Management P-103 EACR25-2467 Ana Maria Poster Presenter Spain Unraveling Extracellular Vesicle MicroRNA Signatures as Novel Biomarkers and Therapeutic Targets in Sarcopenic Hepatocellular Carcinoma P-104 EACR25-2479 Giulia Savino Poster Presenter Italy Comparative Analysis of Technologies for Circulating Tumor Cell Capture, Purity, and Survival: A Comprehensive Evaluation P-105 EACR25-2523 Cyro von Zuben Poster Presenter Brazil Proteomic quantification of receptor tyrosine kinases in small intestine, colon, appendix and peritoneum tumours P-106 EACR25-2555 Areti-Maria Vasilogianni Poster Presenter United Kingdom Unraveling Novel Metastasis Biomarkers: Liquid Biopsy to Guide Treatment Decision in Colorectal Cancer P-107 EACR25-2577 Luc Poster Presenter Portugal Poster and Exhibition Hall
10:45 20:00	CANCER CELL BIOLOGY The role of SLC7A9 in inducing ferroptosis resistance in colorectal cancer P-108 EACR25-0021 Wenqing Jia Poster Presenter China Innovation and Optimization of Surgical Treatment Strategies for Gliomas P-109 EACR25-0023 Rui Zhao Poster Presenter China Comprehensive bioinformatics analysis DNA damage repair gene with prognosis and immune response in Lung adenocarcinoma P-110 EACR25-0063 gang De Zou Poster Presenter China How to kill your fibroblasts and save the cancer stem cells in your culture P-111 EACR25-0117 Alexander Trampe Poster Presenter Germany The role of integrin β1 phosphorylation dynamics during breast cancer invasion P-111A EACR25-0121 James RW Conway Poster Presenter Finland Novel applications of senolytics to prevent treatment resistance in cervical cancer P-112 EACR25-0159 Madre Meyer Poster Presenter South Africa Carboplatin-induced transcriptional landscape and growth morphology of ovarian cancer cell models growing in 3D stem-cells supporting environment P-113 EACR25-0161 Anamaria Brozovic Poster Presenter Croatia Progesterone receptor plays pivotal roles in regulating mitochondria function and mitochondria mediated caspase-independent apoptosis in breast cancer cells P-114 EACR25-0195 Valerie CL Lin Poster Presenter Singapore Short-term fasting and zinc ionophores cooperate to promote ferroptosis in colorectal cancer P-115 EACR25-0237 Amr Khalifa Poster Presenter Italy Can transient inactivation replace loss of the wildtype tumor suppressor as the second hit for colorectal cancer initiation? P-116 EACR25-0335 Peh Yean Cheah Poster Presenter Singapore PTX3 Promotes Tumor Cell Migration Through the miR-1255b/CYP2J2 Axis in Oral Cancer P-117 EACR25-0337 Yang Shun-Fa Poster Presenter Taiwan Sequential Targeting of IAP and BCL-2 Family Proteins May Enhance Apoptotic Sensitivity in Non-Small Cell Lung Cancer P-118 EACR25-0353 Baris Budak Poster Presenter Switzerland Treatment with 3-bromopyruvate boosts the effect of chemotherapy in acute myeloid leukemia P-119 EACR25-0373 Joana Pereira Vieira Poster Presenter Portugal A novel role of Kinesin Family Member 20A (KIF20A) in Hepatocellular carcinoma cell metabolism and ferroptosis P-120 EACR25-0433 Keshi Zhou Poster Presenter China Cingulin expression and clinical/prognostic value in breast cancer P-121 EACR25-0455 Yufei Lou Poster Presenter United Kingdom SPINT2 Expression in Cancer: Focus on Its Role and Therapeutic Impact in BRAF-Mutated Melanoma P-122 EACR25-0463 Sonia Celeiro Poster Presenter Portugal The Role of ADAMTS1 in Oral Squamous Cell Carcinoma: Impact on Invasion, Lymph Node Metastasis, and Prognosis via the ADAMTS1-L1CAM-EGFR Signaling Axis P-123 EACR25-0467 Wei-Jiunn Lee Poster Presenter Taiwan Exploiting Cellular Senescence to Enhance Precision Oncolytic Immunotherapy P-124 EACR25-0491 Yvonne Giannoula Poster Presenter Finland Fuelling the fight: The Impact of a Ketogenic Diet on Chemotherapy-induced DNA damage in Acute Leukemia P-125 EACR25-0515 Gayathiri Rajakumar Poster Presenter Australia High levels of DNA replication initiation factors lead to ATRi sensitivity via excessive origin firing P-126 EACR25-0533 Audrey Lumeau Poster Presenter United Kingdom LAMP1, LAMP2 and LAMP2A IN COLORECTAL CANCER: POTENTIAL PROGNOSTIC BIOMARKERS? P-127 EACR25-0543 _____ Stepan ______ Poster Presenter Bulgaria The DC6-KSP signaling Pathway is essentially required for Metabolic Adaptation and Leukemic Progression P-128 EACR25-0563 Kwon Hyog Young Poster Presenter Korea (Republic of) Understanding the interplay of EPHA2 and CD44 in colorectal cancer stemness, EMT and therapy resistance. P-129 EACR25-0577 Aditya Nigam Poster Presenter Italy Role of mast cells in promoting breast cancer stem-like properties via heparanase and MUC1/estrogen receptor axis P-130 EACR25-0581 Daniele Lecis Poster Presenter Italy TRIB2 overexpression impairs autophagy flux and compromises efficient clearance of cellular cargo P-131 EACR25-0589 Bibiana I. Ferreira Poster Presenter Portugal Combined oncogene and pyruvate dehydrogenase kinase inhibition enhances tumor response in resistant NSCLC cells P-132 EACR25-0655 Camilla Carmela Tufano Poster Presenter Italy Polycomb Complex Protein PHC3 Coordinates with HOTAIR Pathway to Promote Colorectal Cancer Progression P-133 EACR25-0719 Yu Chang Chen Poster Presenter Taiwan Identification and Functional Characterization of Theranostic Biomarkers in Pancreatic Ductal Adenocarcinoma P-134 EACR25-0731 Yuh-Pyng Sher Poster Presenter Taiwan The protooncogene SETDB1 affects microtubule dynamics through HDAC6 P-135 EACR25-0767 Gabi Gerlitz Poster Presenter Israel Impact of the E2F1-BASP1 complex on regulating MYC expression P-136 EACR25-0845 Lea Emmy Timpen Poster Presenter Austria PARP12 as a Novel Therapeutic Target in Breast Cancer: Integrating ADP-Ribosylation, DNA Damage Response, and Hormone Therapy Resistance P-137 EACR25-0855 Giovanna Grimaldi Poster Presenter Italy Investigating the Cell of Origin in Merkel Cell Carcinoma Using a Human Pluripotent Stem Cell-derived Model P-138 EACR25-0869 Neelima Pradeep Vasantham Poster Presenter Switzerland Aldehyde metabolism as a target for metastatic melanoma P-139 EACR25-0873 Alba Roca Portoles Poster Presenter Spain The TMBIM4 Golgi Apparatus Ion Channel Supports Cancer Cell Survival by Altering Cysteine Availability P-140 EACR25-0875 Nuno Saraiva Poster Presenter Portugal Role of the collagen hydroxylase LEPRE-1 in breast cancer P-141 EACR25-0877 Chlo Poster Presenter Belgium SMALL EXTRACELLULAR VESICLE-DRIVEN FERROPTOSIS: A NOVEL STRATEGY TO TARGET THERAPY-RESISTANT OVARIAN CANCER P-142 EACR25-0885 Juan Antonio Fafian Labora Poster Presenter Spain Triple-negative breast cancer cell survival strategies under acute and chronic hypoxia P-143 EACR25-0947 Olesja Rogoza Poster Presenter Latvia Therapy-resistance of TP53 mutated cancers overcomes by targeting BIRC5 dependency P-143A EACR25-0949 Ahmed Mohamed Mamdouh Mohamed Poster Presenter Singapore Metabolic rewiring in the therapy-induced secretome facilitate glioblastoma resistance to radiotherapy P-144 EACR25-0965 Jeraldine Poh Poster Presenter Singapore Inhibition of arginase-2 differentially affects cell proliferation in breast cancer cell lines representing different clinical subtypes in vitro. P-145 EACR25-0981 Antonia R Poster Presenter Germany Macrophages stimulate glioblastoma motility and invasion through paracrine signaling leading to the regulation of Rho GTPases P-146 EACR25-0999 Mirvat Nabil El Sibai Poster Presenter Lebanon PD-L1 expression is essential for EGFR signaling- and fatty acid-enhanced metastasis in head and neck cancer P-147 EACR25-1007 Jing-Ting Chiou Poster Presenter Taiwan GATA4 drives metaplasia and cancer initiation from foregut keratinocytes in vivo P-148 EACR25-1031 Aliz Poster Presenter Belgium Generation of a monoclonal antibody anti CD36 for anti cancerous immunotherapies mediated by natural killer cells P-149 EACR25-1071 Sara Zemiti Poster Presenter France Deciphering the role of MET/NMDAR complex in colorectal cancer pathogenesis P-150 EACR25-1083 Consolata Beatrice Folco Poster Presenter Italy Characterizing the partial epithelial-mesenchymal transition and invasion in a colorectal cancer in vitro model P-151 EACR25-1111 Zolt Poster Presenter Hungary p140Cap-mediated reduction of the stem cell pool enhances breast cancer chemosensitivity P-143B EACR25-1145 Andrea Scavuzzo Poster Presenter Italy DNA methylation landscape defines metastatic routes in high grade serous carcinoma P-152 EACR25-1157 Giovanni Marchi Poster Presenter Finland Autophagic Cell Death in GBM Cells Following Arginine Deprivation is Mediated by Ferroptosis P-153 EACR25-1167 Ralph Joseph Abi-Habib Poster Presenter Lebanon The Potential Role of PAK4 in PDGF-BB-Mediated EMT and Metastatic Processes in Triple Negative Breast Cancer P-154 EACR25-1231 Feyza Kostak Poster Presenter Turkey PSMG2 role in tumorigenesis and stemness mediated by protein accumulation, reticulum stress and autophagy. P-155 EACR25-1241 Asunci Poster Presenter Spain PP2A inhibitor proteins CIP2A and PME-1 as medulloblastoma oncoproteins and therapy targets. P-156 EACR25-1243 Oxana Denisova Poster Presenter Finland Age-associated mitochondrial dysfunction drives CAR-T cell failure P-157 EACR25-1309 Helen Carrasco Hope Poster Presenter Switzerland Characteristics and Effects of Stemness Genes in Primary and Recurrent Ovarian Cancers and Ovarian Cancer Stem Cells P-158 EACR25-1351 Ece Gumusoglu-Acar Poster Presenter Turkey Oncogenic variants in GNAQ and GNA11 cause dysregulation of calcium signalling in uveal melanoma P-159 EACR25-1365 Davide Zecchin Poster Presenter United Kingdom Patient-derived organoid models to investigate the role of tryptophan in colorectal cancer progression P-160 EACR25-1369 Damerell Victoria Poster Presenter Germany Modelling multiple FGFR1 mutations uncovers modulatory effects and novel tumorigenic mechanisms in glioneuronal tumors. P-161 EACR25-1377 Jacopo Boni Poster Presenter Spain Mevalonate Pathway Suppresses Ferroptosis and Promotes Liver Cancer via CoQ10 Production and Selenocysteine-tRNA Modification P-162 EACR25-1387 Yiling Chen Poster Presenter Hong Kong, China ROBO receptors act as tumor suppressors in cholangiocarcinoma P-163 EACR25-1389 Aslihan Inal Poster Presenter Germany Effects of Asparaginase-induced amino acids deprivation on Triple Negative Breast Cancer cell lines P-164 EACR25-1391 Andrea Previtali Poster Presenter Italy Proteo-transcriptomic characterization of the CD14-CD34+ stem and progenitor cells in chronic myeloid leukemia P-165 EACR25-1411 Hana Komic Poster Presenter Sweden Spastin Functions in Glioblastoma Multiforme Migration Through Focal Adhesion Kinase Signaling Pathway P-166 EACR25-1427 ARZU KARABAY Poster Presenter Turkey DDB2-PCNA interaction is involved in maintaining genome stability in human UV-irradiated cells P-167 EACR25-1431 Anna Tricarico Poster Presenter Italy The BASP1 signaling protein interferes with the WNT signaling pathway P-168 EACR25-1441 Leonie Weber Poster Presenter Austria The Golgi Apparatus Protein TMBIM4 Promotes Glioma Cell Invasion and Metabolic Adaptation P-169 EACR25-1479 Marta Martins Poster Presenter Portugal RECREATING A METASTATIC LIVER MODEL TO UNVEIL THE ROLE OF CANCER STEM CELLS IN PANCREATIC DUCTAL ADENOCARCINOMA PROGRESSION AND THERAPEUTIC TARGETING P-170 EACR25-1497 Giselle Xavier Poster Presenter Spain Loss of UFMylation supports prostate cancer metastasis and rewires cell metabolism towards hexosamine biosynthesis P-171 EACR25-1503 Laura Bozal Basterra Poster Presenter Spain NGFR-Driven Lipid Metabolic Reprogramming in CR-CSCs: Implications for Chemoresistance in Colon Cancer P-172 EACR25-1523 Noemi Di Miceli Poster Presenter Italy C/EBPα coordinates key metabolic pathways driving the resistance to targeted therapies in FLT3-mutated acute myeloid leukemia P-173 EACR25-1525 Laura Lauture Poster Presenter France Impact of prevalent KRAS mutations in PDAC resistance to FIRINOX. P-174 EACR25-1541 Alba Hidalgo Ram Poster Presenter Spain Unbiased Phosphoproteomic and Metabolic Profiling in WT and KRAS Mutant Colorectal Cancer Cells Reveals Molecular Interplay Between Protein Regulation and Metabolic Rewiring P-175 EACR25-1545 Ethan Stancliffe Poster Presenter Evaluation of novel, high-affinity SSTR2/SSTR5 somatostatin analogs in pancreatic and pituitary neuroendocrine tumor models. P-176 EACR25-1551 Margarita Bistika Poster Presenter Italy CK2α and CHIP crosstalk: uncovering its role in tumorigenic processes P-177 EACR25-1555 Subhajit Karmakar Poster Presenter India Investigating the role of PTX3 in the biology of glioblastoma P-178 EACR25-1557 Camilla Tavani Poster Presenter Italy Attaching to and Crossing Endothelial Barriers P-179 EACR25-1571 Guillaume Jacquemet Poster Presenter Nucleotide imbalance sensed by p53 leads to an upregulation of pyrimidine salvage transporter hCNT1 P-180 EACR25-1599 Marta Mata Jurado Poster Presenter Spain Evaluation of Anti-Cancer Effects of Omeprazole in Prostate Cancer Cells P-181 EACR25-1615 Poster Presenter Turkey Therapy-induced senescence shapes tumor biology and treatment outcome in hepatoblastoma P-182 EACR25-1635 Lara Fankh Poster Presenter Germany Highlighting the Small GTPase RhoA as a New Therapeutic Target in ALK+ ALCL P-183 EACR25-1645 Vera Mugoni Poster Presenter Italy Deciphering the Role of CMA in Platinum Resistance: The Impact of LAMP2A in OCCC P-184 EACR25-1661 Gizem Y Poster Presenter Turkey Modulation of SUMOylation machinery complex proteins induces cell death in human colorectal cancer cells P-185 EACR25-1675 Mohammed Salih Poster Presenter United Kingdom α-Mangostin as a potential adjuvant in HER2+ breast cancer treatment P-186 EACR25-1695 Daniela Amador Poster Presenter Mexico Vemurafenib impairs mitochondrial bioenergetics and modulates stress-related transcript levels in the RAB-1 cell line: a multidisciplinary perspective in translational medicine for histiocytic lesions P-187 EACR25-1739 Agnieszka Aleksandra Smieszek Poster Presenter Poland Aurora-A-mediated Maf1 phosphorylation plays a novel role by regulating mitochondrial function in hepatocellular carcinoma P-188 EACR25-1743 YU HENG KUAN Poster Presenter Taiwan INCREASED INTRACELLULAR HYDROGEN SULFIDE PRODUCTION REDUCES CHEMICALLY-INDUCED HEPATOCARCINOMA PROGRESSION AND EXTENDS LIFESPAN IN MICE. P-189 EACR25-1761 Inmaculada Pino P Poster Presenter Spain The role of CEMIP and CTCF in castration-resistant prostate cancer: A novel insight from 3D spheroid model P-190 EACR25-1767 Ms. Salida Ali Poster Presenter The mTORC2-AKT-GSK3-FBXW7 Axis Regulates ELP1 Stability and U34 tRNA Modifications in Lung Cancer P-191 EACR25-1771 debora EHLARDO Poster Presenter Belgium PRKCz benefits melanoma brain metastases P-192 EACR25-1783 Lisa Sch Poster Presenter Germany TGF-β Resistance as a Collateral Mechanism to Senescence Escape and Tumor Aggressiveness in Hepatocellular Carcinoma P-193 EACR25-1821 Minenur Kalyoncu Poster Presenter Turkey C6ORF15 is a driver of lymph node metastasis through upregulation of EMT in colorectal cancer P-194 EACR25-1845 Dedrick Kok Hong Chan Poster Presenter Singapore Tackling oxidative phosphorylation of glioblastoma-initiating cells by specifically impairing 1 transmembrane Chloride Intracellular Channel 1 P-195 EACR25-1847 Guido Rey Poster Presenter Italy Unraveling CIP2A’s impact on DNA damage response in basal- like triple-negative breast cancer P-196 EACR25-1853 Phuong Doan Poster Presenter Finland MyomiR-133b suppresses colorectal cancer cell proliferation and modulates expression of multiple gene targets P-197 EACR25-1865 Jana Babulicov Poster Presenter Slovakia Identifying the role of PLEKHS1 in cancer P-198 EACR25-1889 Emily Charlotte Gill Poster Presenter United Kingdom Miro1 depletion modulates intracellular ATP distribution and adhesion dynamics, suppressing cell migration and metastasis in B16 melanoma cells P-199 EACR25-1897 Gabriela Oliveira Poster Presenter Portugal Flow-Based Cell Deformation Reveals EMT-Driven Mechanical Phenotype Changes in Metastatic Prostate Cancer P-200 EACR25-1909 Gumulec Jaromir Poster Presenter Czech Republic The Role of Brown Adipose Tissue in Pancreatic Cancer Progression P-201 EACR25-1933 Nieves Casillas-Ruiz Poster Presenter Spain Cell-free DNA (cfDNA) regulates metabolic remodeling influencing cancer cell proliferation, quiescence, and chemoresistance P-202 EACR25-1967 Isabel Lemos Poster Presenter Portugal Transcriptional Dosage of Oncogenic KRAS Drives Lung Adenocarcinoma Cell States and Evolution P-203 EACR25-1991 Gaetano Gargiulo Poster Presenter Germany Mitochondrial damage triggers therapy-induced senescence P-204 EACR25-2009 Mark Cornelis de Gooijer Poster Presenter Netherlands Endothelial pyrimidine synthesis restricts tumor growth P-205 EACR25-2025 Katerina Rohlenova Poster Presenter Czech Republic Targeting Tumor Metabolism to Prevent the Development of Resistance to Cisplatin in Ovarian Cancer P-206 EACR25-2031 Elena Capellini Poster Presenter Italy Utilizing BioID to Identify Interaction Partners of Haspin Kinase P-207 EACR25-2041 Karel Sou_ek Poster Presenter Czech Republic Characterization of Cancer Stem Cells in Osteosarcoma Progression P-208 EACR25-2059 Karla Ostoji_ Poster Presenter Croatia The long non-coding RNA H19 promotes cell proliferation, migration, and invasion in breast cancer through the H19/miR-X/BST2 axis P-209 EACR25-2065 Kekely Klouyovo Poster Presenter France Investigating the role of miR-500 in metastasis-related processes in LLC1 cells P-210 EACR25-2077 Kamile Normantaite Poster Presenter Lithuania IDH1 mutation induces differential DNA repair and metabolic profiles in glioma P-211 EACR25-2079 Maria In Poster Presenter Portugal Hypoxia-Driven Fatty Acid Metabolism Regulates Angiogenesis in Gastrointestinal Cancers P-212 EACR25-2085 Alessio Biagioni Poster Presenter Italy The Oncofetal Protein ROR1 Drives Cancer Stemness and Metastasis in Hepatocellular Carcinoma through Actin Cytoskeleton Remodelling P-213 EACR25-2093 Yanshu Kong Poster Presenter Hong Kong, China Unraveling the PKM2 Nexus: Metabolic Reprogramming, Nuclear Regulator, and p38 MAPK-Signaling Driven Drug Resistance in Colorectal Cancer P-214 EACR25-2141 Zeinab Attar Poster Presenter Germany Assessing the impact of endolysosomal Two-pore channel 2 (TPC2) on malignant melanoma aggressiveness P-215 EACR25-2157 Martina Meucci Poster Presenter Italy The SuSe Model: A Dual-Marker Approach to Investigate the Impact of Senolytic Therapy in Cancer P-216 EACR25-2169 Marta Lalinde Guti Poster Presenter Spain Dual-targeted therapy: Novel interventions to inhibit metastasis and chemoresistance in cervical cancer P-217 EACR25-2217 Cayleigh Cayleigh de Sousa Poster Presenter South Africa Novel molecular insights of gastric cancer dissemination and prognosis P-218 EACR25-2219 Estefania Carrasco Garcia Poster Presenter Spain Epigenetic and Metabolic Consequences of JMJD5 Loss in Hepatocellular Carcinoma P-219 EACR25-2221 Abu Zaid Khan Poster Presenter United Kingdom Nuclear receptor NR5A2 negatively regulates HIF-1alpha signaling to inhibit tumor-specific metabolic adaptations in glioblastoma cells: potential novel therapeutic implications via NR5A2 targeting P-220 EACR25-2227 Dimitrios Gkikas Poster Presenter Greece In vitro tranformation of primary uveal melanocyte into uveal melanoma. P-221 EACR25-2233 Alice Darchen Poster Presenter France Exploiting senolytic drugs to strike brain tumors metabolic vulnerabilities P-222 EACR25-2251 Martina Canton Poster Presenter Italy Therapeutic overactivation of oncogenic signaling to improve outcomes in Ewing sarcoma P-223 EACR25-2267 Amber Amparo Poster Presenter Netherlands The Androgen Receptor Mediates Immune Evasion and Progression of Melanoma P-224 EACR25-2287 Carmela Sorrentino Poster Presenter Italy Inflammatory secretome from triple negative breast cancer cells drives EMT and enhances migration in non-cancerous breast cells P-225 EACR25-2289 Mercedes Nadal Serrano Poster Presenter Spain Synergistic cell cycle blockade with the combination of CDK4/6 PROTACs and a CDK2 inhibitor as a potential anticancer strategy P-226 EACR25-2297 Alicja Stanislawa Slota Poster Presenter Poland Induction of ferroptosis and senescence in epithelial ovarian cancer cell line: Implications of targeted therapeutic strategies P-227 EACR25-2301 Lama Berjawi Poster Presenter Spain Investigating the relationship between IGF signalling, androgens and amyloid precursor protein (APP) processing in prostate cancer P-228 EACR25-2333 Rachel Barker Poster Presenter United Kingdom Targeting endometrial cancer stem cells with an ALDH-mediated photodynamic therapy P-229 EACR25-2345 Mafalda Laranjo Poster Presenter Portugal MBNL1 as regulator of doxorubicin resistance in triple negative breast cancer P-230 EACR25-2351 Iris Garrido-Cano Poster Presenter Spain Translational control of BRAF and NRAS oncogene-driven MAPK signaling in malignant melanoma P-231 EACR25-2359 Uldrijan Stjepan Poster Presenter Czech Republic Metabolic Reprogramming and Phenotypic Adaptation in Colorectal Cancer Cells Exposed to a Hypertrophic Adipose Microenvironment P-232 EACR25-2361 Paula de Juan Maci Poster Presenter Spain Role of MRPL15 in mitochondrial dynamics, cell cycle, and EMT regulation in different breast cancer subtypes. Implications for tumor progression. P-233 EACR25-2387 Jorge Sastre-Serra Poster Presenter Spain ABCC1 is responsible for invasive phenotype development in colon cancer P-234 EACR25-2401 Wojciech Michal Ciszewski Poster Presenter Poland Role of the NEDD4 family of E3 ubiquitin ligases in regulating the size of connexin43-based gap junctions in cervical cancer cells P-235 EACR25-2421 Max Zachrisson Totland Poster Presenter Norway tRNA Optimality Shapes Colorectal Cancer Stem Cell Identity Through Regulation of mRNA Translation P-236 EACR25-2445 Lorena Martin Morales Poster Presenter Belgium AMPK as a regulator of glioblastoma invasion and cytoskeleton dynamics P-237 EACR25-2447 Sabela Caama Poster Presenter Spain The Transcription Factor SNAI2 as a Novel Mediator of EWS-WT1 (+KTS) Oncogenic Activity in Desmoplastic Small Round Cell Tumour P-238 EACR25-2459 Laura Lobo Selma Poster Presenter Spain Asparagine-driven transsulfuration compensates for malate-aspartate shuttle deficiency in tumor growth P-239 EACR25-2469 Jakub Rohlena Poster Presenter Czech Republic Divergent Effects of Tet2- and Dnmt3a-mutant Clonal Hematopoiesis on Breast Cancer Progression Upon Aging P-240 EACR25-2489 Nagihan Gizay G Poster Presenter Switzerland IL-2/STAT5 signalling drives metabolic reprogramming to support cervical cancer cell proliferation P-241 EACR25-2579 Isabel Soto Poster Presenter Mexico HiBiT-Tagged CRISPR Cell Line Engineering: Enabling Antibody-Free Protein Quantification and Targeted Degradation Analysis in Cancer Research P-241A EACR25-2585 Zofia Swiatczak Poster Presenter United States Cancer associated fibroblasts regulate breast cancer migration through Laminin-511 P-242 EACR25-2587 MALLAR BANERJEE Poster Presenter India PPP2R2B-derived circRNA in the suppression of ferroptosis in Pancreatic cancer cells P-243 EACR25-2589 Jessica Jazmin Pena Paladines Poster Presenter Hong Kong, China A20: a potential target to boost immune checkpoint blockade in EGFR driven lung tumors EACR25-2531 EACR25-2531 Herwig Peter Moll Poster Presenter Austria Poster and Exhibition Hall
10:45 20:00	CANCER GENOMICS Genomic and single-cell characterization of patient-derived tumor organoid models of head and neck squamous cell carcinoma P-244 EACR25-0001 park young min Poster Presenter Korea (Republic of) Genes that affect DNA repair and calcium metabolism predispose to Malignant Mesothelioma P-245 EACR25-0013 Flavia Novelli Poster Presenter United States Genome-wide CRISPR Screening in Embryonic Stem Cells Identifies Synthetic Lethality Interactions in MLH1 and TP53 Deficient Tumors P-247 EACR25-0241 Guy Haim Poster Presenter Israel The use of ultra-low-pass sequencing data to classify tumors' molecular deficiencies P-248 EACR25-0317 Stav Naky Poster Presenter Israel Whole-genome CRISPR-Cas9 screens identify SHOC2 as a genetic dependency in NRAS-mutant melanoma P-249 EACR25-0429 Andrea Gu Poster Presenter New Zealand Molecular Evolution of Driver Mutations in Cancer with Microsatellite Instability and Their Impact on Tumor Progression: Implications for Precision Medicine in Patients with UCEC P-250 EACR25-0437 Jim Jinn-Chyuan SHEU Poster Presenter Taiwan Spatial proteomic profiling of tumor microenvironment dynamics in ER-positive breast cancer P-251 EACR25-0489 Maria Aanesland Dahle Poster Presenter Norway Advancing Biobanking in Europe to foster Cancer Research P-252 EACR25-0519 Manuela Pausan Poster Presenter Austria Integrative Analysis Reveals RNF135 as a Prognostic and Immunological Biomarker in Glioblastoma P-253 EACR25-0617 Etame Arnold Poster Presenter United States Functional diversity of the TP53 mutational landscape revealed by saturating genome editing P-254 EACR25-0673 Julianne Funk Poster Presenter Germany Genetic Profiling of Homologous Recombination Repair Pathway Alterations in Ovarian Cancer patients’ cohort from Serbia P-255 EACR25-0803 Katarina Zivic Poster Presenter Serbia Single-Cell Multi-omics with InTraSeq Uncovers Novel Insights into Th17 Differentiation P-256 EACR25-0907 Maxime Jacquet Poster Presenter France Distinct Mutational Profiles in Primary Sclerosing Cholangitis-Associated Cholangiocarcinoma Compared to de novo Cholangiocarcinoma P-257 EACR25-0921 Shulan Tian Poster Presenter United States Massively scalable direct guide RNA capture for pooled CRISPR screening P-258 EACR25-0959 Sue Ann Molero Poster Presenter Germany Different mutational patterns in primary colorectal cancer and its paired synchronous or metachronous metastasis and their association with patient outcomes P-259 EACR25-0971 Filip Ambrozkiewicz Poster Presenter Czech Republic Saturation mutagenesis of the FGFR kinase domains reveals all activating point mutations and their drug response P-260 EACR25-0979 Luise Carmina Viardot Poster Presenter Germany Arm-level somatic copy number alterations in liver metastases of colorectal carcinoma associated with time to relapse after surgical resection P-261 EACR25-1011 Petr Hol_ Poster Presenter Czech Republic Genomic instability and mitochondrial dysfunction drive high grade serous ovarian cancer P-262 EACR25-1073 Colin Semple Poster Presenter United Kingdom “Hello from the other side” – Exploring the interplay between cancer cell metabolism and immune cells in Ductal Carcinoma In Situ (DCIS) P-263 EACR25-1081 Helga Bergholtz Poster Presenter Norway Investigating the molecular diversity of luminal breast cancer arising in young women P-264 EACR25-1135 Lorena Musco Poster Presenter Italy KRAS mutation derived PSMB8 activates MEK/ERK signaling to promote chemoresistance in pancreatic adenocarcinoma P-265 EACR25-1195 Xu Haiyan Poster Presenter China Analysis and machine-learning based prediction of cellular adaptation during ovarian cancer treatment. P-266 EACR25-1261 Rene Wong Poster Presenter Finland Single-Cell Analysis Reveals U1 snRNA Mutation–Driven Tumor Microenvironment Remodeling in Chronic Lymphocytic Leukemia via CD44 Signaling P-267 EACR25-1281 Sara L Poster Presenter Spain Investigating Topoisomerase IIβ Binding Protein 1 as a Potential Prognostic Biomarker and Therapeutic Target in Bladder Cancer P-268 EACR25-1317 Amani Yehya Poster Presenter Lebanon Origin of chromosomal instability during acinar to ductal metaplasia in pancreatic cancer P-269 EACR25-1323 Francisco Javier Mendoza Le Poster Presenter Spain Method Development of Single Cell Readable Stress Signal Recording System P-270 EACR25-1335 Joona J Poster Presenter Finland Isoform Switching in Different Grades of Non-Muscle Invasive Bladder Cancer (NMIBC): Changes in Gene Function without Changes in Gene Expression P-271 EACR25-1403 Esra Hilal Yuksek Tekben Poster Presenter United Kingdom Identifying immune cell phenotypes and their function by using high throughput spatial multiomics P-272 EACR25-1447 Ignacio Rodriguez Poster Presenter Spain Genome-scale screenings identify determinants of sensitivity of cancer cells and tumors to NFYA inhibition P-273 EACR25-1515 Camilla Vitali Poster Presenter Italy Putative Novel Breast Cancer Genetic Drivers in Ghana: Insights from a Cohort Study P-274 EACR25-1519 Claudia Anyigba Poster Presenter Ghana Decoding atypical teratoid rhabdoid tumor subtype-specificity: single cell aspect of differentiation trajectories and potential maturation therapy P-275 EACR25-1669 Jiayou He Poster Presenter Netherlands Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening P-276 EACR25-1673 Wei Jin Poster Presenter Australia The computational strategy, popmax, decreases misclassification of germline variants P-277 EACR25-1693 Ann Lee Poster Presenter Singapore Comprehensive analysis of somatic structural variations in Malignant pleural mesothelioma (MPM) using long-read sequencing P-278 EACR25-1713 Mazin Alhazmi Poster Presenter United Kingdom Dependency-Shock transcriptomic footprints as predictive tools in early anti-cancer drug discovery P-279 EACR25-1869 Ludovica Proietti Poster Presenter Italy Combined analysis of chromatin accessibility, promoter interactions and whole genome sequencing solved the missing heritability in gastric cancer P-280 EACR25-1879 Carla Oliveira Poster Presenter Portugal BUB1-Mediated G2/M Checkpoint Control and Mitotic Integrity: A Targetable Vulnerability in MPM P-281 EACR25-1919 Ece Cakiroglu Poster Presenter Turkey Illumina based ex situ whole transcriptome workflow providing large area capture substrate, up to 7.5 cm2 active area, and a scalable end-to-end software solution P-282 EACR25-1925 Sue Ann Molero Poster Presenter Germany A defined genomics approach for delineating the cellular states during pancreatic cancer initiation P-283 EACR25-1945 Liangru Fei Poster Presenter Norway Screening and functional characterization of small molecule compounds with selective cytotoxicity in Anaplastic Thyroid Carcinoma P-284 EACR25-1985 Ekaterina Isachesku Poster Presenter Romania Whole-genome sequencing of 122 upper urinary tract urothelial carcinomas. P-285 EACR25-2057 Yoshiaki Kurokawa Poster Presenter Japan DNA Methylation and Structural Variants in Breast Cancer: A Nanopore Sequencing Approach P-314 EACR25-2201 Bruno Costa Gomes Poster Presenter Portugal Prometastatic gene signatures of conventional and serrated colorectal carcinoma and their regulation by microenvironmental factors from primary and metastatic sites P-286 EACR25-2305 Ana Albaladejo-Gonz Poster Presenter Spain Long-Read Resequencing of Acute Myeloid Leukaemia Single-Cell RNA Sequencing Samples Improves Detection of Malignant Genomic Alterations P-287 EACR25-2363 Miche Poster Presenter Ireland Mapping immune responses to 90 cytokines in PBMCs with a 10 million cell atlas using high-throughput combinatorial single cell RNA sequencing P-295A EACR25-2415 Natalia Juiz Poster Presenter United States Transforming AI-Driven Drug Discovery with a 100 Million Single-Cell Dataset P-288 EACR25-2435 Gokhan Demirkan Poster Presenter United States Towards an Quantitative Phenotypic Progression Model of Prostate Cancer P-289 EACR25-2451 martial guillaud Poster Presenter Canada Molecular Profiling of Brain Metastases from Distinct Primary Tumors Identifies Subtypes with Implications for Therapy and Biomarker Development. P-290 EACR25-2487 Iael Weissberg Minutentag Poster Presenter Brazil Single-cell CRISPR screens: a comparative evaluation of droplet-based and combinatorial split-pool barcoding platforms P-343 EACR25-2529 Alex Chenchik Poster Presenter Exploring Alternative Splicing in Breast Cancer: Direct RNA Nanopore Sequencing for Transcriptome Profiling P-291 EACR25-2553 Susana Nunes Silva Poster Presenter Portugal Integrative analysis of epigenetic and transcriptional interrelations identifies histotype-specific biomarkers in early-stage ovarian carcinoma P-292 EACR25-2557 Hugo Swenson Poster Presenter Sweden Molecular Characterisation of Trophoblast Tumours P-293 EACR25-2563 Hannah E Crook Poster Presenter United Kingdom Clinical and Genetic Heterogeneity in Early-Onset Colorectal Cancer: Unclosing Distinct Molecular Entities P-294 EACR25-2581 Carolina Rosa Poster Presenter Portugal Multimodal analysis of spatial transcriptomics data uncovers novel invasive lobular carcinoma subtypes P-295 EACR25-2603 Matteo Serra Poster Presenter Belgium Poster and Exhibition Hall
10:45 20:00	CARCINOGENESIS Late effect of radiotherapy: impairment of DNA double-strand break repair mechanisms in skin and lung fibroblast of previously irradiated sheep P-296 EACR25-0503 Hanine Bou Hadir Poster Presenter Lebanon Secreted clusterin promotes the migration and invasion of triple-negative breast cancer cells P-297 EACR25-1013 Alessia Ciringione Poster Presenter Italy Biological relevance of the long non-coding RNA NEAT1 in Squamous Cell Carcinoma progression P-298 EACR25-1051 Sara De Domenico Poster Presenter Italy The landscape of somatic mutations in Hepatitis B virus-infected livers and its role in the origins of liver carcinogenesis P-299 EACR25-1075 Paula Otero Poster Presenter Spain Notch signaling during G2 Damage Checkpoint: a multifaced node to overcome drug resistance in T-cell acute lymphoblastic leukemia (T-ALL) P-300 EACR25-1547 Alessandra Simeone Poster Presenter Italy The Role of YWHAG Silencing in Reducing Proliferation and Migration in Glioblastoma P-301 EACR25-1647 Marta Costa Garc Poster Presenter Spain Partial inactivation of VPS34 combined with oncogenic KRAS accelerates pancreatic cancer initiation and mimics early metastasis dissemination P-302 EACR25-1773 Camille Guyon Poster Presenter France Effect of exposures to cancer risk factors on the clonal structure of normal kidney tubules P-303 EACR25-1793 Ferriol Calvet Poster Presenter Spain VPS34-driven autophagy permits cell plasticity and cancer initiation P-304 EACR25-2011 Beno Poster Presenter France Use of the novel cell division assay (CDA) to evaluate T cell toxicity in response to lutetium-177–DOTATATE peptide receptor radionuclide therapy P-305 EACR25-2015 Shaghayegh Gharaghani Poster Presenter Sweden Genomic Landscape of Skin and Internal Cancers in Xeroderma Pigmentosum Patients Reveals Signatures of Nucleotide Excision Repair Deficiency P-306 EACR25-2133 Yurchenko Andrey Poster Presenter France Secretome profiling of TNBC cells under an inflammatory condition enhances tumorigenic properties in non-tumoral breast epithelial cells P-307 EACR25-2391 Lucas Melguizo Poster Presenter Spain Poster and Exhibition Hall
10:45 20:00	DRUG RESISTANCE Adquired resistance mechanisms to KRAS G12C inhibitors in lung cancer P-308 EACR25-0003 Marc Cucurull Salamero Poster Presenter Spain Novel Topoisomerase I (Topo1) inhibitors with a non-Camptothecin core scaffold to overcome resistance to current Topo1-targeted drugs and ADCs P-309 EACR25-0051 Qun Dang Poster Presenter China Chemotherapeutic Response and Resistance in a 3D MDA-MB 231Triple-Negative Breast Cancer Spheroid Model P-310 EACR25-0163 Beynon Abrahams Poster Presenter South Africa Overcoming Gemcitabine Resistance in MDA-MB-231 Cells: A Synergistic Approach Using ABT-737 and NVP-BEZ235 Dual Inhibition of PI3K/mTOR P-311 EACR25-0209 Gizem Selimoglu Poster Presenter Turkey Bacterial modulation of 5-FU chemoresistance in head and neck cancer P-312 EACR25-0229 Lee Mai Poster Presenter Australia Investigating AMBRA1’s role as a prognostic biomarker of resistance for melanoma therapies P-313 EACR25-0247 Christina Tsiavou Poster Presenter Sweden Variable responses to Akt kinase inhibition stem from non-genetic heterogeneity P-315 EACR25-0303 Colin Ratcliffe Poster Presenter United Kingdom Acquisition of resistance to targeted therapies in lung cancer: mechanistic basis and suppressive strategies P-316 EACR25-0351 Jos Poster Presenter Portugal BET inhibitor Birabresib synergizes with PARP inhibitor Talazoparib in urothelial cancer cell lines and patient-derived organoids P-317 EACR25-0379 Jutta Schmitz Poster Presenter Germany Activation of the Integrated Stress Response to overcome multidrug resistance in cancer therapy P-318 EACR25-0505 Jorge Mota-Pino Poster Presenter Spain Targeting DUSP6 to combat therapy resistance and brain metastasis in HER2-positive breast cancer P-319 EACR25-0601 Shruti Nitin Bhardiya Poster Presenter Finland Understanding and targeting mechanisms of resistance to the cytidine deaminase biodegrader and gemcitabine combination in cancer P-320 EACR25-0637 Margot Cristol Poster Presenter France KRAS silencing impacts chromatin organization and transcriptional activity in colorectal cancer cells P-321 EACR25-0651 S Poster Presenter Portugal Characterization of TRIB2 role in pancreatic cancer chemoresistance P-322 EACR25-0659 In Poster Presenter Portugal Identifying Therapeutic Vulnerabilities in KRASG12D-Resistant Pancreatic Cancer Using High-Throughput Drug Screening P-323 EACR25-0711 Manzila Kuerbanjiang Poster Presenter Germany Potential therapeutic implication of Epithelial Protein Lost in Neoplasm (EPLIN) in head and neck cancer and chemotherapy resistance P-324 EACR25-0713 CAI WANG Poster Presenter United Kingdom Combination therapy with YAP/TEAD and RAS inhibitors overcomes phenotypic cell plasticity-driven resistance in NRAS-mutated melanoma P-325 EACR25-0739 Mira Kahil Poster Presenter France The interplay between mechanisms of resistance and therapeutic targets: identifying novel treatments for drug-resistant BRAFV600E pediatric high-grade glioma P-326 EACR25-0755 Rebecca Lehmann Poster Presenter Australia Targeting ErbB receptor family to intercept therapy adaptation in ALK-positive lung cancer P-327 EACR25-0781 JIAHAO TAO Poster Presenter Italy The Role of NRG-1 in Resistance to Targeted Cancer Therapies in ERBB2-Amplified Breast Cancer P-328 EACR25-0797 Mahtab Karbasian Poster Presenter Finland Unraveling the Hidden Player: miR-188-5p at the Crossroads of DDR and PARP Inhibitor Resistance in Ovarian Cancer P-329 EACR25-0897 Elif Merve Ayd Poster Presenter Turkey Decoding drug resistance in cervical cancer cell lines: an AKT-independent mechanism P-330 EACR25-0923 Nauf Bou Antoun Poster Presenter United Kingdom Rituximab resistance shapes sensitivity to effector-cell mediated cytotoxicity in B-cell lymphoma P-331 EACR25-0975 Aleksandra Maria Kusowska Poster Presenter Poland Crosstalk between oncogenic signaling pathways as driver of therapy resistance against small molecule inhibitors in Glioblastoma P-332 EACR25-0987 Mike van Heumen Poster Presenter Netherlands Targeting Drug Resistance in Hepatocellular Carcinoma: Uncovering Metabolic Vulnerabilities for Therapeutic Re-Sensitization P-333 EACR25-1015 Dzeneta Halilovic Poster Presenter Luxembourg Investigating estrogen receptor fusion proteins as a mechanism of resistance to endocrine therapies in breast cancer P-334 EACR25-1057 Anastasia Alataki Poster Presenter United Kingdom Increased Sensitivity to BCL-2 Inhibition in EGFR-TKI Resistant NSCLC Cell Lines P-335 EACR25-1105 Madeleine Jares Poster Presenter Germany SPOCK1 is Linked to Mesenchymal-like Features and Drug Resistance in Melanoma Cells Treated with BRAF and MEK Inhibitors P-336 EACR25-1107 Carme Sol Poster Presenter Spain Combinatorial assessment of DXd-based antibody drug conjugates with DNA damage response inhibitors in ovarian and endometrial cancers P-337 EACR25-1127 Yongda Li Poster Presenter Ireland Unraveling Therapeutic Resistance in Patients with Early-Stage HER2-Negative Breast Cancer in the I-SPY2 Clinical Trial P-338 EACR25-1205 Tam Binh Bui Poster Presenter United States Pt1a and sorafenib combination treatment exerts synergistic anti‑hepatocellular carcinoma effect through RNA m6A methylation modification P-339 EACR25-1273 Yinjia Huang Poster Presenter Hong Kong, China SOAT1 Promotes Methotrexate Resistance in Choriocarcinoma P-340 EACR25-1275 Mengxia Zheng Poster Presenter China Creating Repotrectinib Resistance in a Ba/F3 SLC34A2-ROS1 NSCLC cell line P-341 EACR25-1297 Patrick Korthuis Poster Presenter Netherlands Targeting Fascin as a Therapeutic Approach to Overcome Oxaliplatin Resistance in Colorectal Cancer P-342 EACR25-1307 Diogo Rafael Da Cruz Ribeiro Poster Presenter Spain SRSF9-mediated alternative splicing impairs anti-tumor immunity and drives resistance to PD-L1/VEGF-A blockade in hepatocellular carcinoma P-344 EACR25-1407 Jie Luo Poster Presenter Hong Kong, China Revealing Distinct Oxaliplatin Resistance Mechanisms in HCT116 Cells Through Genomic and Transcriptomic Analysis Under Continuous and Intermittent Treatment Regimens P-345 EACR25-1413 Gamze Yilmaz Poster Presenter Turkey An unbiased in vitro screen for uncovering HER2 drug resistance mutations P-346 EACR25-1461 Iman Farahani Poster Presenter Finland Quantitative proteomics of drug-metabolizing enzymes and transporters in patients with appendix tumours P-347 EACR25-1467 Areti-Maria Vasilogianni Poster Presenter United Kingdom Establishment of chemoresistant patient-derived tumor organoids (PDTO) to identify relevant biomarkers for second-line treatments in ovarian cancer P-348 EACR25-1477 Sahra Messaoudi Poster Presenter France Lysosomal Ca2+ release via TRPML3 enhances drug sensitivity of gefitinib-resistance NSCLS cells P-349 EACR25-1569 Sei-Hoon Yang Poster Presenter Korea (Republic of) SOS1 inhibition enhances the efficacy of and delays resistance to oncogene-targeted therapies in lung adenocarcinoma P-350 EACR25-1617 Robert L Kortum Poster Presenter United States INTRINSIC MECHANISMS OF RESISTANCE TO CDK4/6 INHIBITORS IN LUMINAL METASTATIC BREAST CANCER P-351 EACR25-1655 Maribel Aybar Molina Poster Presenter Spain Overcoming Antibody-Drug Conjugate Resistance in HER2-Positive Breast Cancer: Insights into Molecular Mechanisms and Targeted Therapeutic Approaches P-352 EACR25-1689 Queenie Yong Poster Presenter New Zealand Chlorpromazine nanoparticles enhance anti-cancer effect of Doxorubicin nanoparticles preventing their extrusion P-353 EACR25-1707 Abhisek Mishra Poster Presenter India Involvement of Androgen Receptor/miR-181a-5p/c-Met Axis in the Progression of Prostate Cancer P-354 EACR25-1709 Peyda Korhan Poster Presenter Turkey miR-212-3p Down-Regulates the MAPK/ERK Pathway to Mitigate Oxaliplatin Resistance in Colorectal Cancer P-355 EACR25-1715 Tsai-Yi Hsu Poster Presenter Taiwan Functional and molecular changes implicated in doxorubicin resistance in breast cancer P-356 EACR25-1777 Lenka Trnkova Poster Presenter Slovakia Sensitization of ovarian cancers to ΡARΡ inhibitors by inductiοn of an ΗRD phenοtype: towards a medicine of precision based on UBE2Ν inhibitiοn. P-357 EACR25-1781 L Poster Presenter France A not expected effect of longterm temozolomide treatment on resistance of glioblastoma cells – an in vitro study P-358 EACR25-1827 Claudia von Montfort Poster Presenter Germany Intercellular Communication via Therapy-Induced Secretome Drives Chemoresistance in Ovarian Cancer Cells P-359 EACR25-1885 Polina Shnaider Poster Presenter Russia On-target mutations confer resistance to WRN helicase inhibitors in Microsatellite Unstable Cancer Cells. P-360 EACR25-1893 GABRIELE PICCO Poster Presenter United Kingdom The Role of AP-1 Target Transcript Vav3.1 in the Regulation of Osimertinib Resistance in Lung Adenocarcinoma P-361 EACR25-1999 Nazife Ege G Poster Presenter Turkey Unravelling PARP inhibitor resistance mechanisms in ovarian cancer P-362 EACR25-2027 Adri Poster Presenter Spain Identifying miR-7-5p/KEAP1/NRF2 and miR-122-5p/ADAM10/IL-6 signaling axes in Castration and Enzalutamide-resistant prostate cancer cells P-363 EACR25-2033 Ceyda Nur Zaim Poster Presenter Turkey Targeting ferroptosis resistance by inhibiting SCD1 in TNBC enhances tumor response to immunotherapy. P-364 EACR25-2063 Quentin Herrera Garfia Poster Presenter Belgium Tumor microenvironment determines immune resistance to chemoimmunotherapy in KRAS-mutant Non-Small Cell Lung Cancer: transcriptomic insights from a prospective cohort P-904 EACR25-2083 Raquel Herrero Poster Presenter Spain Targeting BCL-2 proteins as a Strategy Against Therapy Persistency in TNBC P-365 EACR25-2121 T Poster Presenter Spain Targeting Epigenetic Mechanisms to Overcome Drug Resistance in TaxaPlatin-Resistant Prostate Cancer P-366 EACR25-2193 Neslihan Y Poster Presenter Turkey CDK12/13 inhibition can counteract Epithelial Ovarian Cancer chemoresistance P-367 EACR25-2239 Ilenia Pellarin Poster Presenter Italy High resolution profiling of complex in vitro 3D lung cancer model to monitor resistance to immune checkpoint inhibitors P-368 EACR25-2279 Hortense PERDRIEAU Poster Presenter France EGFR/SHP2-targeted antibody-drug conjugate for colorectal cancer theranostics P-369 EACR25-2319 Joana Filipa Santos Poster Presenter Portugal Overcoming PARP inhibitor resistance in ovarian cancer: interest of the HDAC inhibitor belinostat P-370 EACR25-2375 Sterenn Guillemot Poster Presenter France Reducing Glioblastoma Treatment Heterogeneity Through Tumor Treating Fields Application Coupled With tmCLIC1 Impairment by Metformin P-371 EACR25-2407 Michele Mazzanti Poster Presenter Italy Cisplatin resistance hinders the response to CDK4/6 inhibitors in esophageal squamous cell carcinoma cells P-373 EACR25-2503 Marta Avalos Moreno Poster Presenter Belgium Targeting AURKA Overcomes Gemcitabine Resistance in TP53-Mutated Cancers by Disrupting the Replication Stress Response P-374 EACR25-2593 Jian Wang Poster Presenter China Poster and Exhibition Hall
10:45 20:00	EPIGENETICS RASSF1A Methylation and Survival Outcome in Retroperitoneal Leiomyosarcoma P-375 EACR25-0049 Michael Wong Poster Presenter United Kingdom Investigating the influence of copper homeostasis on epigenetic modulation in the tumour microenvironment P-376 EACR25-0077 Giulia Castrogiovanni Poster Presenter Australia Deciphering the epigenetic de-regulation of the stem cell related HOX signature in glioblastoma P-377 EACR25-0181 Davide Chiesi Poster Presenter Switzerland Boosting Pancreatic Cancer Treatments: overcome chemoresistance by targeting N6 methyladenosine modification P-378 EACR25-0273 Chiara Reina Poster Presenter Italy The epigenetic regulator TRIM24 controls melanoma cell dedifferentiation and resistance to treatment in melanoma P-379 EACR25-0329 Julie CARAMEL Poster Presenter France Defining the Epigenetic Landscape regulating a Progenitor Signature in Development and, during Tumour Initiation and Progression P-380 EACR25-0365 Martina Bellafante Poster Presenter Italy Identification of epigenetic drivers in colorectal cancer from clinical tissue and blood samples P-381 EACR25-0465 Aniruddha Chatterjee Poster Presenter New Zealand Multiomics 6-base sequencing enhances the performance of early colorectal cancer detection from cell-free DNA P-382 EACR25-0613 Tom Charlesworth Poster Presenter United Kingdom MicroRNA-Driven Modulation of TACSTD2 (TROP2) in Colorectal Cancer Progression P-383 EACR25-0629 Irmak G Poster Presenter Germany The CTCF - H3K27 methylation axis supports the migration of melanoma cells by regulating cholesterol biosynthesis P-384 EACR25-0735 Gabi Gerlitz Poster Presenter Israel Targeting the chromatin remodeler HELLS to Improve Therapeutic Strategies in T-Cell Lymphoma P-385 EACR25-0777 Giulia Gambarelli Poster Presenter Italy Single-Cell Analysis of Epigenetic Landscapes Highlights Recurrent Chromatin Accessibility Alterations in Colorectal Cancer P-386 EACR25-0989 Alexandra Livanova Poster Presenter Italy Epigenetic changes on the X chromosome in chronic lymphocytic leukaemia P-387 EACR25-1097 Timothy Barrow Poster Presenter United Kingdom Higher global DNA methylation levels in tumoral tissue from Mexican patients with Prostate Cancer with different Gleason score P-388 EACR25-1181 Ana Karen Flores Islas Poster Presenter Mexico Glucagon-like Peptide-1 Receptor involvement in breast cancer progression is regulated by epigenetic mechanisms P-389 EACR25-1489 Virginia Vigiano Benedetti Poster Presenter Italy LACTB Promotes SHMT2 Degradation, Modulating Glycine Metabolism and DNA Methylation Patterns in Breast Cancer Cells P-390 EACR25-1867 Gabriel Miguel Rodriguez Gomez Poster Presenter Czech Republic Hsa-miR-200c-3p, hsa-miR-25-3p and hsa-miR-301a-3p as potential biomarkers and therapeutic targets for restoration of PTEN expression in clear cell renal cell carcinoma P-391 EACR25-1905 Poster Presenter Portugal Integrated analysis of longitudinal cell-free DNA and matched tumor profiling data to identify novel breast cancer biomarkers P-392 EACR25-1943 Daniyar Karabayev Poster Presenter Finland Hypermethylation of extracellular matrix genes in colorectal adenocarcinoma P-393 EACR25-2049 Dalma M Poster Presenter Hungary SUV39H1 regulates cell adhesion of pediatric high-grade gliomas through modulation of β-catenin P-394 EACR25-2159 Christos Adamopoulos Poster Presenter Greece Methylation-driven epigenetic regulation of the MIR141 core promoter in bladder cancer short-term progression P-395 EACR25-2261 Margaritis Avgeris Poster Presenter Greece Exploiting the tumor-suppressive role of the transcriptional repressor SAMD1 in pancreatic ductal adenocarcinoma P-396 EACR25-2323 Lea Marie Jeude Poster Presenter Germany Investigating the tumor-suppressive role of the transcriptional co-repressor IRF2BP2 in pancreatic ductal adenocarcinoma P-397 EACR25-2545 Theresa Sofie Huber Poster Presenter Germany Poster and Exhibition Hall
10:45 20:00	EXPERIMENTAL / MOLECULAR THERAPEUTICS, PHARMACOGENOMICS Preventive and Therapeutic Effects of Amaranthus hybridus and Corchorus olitorius on Breast Cancer P-398 EACR25-0009 Emeka Eze Joshua Iweala Poster Presenter Nigeria Phage display identified claudin 18.2 binding peptide for early pancreatic diagnosis and tumor-target killing. P-399 EACR25-0047 Poongkavithai Vadevoo Sri Murugan Poster Presenter Korea (Republic of) Nanobody-PROTACs: Method development towards the use of single-domain antibody proteolysis-targeting chimera constructs (sdAb-PROTACs) to target 'undruggable' proteins for degradation P-400 EACR25-0065 Caroline Hannah Cope Poster Presenter United Kingdom Impact of immune checkpoint inhibitors (ICIs) alone or combined with chemotherapy (ICI/chemotherapy) on the prognosis of non-small cell lung cancer (NSCLC) patients with high expression of programmed P-401 EACR25-0085 Jin Gu Chen Poster Presenter China A potential nanocarrier for Androgen-resistant in prostate cancer: Green synthesis of ZnO nanoparticle P-402 EACR25-0087 Ms. Salida Ali Poster Presenter Preclinical Evaluation of RAS(ON) Multi-Selective Inhibitors as a Therapeutic Strategy for KRAS mutant Cholangiocarcinoma P-403 EACR25-0175 Konstantina Morali Poster Presenter Spain Development and Validation of a Novel Multi-Functional Iron Oxide Nanoparticle for the Targeted Induction of Ferroptosis in Cancer P-404 EACR25-0295 Darius McPhail Poster Presenter United Kingdom Innovative Cyclic Peptide Disrupts IL-17RB/MLK4 Interaction for Targeted Pancreatic Cancer Therapy P-405 EACR25-0301 Chun-Mei Hu Poster Presenter Taiwan Rationally designed cholesterol-coated peptide nanosponges as a novel therapeutic strategy in the management of Adrenocortical Carcinoma P-406 EACR25-0375 Mariam Hassany Poster Presenter Ireland Targeting Estrogen-Related Receptor Gamma (ERRγ) in Ovarian Carcinoma: Therapeutic Potential of DN200434 and MK2206 Combination in-vitro and in-vivo P-407 EACR25-0411 Deepak Gulwani Poster Presenter India canSERV – providing cutting edge cancer research services across Europe P-408 EACR25-0521 Manuela Pausan Poster Presenter Austria Targeting PDGFRA in Pediatric High-Grade Gliomas: Insights from Brazilian Preclinical Models P-409 EACR25-0539 Mirella Baroni MIlan Poster Presenter Brazil Patient-Derived Glioma Organoids Resist Standard Therapies but Respond to Targeted Inhibition P-410 EACR25-0549 Alvaro Monago S Poster Presenter Spain Combining in silico and in vitro approaches to repurpose candidate drugs for oral squamous cell carcinoma P-411 EACR25-0559 Marina Silva Rodrigues de Souza Poster Presenter Brazil Glioma Targeting Peptide-Drug Conjugates: Comparative in vitro and in vivo evaluation P-427B EACR25-0569 Ivan Randelovic Poster Presenter Hungary Anti-cancer effects of Amiodarone via cell cycle arrest, mitochondrial dysfunction, excessive autophagy, and increased apoptosis in thyroid cancer cells P-412 EACR25-0623 Seunghyeon Ahn Poster Presenter Korea (Republic of) UD-086 overcomes trastuzumab deruxtecan-resistance and has a best-in-class therapeutic index in MMAE-based antibody drug conjugates P-413 EACR25-0627 Naoya Oishi Poster Presenter Japan SELECTIVE DEGRADATION OF MLK3 BY NOVEL CEP1347-VHL-02 PROTAC COMPOUND LIMITS ONCOGENIC POTENTIAL OF TNBC P-414 EACR25-0653 Kamila Karpinska Poster Presenter Poland EZH2 inhibitors dramatically sensitize breast cancers to HER2 kinase inhibitors through cooperative effects on YAP and pro-apoptotic regulators P-415 EACR25-0667 Naiara Perurena Poster Presenter United States Pre-clinical Evidence for Ivacaftor as a Potential Repurposed Therapy for High-Grade Serous Ovarian Cancer and Endometrial Cancer P-416 EACR25-0683 Dongli Liu Poster Presenter Australia Synergistic antineoplastic Effects of Jania rubens Extracts with Conventional Chemotherapy in Colorectal Cancer. P-417 EACR25-0701 Zeina Tarek Dassouki Poster Presenter Lebanon 1959-sss/DM4 Antibody-Drug Conjugate targeting extracellular LGALS3BP Exhibits Potent Antitumor Activity in orthotopic Glioblastoma Models P-418 EACR25-0709 Emily Capone Poster Presenter Italy Bufalin Targets Protein Translation and Cell Metabolism to Overcome Therapy Resistance in Melanoma P-419 EACR25-0741 Aline Genbauffe Poster Presenter Belgium FAM46C expression sensitizes multiple myeloma cells to PF-543-induced cytotoxicity P-421 EACR25-0779 Ivan Ferrari Poster Presenter Italy An intracellular cytidine deaminase biodegrader to overcome cancer chemoresistance P-422 EACR25-0795 Marie SORBARA Poster Presenter France dTAG-based degradation of CDK5 as a therapeutic strategy in colorectal cancer P-423 EACR25-0823 Ferran Grau Leal Poster Presenter Spain Multiomic characterization and high-throughput drug testing of patient-derived NSCLC organoids P-424 EACR25-0863 Azadeh Motavallian Poster Presenter Germany Sesquiterpene Lactones Cynaropicrin and Ludartin as Potential Therapeutic Agents in Ovarian Cancer P-425 EACR25-0867 Arya Akda_ Poster Presenter Turkey Unlocking the Therapeutic Potential of Platelets in B-Cell Malignancies – Preliminary Study P-426 EACR25-0883 Joana Jorge Poster Presenter Portugal Designer proteins to drive the targeted degradation of tankyrase P-427 EACR25-0889 Huey Ying Kok Poster Presenter United Kingdom Alectinib enhances response to RBM39 degradation via SRPK1 inhibition in high-risk neuroblastoma P-427A EACR25-0895 Yurui Ma Poster Presenter United Kingdom Targeting MYC as a promising therapeutic strategy for pediatric medulloblastoma P-428 EACR25-0925 Laura Escudero Poster Presenter Canada Optimizing Gemcitabine Delivery: HPMA Copolymer Conjugates with Controlled Drug Release and Immunomodulatory Activity P-430 EACR25-0983 Kate_ina B_halov Poster Presenter Czech Republic Discovering ERBB signaling as therapeutics target for β-catenin mutation driven hepatocellular carcinoma using mouse organoid platform P-431 EACR25-0993 Tin Lok WONG Poster Presenter Hong Kong, China CircRNA-mediated inhibition of miRNA-454 as a novel therapeutic strategy in prostate cancer P-432 EACR25-1025 Achim Aigner Poster Presenter Germany Preclinical Evaluation of T-DXd and AZD1390 in HER2-Low, Triple-Negative Breast Cancer Models P-433 EACR25-1129 Larissa Bless Poster Presenter Ireland Reactivating the crosstalk between natural killer and tumour cells in non-small cell lung cancer (NSCLC) patients with no actionable mutations P-434 EACR25-1165 Cavassi Elena Poster Presenter Italy Harnessing the impacts of a G-quadruplex ligand in liposarcoma: Implications for MDM2 oncogene targeting and DNA damage-mediated immunomodulatory effects P-435 EACR25-1173 Eisa Naghshineh Poster Presenter Italy Synthetic Danshen Compound Inhibits Adipogenesis, Promotes Adipocyte Browning, and Induces G1 Cell Cycle Arrest While Suppressing Tumor Cell Migration and Invasion in Prostate Cancer Cells P-436 EACR25-1193 Ching-Feng Cheng Poster Presenter Taiwan Investigating BCL3 as a therapeutic target to treat prostate cancer P-437 EACR25-1285 Marcos Quintela-Vazquez Poster Presenter United Kingdom The RUVBL1/2 Complex: An Actionable Molecular Target in Bladder Cancer P-438 EACR25-1321 Buse Akdemir Poster Presenter Turkey Cold-pressed lingonberry (Vaccinium Vitis-Idaea) extract inhibits proliferation, invasion and glycolysis of oral carcinoma cells P-439 EACR25-1325 Tuulia Onali Poster Presenter Finland Discovery of a novel 1,2-epoxysteroid oxime with potent anti-pancreatic cancer activity P-440 EACR25-1327 Maria Filomena Botelho Poster Presenter Portugal Unveiling the Therapeutic Potential of Tick Salivary microRNAs in Cancer Treatment P-441 EACR25-1329 Juan Antonio Marchal Poster Presenter Spain Boronated derivatives with a carborane cage, sulfamido group, and Gd-DOTA for B/Gd-NCT with Carbonic Anhydrase IX inhibition. P-442 EACR25-1331 Sahar Rakhshan Poster Presenter Italy Investigating the cytotoxic effects of rhenium (V) complexes with apigenin and derivatives P-443 EACR25-1333 Ana Radovan Kandi_ Poster Presenter Serbia Arginine deprivation, mTOR signalling and DNA repair response in models of ovarian cancer P-444 EACR25-1347 Laila Cedra Evangelista Poster Presenter United Kingdom Co-targeting of EGFR and Sp1 to inhibit TKIs resistance and improve immune response in NSCLC tumors P-445 EACR25-1359 Francesca Iommelli Poster Presenter Italy Characterisation of bicyclic drug conjugate tool molecules using complementary 2D and 3D cellular models in vitro P-446 EACR25-1363 Jennifer Bre Poster Presenter United Kingdom Diphyllin, a SPP1/DKK1 inhibitor, restricts hepatocellular carcinoma growth by modulating sugar and bile acid metabolism P-447 EACR25-1373 Jinfang Zhang Poster Presenter China Transcriptional profiling and ex vivo drug pre-screen for personalized therapy selection P-448 EACR25-1419 Audrey Gal Poster Presenter Switzerland Remodeling the Tumor Microenvironment through TSP-1/CD47 Antagonization: Non-Clinical Characterization of the TAX2 drug candidate P-449 EACR25-1421 Aur Poster Presenter France A Novel High-Throughput Assay for Targeted Protein Degradation: Application to BCL-xL in Cancer Cells P-450 EACR25-1429 DANIELE CARETTONI Poster Presenter Italy Novel Titanocene-derived complex with high albumin affinity: Evaluation of antitumor activity in ovarian cancer cells P-451 EACR25-1449 Virginia Pérez Garrido Poster Presenter Spain Lysosomal Stress as an Off-target Effect of UNC0642 in Pancreatic Cancer Cells P-452 EACR25-1465 Ana Clara Albuquerque Poster Presenter United Kingdom Development of GD2-Targeted Herpes simplex vectors for OncoVirotherapy P-453 EACR25-1553 Alessandra Napolano Poster Presenter Italy Therapeutic deep eutectic systems as promising selective therapeutic agents in the anticancer battle P-454 EACR25-1579 Filipe Oliveira Poster Presenter Portugal Identification and Validation of new In-Silico Designed MYC Binders P-455 EACR25-1583 Janice Wenzheng Neng Poster Presenter United Kingdom Investigation of novel anti-leukemic compounds uncovered through high-throughput screening of human model leukemias P-456 EACR25-1585 Karla Lucia Paez Martinez Poster Presenter Canada Potential of inhibition of AR to enhance the sensitivity of OVCAR-3 cells to PARP inhibitor P-458 EACR25-1595 Nevenka Gligorijevic Poster Presenter Serbia Targeting Invasive Behavior in 2D, 3D, and In Vivo Models with Pentamethinium Salts as Migrastatic Agents P-459 EACR25-1691 Katerina Petrlakova Poster Presenter Czech Republic Rhenium Complexes as Promising Selective Anticancer Agents P-460 EACR25-1725 Anna Pogorzelska Poster Presenter Poland Mechanism of Action of DNA Polymerase Inhibitors in Triple-negative Breast Cancer Cells and Anti-tumor Effects in an Intraductal Breast Cancer Mouse Model P-461 EACR25-1733 Nadine Darwiche Poster Presenter Lebanon Targeting RSK1 in Colon Cancer: Discovery and Evaluation of a New Small Molecule Inhibitor P-462 EACR25-1745 Ufuk Mulhim Poster Presenter Turkey Mitochondrial Transplantation from Oxidatively Stressed Adipocyte-Derived Mitochondria Induces Ferroptosis in Glioblastoma P-463 EACR25-1751 Junbo Liao Poster Presenter Hong Kong, China Patient-Derived 3D metastatic melanoma models for target discovery and personalized therapy P-464 EACR25-1779 Anshika Katyal Poster Presenter Israel Pan-cancer therapy using oncofetal-chondroitin sulfate targeting antibody-drug-conjugates P-465 EACR25-1795 Elena Vidal-Calvo Poster Presenter Denmark EGFR targeting restores primary cilia loss upon ETS-driven oncogenic transformation in prostate cells P-466 EACR25-1803 Sofia Oliveira Costa Poster Presenter Portugal Combination of cerium oxide nanoparticles and antimalarial drug chloroquine: characterization and anti-cancer potential for triple negative breast cancer P-467 EACR25-1843 Chantal-Kristin Wenzel Poster Presenter Germany The role of drug efflux and uptake transporters in the plasma and tissue disposition of KRASG12D inhibitor MRTX1133 P-468 EACR25-1851 Davinia Arguedas Poster Presenter Netherlands Identification of a new ERK5 kinase inhibitor P-469 EACR25-1863 Ylenia Sfragano Poster Presenter Italy Dual-Active Peptides: A Promising Therapy for Brain Metastases P-470 EACR25-1887 Vera Neves Poster Presenter Portugal Optimization of Bivalent Immunoliposome Preparation for Selective Cytotoxic Activity Against Triple-Negative Breast Cancer Cells P-471 EACR25-1899 Ma_gorzata Milczarek Poster Presenter Poland The development of a USP7 inhibitor for cancer immunotherapy P-472 EACR25-1913 Angelika Muchowicz Poster Presenter Poland Isolation of anti-proliferative bioactive compounds from Gypsophila erocalyx plant extracts by activity-guided approach and its activity in prostate cancer P-473 EACR25-1971 B Poster Presenter Turkey Synergistic effect of 5-fluorouracil and the small molecule Wnt/ P-474 EACR25-2017 Maren Smarslik Poster Presenter Germany Identification of HMGA protein inhibitors as potential cancer therapy P-475 EACR25-2087 Sabrina Battista Poster Presenter Italy Idasanutlin in combination with PD-1 blockade - synergy or antagonism? P-476 EACR25-2115 Lukasz Skalniak Poster Presenter Poland Multiparametric Analysis of High-Throughput 3D Imaging-Based Drug Screening Reveals Cancer Drug-Induced Vulnerabilities in Patient-Derived Metastatic Colorectal Cancer Organoids P-477 EACR25-2119 Gizem Damla Yal Poster Presenter Turkey Celastrol induces pro-apoptotic and anti-migratory effects against medulloblastoma subtypes P-478 EACR25-2123 Julia Morovis Marchetti Cassarotti Poster Presenter United Kingdom Localized Drug Delivery for Cachexia-inducing Tumors: Overcoming Systemic Treatment Challenges P-478A EACR25-2171 Vito Telebar-Zbulj Poster Presenter Austria Nanocarriers for Targeted Boron Delivery to Tumor Cells in BNCT Applications P-479 EACR25-2245 Julieta Nicole Pi Poster Presenter Italy Antitumor immune mechanisms elicited by NLRC5 expression in cancer cells P-480 EACR25-2253 Sheela Ramanathan Poster Presenter Canada Preclinical validation of a promising protein-protein interaction peptide inhibitor towards metastatic breast cancer P-481 EACR25-2293 Marco Cavaco Poster Presenter Portugal Development of an optogenetic lytic system in E.coli based on phage-derived lytic proteins as a light-controlled and safe drug delivery platform. P-482 EACR25-2303 Annapaola Petrosino Poster Presenter Italy Triptolide induces pro-apoptotic effects against medulloblastoma subtypes P-483 EACR25-2325 Hannah Eastham Poster Presenter United Kingdom Identifying on-target and off-target effects of hundreds of oncology drugs in PRISM large-scale cell line profiling with machine learning analysis of baseline and functional genomic features P-484 EACR25-2329 Jennifer Roth Poster Presenter United States Assessment of novel therapeutic treatments in KRAS mutant Colorectal Cancer using Patient-Derived Organoids P-485 EACR25-2331 Melania Lazzari Poster Presenter Italy Evaluation in vitro and in vivo of the therapeutic effect of the melatonin-furanochalcone hybrid in colorectal cancer P-486 EACR25-2371 Vanesa Bedoya Poster Presenter Colombia Anagrelide induced remodeling of the PDE3-SLFN12 interactome provides insights into translation initiation dynamics and molecular glue mechanisms P-487 EACR25-2381 Sami Ilmari Salmikangas Poster Presenter Finland Antitumoral compounds: a nutraceutical approach in cancer therapy P-488 EACR25-2443 Antonella cusimano Poster Presenter Italy Comparative analysis of proteomics and transcriptomics in patient-derived tumoroids for precision oncology and drug discovery P-489 EACR25-2475 Sara P Poster Presenter Spain Coffee Exosomes Have Distinct Effects on Melanoma and Glioblastoma Cancer Cells via PTEN Tumor Suppressor Protein P-490 EACR25-2477 Ela Doruk Korkmaz Poster Presenter Turkey Highly-targeted personalised siRNAs for BRAF-fusions inhibit melanocytic proliferation P-491 EACR25-2497 Sara Barberan Martin Poster Presenter United Kingdom Evaluation of pleural mesothelioma sensitivity to targeted DNA damage response inhibitors P-492 EACR25-2499 FARIHA IDREES Poster Presenter Italy Preclinical Evaluation of Novel Phosphoinositide 3-Kinase Inhibitors: Antitumor Activity and Toxicity Assessment P-493 EACR25-2559 Renato Jos Poster Presenter Brazil Isothiocyanate-derived mercapturic acids potentiate tubulin polymerization inhibitors anticancer activity in urinary bladder cancer models (in vitro and in vivo studies) P-494 EACR25-2601 Mateusz Psurski Poster Presenter Poland Poster and Exhibition Hall
10:45 20:00	IMMUNOTHERAPY Nanobodies against PSMA as the foundation for new tracers for prostate cancer imaging and treatment P-495 EACR25-0109 Tong Yang Poster Presenter Netherlands Scoparone attenuates PD-L1 expression in human breast cancer cells by MKP-3 upregulation P-497 EACR25-0203 Hong Seok Kim Poster Presenter Korea (Republic of) Exercise to boost the immune system and optimise immunotherapy responsiveness in pancreatic cancer P-498 EACR25-0279 Brindley Hapuarachi Poster Presenter United Kingdom Epigenetic Modulation of CAR-T cells against Group 3 Medulloblastoma P-499 EACR25-0289 Song San Chan Poster Presenter United Kingdom Unveiling interactions between senescent tumor cells and the host immune system - Implications for Senolytic Immunotherapy P-500 EACR25-0347 Bartolomeo Bosco Poster Presenter Germany Investigating the repurposing potential of immune checkpoint inhibitors to additional cancer patient populations using Mendelian randomisation P-501 EACR25-0435 Tessa Bate Poster Presenter United Kingdom Assessing the Potential of Epigenetic Inhibitors to Improve Immunotherapy Response via In Vitro Models P-502 EACR25-0481 Manuel Pino Gonz Poster Presenter Spain Bacterial Endospores as Antigen Carriers: A Novel Strategy for Cancer Vaccines P-901 EACR25-0671 Lourenço Cayolla Bonneville Poster Presenter Italy Next Generation Protein Characterization of CD19-CAR Signaling Cascades P-503 EACR25-0825 Warren Higgs Poster Presenter United Kingdom The effect of STING agonist on lung metastases and immune landscape in murine model of spontaneous breast cancer metastasis P-504 EACR25-0955 Alina Drzyzga Poster Presenter Poland Pioneer Platform: A Novel Biotherapeutic Antibody Discovery Platform P-505 EACR25-1001 Paola Genevini Poster Presenter Italy Understanding bystander killing by bispecific monoclonal antibodies P-506 EACR25-1143 May Sin Ke Poster Presenter United Kingdom A novel synthetic peptide HS1002 Enhances T Cell-Mediated Antitumor Immunity P-507 EACR25-1203 Jae Hyeon Park Poster Presenter Korea (Republic of) Induction of TWIST1-specific antitumor immunity by DNA vaccine encoding a truncated TWIST1 antigen P-508 EACR25-1425 Zhiwu Tan Poster Presenter Hong Kong, China mRNA Cancer Vaccines: Leveraging Sugar-Functionalized LNPs for Targeted Antitumor Immunity P-509 EACR25-1491 Jo Poster Presenter Portugal Characterization of radiolabelled single-domain anti-HER2 antibodies as potential radioimmunotherapeutics for breast cancer P-510 EACR25-1577 Zuzanna Napora Poster Presenter Poland Glycopolymer-Mediated Gene Delivery for Efficient CAR-T Cell Production P-511 EACR25-1641 Diana Pinheiro Correia Poster Presenter Portugal Cellular Composition and Dynamics Upon Immunotherapy Correlate with Clinical Response P-512 EACR25-1649 Zhongyang Lin Poster Presenter Israel Redox-Responsive Self-Immolative Nanogels for Cellular Immunotherapies P-513 EACR25-1671 Diana Pinheiro Correia Poster Presenter Portugal Development of PD-L1 based cancer vaccine conjugating a novel T cell epitope P-514 EACR25-1699 Tomoyuki Nishikawa Poster Presenter Japan Selection and identification of nanobodies against a cancer-testis antigen, placenta-specific protein 1 P-515 EACR25-1757 Phakjira Tiraratchailert Poster Presenter Thailand Patient-derived tumor tissue cultures (PDTTCs) as a new platform for assessing T cell engager efficacy in glioblastoma. P-516 EACR25-1815 Raffaella Iurlaro Poster Presenter Spain ENO3PEP vaccine enhances chemotherapy efficacy in pancreatic cancer by boosting anti-tumor immunity P-517 EACR25-1817 Silvia Brugiapaglia Poster Presenter Italy Enhanced natural killer cell anti-tumor activity with Erastin mediated ferroptosis and potential therapeutic application in neuroblastoma. P-518 EACR25-1823 Ganesh Umapathy Poster Presenter Sweden An innovative immune-on-chip platform for studying tumor-immune interactions and evaluating novel immunomodulatory therapies P-519 EACR25-1849 SILVIA SCAGLIONE Poster Presenter MicroRNAs humoral and cellular immune response profile to COVID-19 vaccine boost in cancer patients P-907 EACR25-1881 Tânia Rôlo Dias Poster Presenter Portugal The immune and metabolic profile in metastatic and early-stage triple negative breast cancer patients treated with immune checkpoint inhibitors. P-520 EACR25-1935 Luc Poster Presenter Spain Exploring CAR-T Cell Killing Dynamics Through Live-Cell Fluorescence Microscopy P-521 EACR25-1965 Svenja Meiler Poster Presenter Characterization of Different CAR Architectures Harboring the Murine GD2 Binder 14G2a P-521A EACR25-1987 Ines del Rincon Poster Presenter Germany Cytotoxic ILC-1 cells determine outcome of PD-(L)1 blockade in microsatellite instable cancers P-522 EACR25-2039 Paula Van Royen Poster Presenter Netherlands Visualization and quantification of antibody-dependent cellular phagocytosis (ADCP) using a live-cell imaging high-throughput automation system P-523 EACR25-2051 Reinhild Geisen Poster Presenter Germany Distinct chemotherapy regimens differentially modulate the immune landscape of triple-negative breast cancer, with potential impact on combination with immunotherapy P-524 EACR25-2225 Marco Barreca Poster Presenter Italy Inhibition of Furin in CAR macrophages directs them toward a proinflammatory phenotype and enhances their antitumor activities P-525 EACR25-2299 Lydia Ziane Chaouche Poster Presenter France A positive crosstalk between chemokine receptor CXCR4 and intrinsic programmed cell death-1 receptor (iPD-1): anti PD-1, nivolumab, impairs CXCL12-induced signaling, proliferation and migration in human colon cancer cells P-526 EACR25-2311 Caterina Ieran Poster Presenter Italy Combining NK/CAR-NK-based therapy with autophagy inhibition as therapeutic strategy in high-risk medulloblastoma P-527 EACR25-2321 Manuela Giansanti Poster Presenter Italy Anti-IL-7Rα antibodies: a targeted therapy for T-cell Acute Lymphoblastic Leukemia P-528 EACR25-2349 Mafalda Dias Duque Poster Presenter Portugal Improving Triple-Negative Breast Cancer immunogenicity via viral-mediated epigenetic remodeling P-529 EACR25-2457 Salvatore Russo Poster Presenter Finland Advancing CAR-T clinical development with high-parameter CyTOF technology P-530 EACR25-2549 Melissa Klug Poster Presenter Poster and Exhibition Hall
10:45 20:00	MOLECULAR AND GENETIC EPIDEMIOLOGY Application of Mendelian randomization to appraise causality of the relationship between the gut microbiome and cancer P-531 EACR25-0385 Amy Charlotte Dawes Poster Presenter United Kingdom Malignancies of the small intestine: incidence and trends in a nationwide registry. P-532 EACR25-0531 Pascale Schafrat Poster Presenter Netherlands Exploring circulating proteins as intermediates between physical activity and cancer risk P-533 EACR25-1041 Lucy Goudswaard Poster Presenter United Kingdom Time to diagnosis for ovarian cancer in England: Associations with ‘alternative explanation’ comorbidities and recent menopause P-534 EACR25-1151 Anjum Memon Poster Presenter United Kingdom Characterization of the profile of cancer among vulnerable communities at Sanabel Nour in North Lebanon: an NGO setting P-535 EACR25-1227 Zeina Tarek Dassouki Poster Presenter Lebanon Brain Tumors and Neurodegenerative Diseases: What’s the link? P-536 EACR25-1381 Nicoletta Poler Poster Presenter Italy When clinical meets molecular: CTNNA1 germline alterations are associated with hereditary diffuse gastric cancer development P-537 EACR25-1543 Silvana Lobo Poster Presenter Portugal Genetic Insights into Familial Non-Medullary Thyroid Cancer: Whole Exome Sequencing Reveals Potential Susceptibility Genes in a Representative Family P-538 EACR25-1665 Nicole Viveiros Poster Presenter Portugal Incidence of chronic medical conditions in adolescent and young adult survivors of hematologic malignancies in California, 2006–2020 P-539 EACR25-1701 Renata Abrahao Poster Presenter United States Uncovering Missing Heritability in Prostate Cancer: A Functional Genomics Approach Using Allele-Specific Expression P-540 EACR25-1883 Andr Poster Presenter Portugal Transcriptome-wide Mendelian randomisation exploring dynamic CD4+ T cell gene expression in colorectal cancer development P-541 EACR25-2235 Benedita Deslandes Poster Presenter United Kingdom Subtyping Xeroderma Pigmentosum in Tanzania through blood whole-exome sequencing P-542 EACR25-2243 Mathieu Parmentier Poster Presenter Belgium Poster and Exhibition Hall
10:45 20:00	PREVENTION AND EARLY DETECTION A 8-miRNA risk score-based prediction model for liver cancer rupture P-543 EACR25-0059 Yan Xu Poster Presenter China Helicobacter pylori screening integrated to occupational health surveillance - the HPOS Study P-544 EACR25-0067 Rick Kye Gan Poster Presenter Spain Assessment of a Fiber-rich Diet in Post-treatment Breast Cancer Survivors P-546 EACR25-0311 Mariah Kay Jackson Poster Presenter United States Effects of Immediate Breast Reconstruction on Psychosocial and Sexual Well-Being in Women with Breast Cancer: The Mediating Role of Breast Satisfaction P-547 EACR25-1559 PALOMA GIL-OLARTE Poster Presenter Spain Dietary differences exist among rural and urban cancer survivors P-548 EACR25-1705 Mariah Kay Jackson Poster Presenter United States Intestinal plasma cell senescence as a biomarker for risk prediction of early-onset colorectal carcinogenesis P-549 EACR25-1747 Laissa Almeida Poster Presenter Germany Association between area-based socioeconomic status and colorectal cancer mortality in England P-550 EACR25-2167 Anjum Memon Poster Presenter United Kingdom The role of diet and dietary patterns on colorectal cancer risk, progression and outcomes P-551 EACR25-2393 Mariana Melo Moreira Poster Presenter Portugal The Impact of Prevention in Hereditary Diffuse Gastric Cancer: Clinical and Economic Insights from the EU PREVENTABLE Project EACR25-2313 EACR25-2313 Poster and Exhibition Hall
10:45 20:00	RADIOBIOLOGY / RADIATION ONCOLOGY Dissecting ovarian cancer cellular responses to radioimmunotherapy with β- particle and ultra-short range conversion and Auger electron-emitting radionuclides. P-552 EACR25-0133 Michal Grzmil Poster Presenter Switzerland Experimental alpha-radioimmunotherapy for tumors that have acquired resistance to antibody therapy P-553 EACR25-0197 Sumitaka Hasegawa Poster Presenter Japan Personalized Tumor Models for Precision RadioTheranostics of Glioblastoma P-554 EACR25-0357 Filipa Mendes Poster Presenter Portugal Radiobiology of Image-Guided Radiotherapy: in vitro Impact of Computed Tomography on the Radiosensitivity of Lung Cancer P-555 EACR25-0369 Rana El-Hassan Poster Presenter Lebanon Friedreich’s Ataxia and DNA repair: frataxin deficiency can impair DNA damage mechanisms EACR25-0445 EACR25-0445 Rafka Salim Challita Poster Presenter Lebanon Tumour Volume Dynamics of Glioblastoma During Radiotherapy on 1.5T Magnetic Resonance Imaging-Linear Accelerator P-556 EACR25-0717 Sweet Ping Ng Poster Presenter Australia Ephrin B3 as a Therapeutic Target and Radiosensitizer in Glioblastoma: New Insights P-557 EACR25-0757 Tina Kolenc Milavec Poster Presenter Slovenia Targeting immune signaling to overcome radioresistance by increasing DNA damage in breast cancer cells P-558 EACR25-0957 Sandra Classen Poster Presenter Germany Evaluation of Therapeutic Efficacy of Magnolol Combined with Radiation in Non-small Cell Lung Cancer P-559 EACR25-1059 DE-ZHEN WANG Poster Presenter Taiwan Measurement of radiosensitivity in cervical cancer patients, optimalisation of the RILA method P-560 EACR25-1233 Gy Poster Presenter Hungary Unsupervised Clustering of Histopathological Images: A Promising Tool for AI-based Profiling of Head and Neck Cancer Xenograft Models P-561 EACR25-1271 Cylia Ouadah Poster Presenter Germany ENHANCING CANCER RADIOTHERAPY EFFICACY USING NanOx, A NOVEL OXYGENATING NANOEMULSION THAT REVERSES TUMOUR HYPOXIA. P-562 EACR25-1683 Maiti Poster Presenter Ireland Hypoxic tumor cells acquire a cellular quiescence phenotype that protects them against radiation-induced cell death P-563 EACR25-1929 Apostolos Menegakis Poster Presenter Netherlands Targeting Protein Disulfide Isomerases for Radiation Sensitization in Prostate Cancer P-564 EACR25-2337 Otilia Nuta Poster Presenter Kazakhstan 111In-Radioconjugates Carrying DNA Intercalators and PSMA Inhibitors for Improved Auger Electron Therapy of Prostate Cancer P-565 EACR25-2419 Paula Dolores Raposinho Poster Presenter Portugal EXPLOITING REPLICATION STRESS AS A NOVEL THERAPEUTIC TARGET IN CIC REARRANGED SARCOMAS. P-566 EACR25-2473 waisse WAISSI Poster Presenter France Therapeutic antitumor potential of brachytherapy combined with TLR7 agonist imiquimod P-567 EACR25-2519 Ryszard Smolarczyk Poster Presenter Poland Poster and Exhibition Hall
10:45 20:00	SIGNALING PATHWAYS SoxC transcription factors are oncoembryonic regulators of colon development and cancer P-568 EACR25-0097 Tosca Dalessi Poster Presenter Switzerland Structural characterization of ligand binding to stabilin-2, the Hyaluronic Acid Receptor for Endocytosis (Stab2/HARE). P-569 EACR25-0135 Aleksandra Twarda-Clapa Poster Presenter Poland Receptor-like Tyrosine Kinase as a Promising Therapeutic Target in Pancreatic Cancer: Counteracting Wnt/β-catenin and Sonic Hedgehog/GLI1 Signaling P-570 EACR25-0339 Jung-Ae Kim Poster Presenter Korea (Republic of) Self-antigen presentation drives T-cell leukemia development in a TCR transgenic mouse model P-571 EACR25-0405 Marina Catunda Baessa Poster Presenter Portugal Novel interactions of Mixed-Lineage Kinase 4: identifying key binding partners in breast cancer P-572 EACR25-0443 Vi Truong Poster Presenter Poland H19 Non-Coding RNA expression in Bladder Cancer Tissue as a marker of progression and therapy resistance P-573 EACR25-0621 Edyta Marta Borkowska Poster Presenter Poland APRIL-induced feedback loop regulating BCMA expression in Multiple Myeloma P-574 EACR25-0665 Melanie Faber Poster Presenter Germany The Serine/Threonine phosphatase POPX2 and its effects on cell mechano-sensing P-575 EACR25-0963 Theng Xuan Chua Poster Presenter Singapore Characterizing the Transition from Well-Differentiated to Anaplastic Thyroid Cancer Using Digital Spatial Profiling P-576 EACR25-0973 Gloria Manzotti Poster Presenter Italy Histone deacetylase inhibitors (HDACi) downregulate HER2 protein expression in gastric cancer, leading to pronounced HDACi sensitivity in tumor cells with high basal HER2 expression P-577 EACR25-1023 Achim Aigner Poster Presenter Germany Protective Role of Thymosin Beta 4 Against Sarcopenia via Regulation of PI3K/Akt/mTOR and NLRP3 Signaling Pathways in C2C12 Myotubes P-578 EACR25-1199 Choi Jihye Poster Presenter Korea (Republic of) Generation of an In Vitro Model for the Study of the Aryl Hydrocarbon Receptor Pathway in Adrenocortical Carcinoma Cell P-579 EACR25-1289 Aurora Schiavon Poster Presenter Italy FOSL1 controls chromosomal instability in non-small cell lung cancer (NSCLC) via the β-catenin/TCF4 complex P-580 EACR25-1393 Fabiola Pedrini Poster Presenter Germany Wound Healing Analogy in Medulloblastoma Response to Gap Junction Inhibition and Cytotoxic Therapy P-581 EACR25-1651 Anna-Laura Potthoff Poster Presenter Germany The Alcatraz-Strategy: a roadmap to break the connectivity barrier in malignant brain tumours P-582 EACR25-1659 Anna-Laura Potthoff Poster Presenter Germany The extracellular matrix produced by VEGFR2R1032Q altered melanoma cells modifies adhesive and migratory characteristics of endothelial cells P-583 EACR25-1685 Mattia Domenichini Poster Presenter Italy Downregulation of Frizzled-5 in Gastric Cancer: Tumor Suppressor Potential and the Role of Fibroblast-Derived WNT5A P-584 EACR25-1763 Sarah Zimmer Poster Presenter Germany The Impact of IK Deficiency on Cancer-Related Signaling Pathways: Insights from Zebrafish and Cellular Models P-585 EACR25-1775 Jee Hee Jang Poster Presenter Korea (Republic of) The Androgen Receptor-Serum Response Factor Network As a Pharmacological Target in Castration Resistant Prostate Cancer. P-586 EACR25-1825 Kim Zitzmann Poster Presenter Ireland 11q Loss Meets 17q Gain: Molecular Insights into Neuroblastoma Treatment Resistance P-587 EACR25-2097 Steffanni Sayala Andrade Marques Poster Presenter Brazil Tissue factor augments TGFβ signaling in cancer cells by modulating receptors dynamics and plasma membrane tension. P-588 EACR25-2181 Alessandra Metelli Poster Presenter Italy The effects of progesterone on the expression and functionality of large-conductance voltage- and Ca2+-activated potassium channels in human glioblastoma cells P-589 EACR25-2185 Weronika Piecha Poster Presenter Poland SUPT5H influences Cell Identity in Pancreatic Ductal Adenocarcinoma P-590 EACR25-2315 Marianna Yeza Dittrich Poster Presenter Germany Differential gene expression in immune and metabolic pathways in right and left normal colonic mucosa from Lynch syndrome carriers. P-591 EACR25-2379 F Poster Presenter Spain Distinct Transcriptomic Profiles in Brain Metastases from Lung and Breast Cancer Identify Potential Drug Repurposing Strategies. P-902 EACR25-2513 Iael Weissberg Minutentag Poster Presenter Brazil Novel insights into CDH1 non-coding regulatory elements: effects on E-Cadherin expression, metastasis, and patient outcomes P-592 EACR25-2551 Rita Barbosa-Matos Poster Presenter Portugal Poster and Exhibition Hall
10:45 20:00	TRANSLATIONAL RESEARCH Superclustering-induced activation of death receptors using nanopatterned TRAIL-decorated DNA origami nanostructures P-593 EACR25-0015 Goktug Aba Poster Presenter Netherlands CT Scan Identified Sarcopenia and MST and AND/ASPEN Malnutrition Guidelines in Gastrointestinal Cancer Patients P-594 EACR25-0165 Mariah Kay Jackson Poster Presenter United States Cardiac Remodelling and Incident Cardiovascular Risk in Haematological Cancer Survivors from the UK Biobank P-595 EACR25-0423 Gracia Andriamiadana Poster Presenter United Kingdom Genomic Profiling of Colloid Carcinoma of the Pancreas P-596 EACR25-0479 Michele Bevere Poster Presenter Italy Harnessing Patient-Derived Organoids to Personalise Chemotherapy for Advanced Gastric Cancer P-597 EACR25-0565 Francisco Hettige Tharindie Natashiya Silva Poster Presenter Australia Targeting PI3K-Akt Signalling Pathway in the Search for Novel Therapeutic Strategies for Treatment Resistant High-Grade Serous Ovarian Cancer P-598 EACR25-0585 Anna R Poster Presenter Denmark Evaluation of the Therapeutic Efficacy and Immunomodulatory Effects of Iron Oxide-Conjugated Photosensitizer Nanoparticles in Glioblastoma. P-599 EACR25-0933 Dai-Cheng Dong Poster Presenter Taiwan Incomplete ovarian function suppression (OFS) in premenopausal patients with oestrogen receptor positive breast cancer receiving GnRH agonists/antagonists whilst being treated with CDK4/6 inhibitors P-601 EACR25-1087 Ansaam El-Sherif Poster Presenter United Kingdom BR55: Clinical Development of the First Ultrasound Molecular Imaging Agent for angiogenesis P-602 EACR25-1101 Victor Jeannot Poster Presenter France Melting the Iceberg: Nanomedicines Overcoming Stromal Barriers and Recruiting Effector T Cells in Pancreatic Cancer P-603 EACR25-1133 Rita Ac Poster Presenter Portugal Tiny Warriors Against Tumors: A Nanovaccine Approach for Melanoma Brain Metastases P-604 EACR25-1147 Ana Barbara Carreira Poster Presenter Portugal Results of a Neuroscience Education Program in Adults with Cancer Pain: A Controlled Clinical Trial P-605 EACR25-1187 Leidy Tatiana Ordo Poster Presenter Colombia Establishment and Characterization of a Diabetic Sarcopenia Model in Aged Mice: Insights into Metabolic and Muscular Dysfunction P-606 EACR25-1207 Choi Jihye Poster Presenter Korea (Republic of) Engineering M13 Bacteriophages for Targeted Sonodynamic Therapy of Cancer P-607 EACR25-1223 Michela Nigro Poster Presenter Italy The Impact of Nanoparticle Size on the Enhanced Permeability-Retention Effect in Breast Cancer P-608 EACR25-1259 Baiba Svalbe Poster Presenter Latvia Positioning of MS-AP-030 as a clinical candidate in an adjuvant setting to delay metastasis in colorectal cancer P-609 EACR25-1305 Debabani Roy chowdhury Poster Presenter India Challenges in the Collection of Biological Samples from the Operating Room - The Champalimaud Foundation Biobank Experience P-610 EACR25-1501 Hasti Ant Poster Presenter Portugal Deciphering intestinal zonation and its role in tumour initiation, evolution and progression in mouse models of colorectal cancer P-611 EACR25-1527 Raheleh Amirkhah Poster Presenter United Kingdom Equitable access to Oncology clinical trials in Europe P-612 EACR25-1765 Loic Verlingue Poster Presenter France Rapid laser-based prototyping of microfluidics chips for drug testing on cell cultures P-612A EACR25-1871 Piotr Paweł Bartosz Poster Presenter Poland Enhanced Spatial Proteomics: High-Precision Analysis of the Tumor Microenvironment P-613 EACR25-1927 Jonah Rauer Poster Presenter Germany Patient-derived HER2-positive gastric cancer organoids display differential response to targeted therapies correlating with patients’ outcomes and serving as models to unravel treatment resistance mechanisms P-614 EACR25-1973 Alba Aguilar-Cifre Poster Presenter Spain Enhanced photobleaching for fast and highly multiplexed immunofluorescence staining with broad reagent and assay compatibility P-615 EACR25-1997 Thore B Poster Presenter Germany Intraductal Carcinoma of the Prostate- A Precursor Lesion? P-616 EACR25-2271 Hridya Harikumar Poster Presenter Netherlands A controllable and integrated pump system for high-precision microfluidics used for drug testing and cell cultures P-617 EACR25-2367 Maria Ochman Poster Presenter Poland A Multiomic and Highly Multiplex Method of Imaging Metabolites, Targeted Proteins and Targeted Transcripts on the Same Lung Cancer Tissue Microarray Using Novel Mass-Tagged Affinity Probes P-618 EACR25-2395 Leonardo Garcia Dettori Poster Presenter United States 3D Tumor Spheroids for Assessing Carbon Nanocapsule-Based Neutron Capture Therapy P-619 EACR25-2411 Mafalda Laranjo Poster Presenter Portugal Imaging Mass Cytometry Detects the True Dynamic Range of Low-Abundance Biomarker Expression in Human Tumors P-620 EACR25-2567 Melissa Klug Poster Presenter Expression of SLC27A5, a long chain fatty acid membrane transporter, in clinical breast cancer and the clinical value in assessing the outcome and metastasis EACR25-0079 EACR25-0079 Zhonghang Xu Poster Presenter United Kingdom Poster and Exhibition Hall
10:45 20:00	TUMOUR BIOLOGY Analysis of Perigallbladder Lymphatic Flow as a Pathway of Gallbladder Cancer Progression P-621 EACR25-0061 Atsushi Yamamoto Poster Presenter ACSL3-Mediated MUFA Activation Protects Dormant Breast Cancer Cells from Ferroptosis via Fatty Acid Metabolic Reprogramming P-622 EACR25-0143 Laura Vera-Ramirez Poster Presenter Spain Hypoxia tolerance mechanisms in Head and Neck Squamous Cell Carcinoma P-623 EACR25-0169 Celia Gonzalez Maroto Poster Presenter United Kingdom Modelling the extracellular matrix to elucidate collagen-mediated alterations in colorectal cancer using 3D patient-derived organoids P-624 EACR25-0201 Samna Sagadevan Poster Presenter United Kingdom Genome-Wide Analysis of Intronic Sequence RNAs associated with Invasive Lobular Breast Cancer P-625 EACR25-0207 Emine Beyza Dogan Poster Presenter Turkey the MYC dependent lncRNA MB3 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway P-626 EACR25-0211 alessia grandioso Poster Presenter Italy Characterization Of m6A Regulatory Proteins and Identification Of Target Genes In Invasive Lobular Breast Cancer P-627 EACR25-0213 Yasemin GAZALO_LU Poster Presenter Turkey Investigation of m1A and m6A Methylations in Metastatic and Non-Metastatic Triple-Negative Breast Cancer Cells P-628 EACR25-0217 Buket Sa_lam Poster Presenter Turkey Genome-wide profiling of intronic RNAs in triple-negative ductal breast carcinoma P-629 EACR25-0225 _irin Elife Ceren Poster Presenter Turkey GTF2A1-AS lncRNA orchestrates cisplatin-induced cell death transitions as a stress response regulator P-630 EACR25-0227 Ipek Erdogan-Vatansever Poster Presenter Turkey Identification of Intronic RNAs Involved in Apoptosis P-631 EACR25-0231 Zeynep Buse Orhan Poster Presenter Turkey Dose-Dependent Regulatory Effects of Melatonin on miRNA Expression in PANC-1 Pancreatic Cancer Cells P-632 EACR25-0265 Duygu Sari Ak Poster Presenter Turkey Combined therapy targeting AR and EZH2 restrains the growth of castration resistant prostate cancer by enhancing antitumor T cell response P-634 EACR25-0331 Elena Jachetti Poster Presenter Italy A multitarget drug as potential candidate for antimetastatic adjuvant therapy P-635 EACR25-0333 Juliana Maria Motta Poster Presenter Brazil A whole-genome RNAi screen to identify genes required in Flower-mediated cell competition in Drosophila melanogaster P-636 EACR25-0355 Catarina Mar Poster Presenter Portugal Dichloroacetate modulates tumor cell immunometabolism and inflammation by regulating TNF alpha and nitric oxide in a 4NQO- induced oral carcinoma mouse model P-637 EACR25-0359 Mounia Benbelkacem Poster Presenter Algeria Complement protein C3 from breast cancer-associated fibroblasts as a regulator of the tumor microenvironment P-638 EACR25-0381 Eleni Mourati Poster Presenter Sweden Exploring the role of innervation in thyroid cancer and modulation by therapy-induced senescence P-639 EACR25-0401 Eleonora Muraro Poster Presenter Italy Developmental mosaicism underlying EGFR-mutant lung cancer with multiple primary tumors P-640 EACR25-0409 Ignaty Leshchiner Poster Presenter United States BREAST CANCER CELL-ADIPOSE TISSUE INTERACTION IS REGULATED BY RET/PDGF-B AXIS TO COMMIT IMMATURE ADIPOCYTES IN FAVOR OF TUMOR GROWTH. P-641 EACR25-0425 Sabrina Vallone Poster Presenter Argentina RBP and alternative transcriptome characterization in adenoma-to-colorectal cancer progression P-642 EACR25-0495 Lorenzo Franchitti Poster Presenter Italy A Novel Strategy to Target Pancreatic Ductal Adenocarcinoma Associated Oncogenic circRNAs P-643 EACR25-0501 Dr. Asfar Azmi Poster Presenter Characterization of colon cancer metastases ecosystem by single nuclei RNA sequencing identifies a fibroblast subset as a biomarker for early relapse and as a potential therapeutic target P-644 EACR25-0545 Ma Poster Presenter France Exploring glioblastoma and natural killer cell interactions in a fluidic microphysiological system P-645 EACR25-0557 Pia _i_ek Poster Presenter Slovenia RECQL4 Modulates MHC Class II Expression and Drives an Immune-Evasive Phenotype Associated with Resistance to Immune Checkpoint Therapy in Malignant Melanoma P-646 EACR25-0573 Iris Iris Helfrich Poster Presenter Germany Insights into tumor-host interactions in high-grade serous ovarian cancer using a 3D model of the tumor ecosystem P-647 EACR25-0635 Mar Poster Presenter Finland In vitro models to mimic tumor endothelial cell-mediated immune cell reprograming in lung adenocarcinoma P-648 EACR25-0663 Emilie Navarro Poster Presenter France Engineered 3D Tumor Niches to Study the Impact of Stromal Spatial Heterogeneity on Chemoresistance in Pancreatic Cancer P-649 EACR25-0679 Aleksandra Fomina Poster Presenter Canada Characterization of the tumor microenvironment in pulmonary adenocarcinoma: a new insight into the biology of Spread Through the Alveolar Space P-650 EACR25-0681 Arnaud Driussi Poster Presenter Canada Enhancer RNA highly expressed in human skeletal muscle regulates glioblastoma cell resistance to temozolomide P-900 EACR25-0695 Ekaterina Mikhailovna Stasevich Poster Presenter Russia Deciphering the role of SYNCRIP protein in modulation of drug sensitivity of persistent cancer cells P-651 EACR25-0705 Olga Ivanova Poster Presenter Russia BRCA1 mutations in high-grade serous ovarian cancer affect stromal phenotypes in the tumor microenvironment P-652 EACR25-0733 Hagar Lavon Poster Presenter Israel FMRP Upregulation in Cancer: Implicating FMRP-expressing Cancer-Associated Fibroblasts in Immune Evasion P-653 EACR25-0763 Simge Yucel Poster Presenter Switzerland Analysis of cellular plasticity of DTPs induced by chemotherapy in triple negative breast cancer. P-654 EACR25-0769 Ana Poster Presenter France Mimicking liver inflammation to identify essential genes in hepatocellular carcinoma: Towards a CRISPR screen based on IL-6/STAT3 signaling P-655 EACR25-0775 Alina Krumme Poster Presenter Germany The role of prematurely drug-induced senescent peritoneal cell exosomes in the awakening and progression of dormant ovarian cancer cells P-656 EACR25-0783 Szymon Rutecki Poster Presenter Poland Identifying transcript variants associated with colon cancer: a comparative analysis of 3D spheroid cultures and patient-derived tissues P-657 EACR25-0813 Jovana Despotovi_ Poster Presenter Serbia The CMS4 marker HTR2B serotonin receptor is critical in colorectal cancer cell invasion P-658 EACR25-0837 Idan Carmi Poster Presenter Hungary Human immune cell composition of TME depends on tumor cell line-derived xenograft subtype and tumor burden in genO-BRGSF-HIS mice P-659 EACR25-0841 Fabiane Sonego Poster Presenter France Genetic Ancestry Influence on the Tumor Microenvironment of Colombian Patients with Triple-Negative Breast Cancer P-660 EACR25-0857 YINA TATIANA ZAMBRANO ORDONEZ Poster Presenter Colombia Therapeutic Regimen on A Novel Syngeneic and Cisplatin-resistant HNSCC Cachexia Model P-661 EACR25-0861 Yu-Ning Fann Poster Presenter Taiwan Proteomic Landscapes of Ewing Sarcoma Unravel Immune Regulation of Tumor Progression and Ferroptosis Inhibition Driving Chemotherapy Resistance P-662 EACR25-0911 Sagi Gordon Poster Presenter Israel Differential Scanning Fluorimetry and compound screening enabled the identification of novel series of microRNA-21 targeting compounds P-663 EACR25-0917 DANIELE CARETTONI Poster Presenter Italy Investigate the Anticancer Immunomodulation Mechanism of Fluoxetine Treatment in Oral Squamous Cell Carcinoma P-664 EACR25-0953 PEI EN WANG Poster Presenter Taiwan Tissue-Resident Resting Fibroblasts Function as Tumor Suppressors in the Tumor Microenvironment P-665 EACR25-0969 Lee Dakeun Poster Presenter Korea (Republic of) Impact of L-serine on the pro-carcinogenic effects of colibactin-producing Escherichia coli and the microbial community in APCmin/+ mice P-666 EACR25-1003 Amandine Devaux Poster Presenter France New insights into vitamin D receptor signaling in prostate epithelium reveal therapeutic options and biomarkers for cancer progression P-667 EACR25-1019 Kateryna Len-Tayon Poster Presenter France Advancing CRISPR Mouse Models – Investigating Single-Nucleotide Substitutions in Lung Cancer with Cytosine Base Editing P-668 EACR25-1045 Imke Bullwinkel Poster Presenter Germany Complement signaling is a hallmark of inflammatory fibroblasts in chronic diseases and cancer P-633 EACR25-1049 Yeela Scharff Poster Presenter Israel Reconstructing spatiotemporal dynamics of the tumor and micro-environment in a triple-negative breast cancer murine model P-669 EACR25-1063 Kamil Lisek Poster Presenter Germany Development of a Tumor-On-Chip Model to Predict Drug Response in Breast Cancer P-670 EACR25-1103 zehra elif Gunyuz Poster Presenter Turkey Chromosomal instability as a driver of cGAS-STING dysfunction P-671 EACR25-1139 Amy Kate Hall Poster Presenter United Kingdom Targeting RBP-guided Immune Evasion Enhances Immune Checkpoint Therapy in High-grade Serous Ovarian Cancer P-672 EACR25-1155 Nadine Bley Poster Presenter Germany Extracellular Vesicle Subtypes in Mediating Ovarian Cancer Metastasis P-673 EACR25-1177 Jiajie Liu Poster Presenter Hong Kong, China Structural insights into integrin recognition and inhibition of tumor migration and angiogenesis by disintegrins P-908 EACR25-1185 Cheng-Hsiang Chuang Poster Presenter Taiwan Dysregulated m5C RNA Methylation of HDGF Promotes Colorectal Cancer Growth via De Novo Lipogenesis P-674 EACR25-1191 Gyeonghwa Kim Poster Presenter Korea (Republic of) ADAM10 promotes pancreatic cancer progression and modulates the immune microenvironment P-675 EACR25-1197 Sakshi Arora Poster Presenter Australia A Novel Exosome Inhibitor Limits Tumor Growth in Mice with Melanoma (B16F10) Allograft P-676 EACR25-1201 Li Zhanghao Poster Presenter Hong Kong, China Small nucleolar RNA host gene 10 promotes pancreatic ductal adenocarcinoma via regulating EGFR/AKT/ERK1/2/mTOR cascade P-677 EACR25-1213 GOURI PANDYA Poster Presenter India Development of relevant mouse models for the R&D of therapeutics for Pancreatic Ductal AdenoCarcinoma P-678 EACR25-1215 Malina Xiao Poster Presenter France Disruption of the Pentraxin 3/CD44 Interaction can be an Efficient Strategy for Malignant Cancer Therapy P-679 EACR25-1221 Ju-Ming Wang Poster Presenter Taiwan The local microenvironment suppresses the synergy between irradiation and anti-PD1 therapy in breast-to-brain metastasis P-680 EACR25-1249 Paola Guerrero Aruffo Poster Presenter Switzerland The level of genomic instability in progression of malignant brain cancer P-681 EACR25-1267 Nejla Ademovic Poster Presenter Serbia Activity of a platinum(IV)–flurbiprofen conjugate free and immobilized into mesoporous nanostructured silica on colon cancer P-682 EACR25-1291 Teodora Komazec Poster Presenter Serbia Targeting ROCK Pathway in Diffuse Midline Glioma: Implications for Cell Motility and Invasion P-683 EACR25-1295 Sonia Celeiro Poster Presenter Portugal Organotypic slice cultures: An advanced preclinical platform for testing pancreatic cancer therapies P-684 EACR25-1315 Lucia Juh Poster Presenter Slovakia Alveolar macrophages control fibroblast into CAF fate in Non-Small Cell Lung Cancer (NSCLC) P-685 EACR25-1341 Eduardo Garv Poster Presenter Spain Unleashing the Power of miR-221 Inhibition perspectives for treatment of melanoma P-686 EACR25-1379 Giada Juli Poster Presenter Italy Translational 3D human cell models to decipher invasion and immunosuppression in the high-grade glioma tumor microenvironment P-687 EACR25-1399 In Poster Presenter Portugal Exploring the Crosstalk between Chemoresistant TNBC cells and Tumor-Associated Macrophages: Implications for Tumor Progression P-688 EACR25-1455 Alessandra Caliendo Poster Presenter Italy Plant-based diet consumption exacerbates colitis-driven tumorigenesis in adolescent mice P-689 EACR25-1469 Clarissa Am Poster Presenter Germany HFE polymorphism affects cancer progression both in human and mouse models of pancreatic cancer. P-690 EACR25-1483 Paola Cappello Poster Presenter Italy Luminal ER+ breast cancer cells exhibit an enhanced dormant phenotype in softer matrices P-691 EACR25-1493 Unai Heras Poster Presenter Spain Signaling downstream of tumor-stroma interaction regulates mucinous colorectal adenocarcinoma apicobasal polarity P-692 EACR25-1495 Meri Pelkonen Poster Presenter Finland ROLE OF MAMMARY ADIPOSE TISSUE-DERIVED VERSICAN PROTEOGLYCAN IN BREAST CANCER PROGRESSION AND AGGRESSIVENESS P-693 EACR25-1531 Alessia Parascandolo Poster Presenter Italy Modeling extracellular matrix-tumor interactions in desmoplastic small round cell tumor: development of a new organotypic model P-694 EACR25-1539 Anastasiya Voronovska Poster Presenter Portugal Clinical and molecular characterization of colorectal cancer: is the tumor microenvironment reflected on fecal miRNome and microbial profiles? P-695 EACR25-1575 Virginia Alberin Poster Presenter Italy Study of master regulators involved in brain metastasis development in triple-negative breast cancer. P-696 EACR25-1603 Flavie WOESTELAND Poster Presenter France Oncogenic Molecular Features triggered by the Mechanoresponsive Polycystin proteins P-697 EACR25-1619 Antonios Gargalionis Poster Presenter Greece Deciphering lncRNA MTAAT-Mediated PD-L1 Regulation in T-cell Lymphoma: Implications for Immune Checkpoint Therapy P-698 EACR25-1657 Selene Mallia Poster Presenter Italy Cancer Associated Fibroblasts Exert Immunosuppression Through Upregulation of Endoplasmic Reticulum Stress in Pancreatic Cancer. P-699 EACR25-1663 Debora Barbosa Vendramini Costa Poster Presenter United States CPAP promotes immunosuppression in the tumor microenvironment of Hepatocellular Carcinoma P-700 EACR25-1717 Ching-Jung Cheng Poster Presenter Taiwan Unveiling the Influence of Tumor-Derived CCL20 on B Cell-Mediated Immune Responses in Nasopharyngeal Carcinoma P-701 EACR25-1729 Qin Liu Poster Presenter Hong Kong, China Patient-Derived Tumor Tissue Cultures (PDTTCs) to assess immunotherapy responses in Glioblastoma P-702 EACR25-1737 Laura Carrillo-Bosch Poster Presenter Spain CircFIRRE and circPROX1 are highly expressed in primary and metastatic colon cancer cells P-703 EACR25-1787 Teva Phanaksri Poster Presenter Thailand Bioengineering Unitary Lung Tumor-Stroma Organoids in a Biomimetic Human Extracellular Matrix P-704 EACR25-1797 Margarida Henriques Pereira Poster Presenter Portugal Raf Kinase Inhibitor Protein (RKIP) plays a role more than scaffolding protein by modulating cytokines in colorectal Cancer cell lines P-705 EACR25-1809 MD ABU RAYHAN Poster Presenter Korea (Republic of) CRC multi-omics groups reveal distinct tumor microenvironments P-706 EACR25-1855 Barbora Zwinsov Poster Presenter Czech Republic In vivo CRISPR/Cas9 screening identifies key genes driving prostate cancer progression and metastatic tropism P-707 EACR25-1939 In Poster Presenter Spain Lung fibroblasts regulate disseminated tumor cells survival, dormancy and progression to metastasis through FGFR2 pathway P-708 EACR25-1941 Paula Linzoain Poster Presenter Spain Monitoring Lynch syndrome colonic organoid engraftment in mice cecum P-709 EACR25-1969 Mireia Morell Ginesta Poster Presenter Spain P-Selectin as a Key Regulator of Lung Cancer Brain Metastasis: Altering the Immunophenotype of the Tumor Microenvironment P-710 EACR25-1975 Koren Salomon Poster Presenter Israel Exploring tumor-suppressing fibroblast population in ovarian adenocarcinoma P-711 EACR25-1983 Anastasia Nikolaevna Kazakova Poster Presenter Russia Efferocytosis by peritoneal metastasis-associated fibroblasts reprograms the tumour microenvionment to promote cancer progression P-712 EACR25-2019 Chiara Zotter Poster Presenter Austria Intratumoral heterogeneity in microsatellite instability status at single cell resolution P-713 EACR25-2021 Harrison Anthony Poster Presenter Ireland ERBB Signalling contributes to immune evasion in KRAS-driven lung adenocarcinoma P-714 EACR25-2035 Sarah Laing Poster Presenter United Kingdom PRMT7 as key driver of metastatic process in prostate cancer P-715 EACR25-2037 Marina Hermosilla-Trespaderne Poster Presenter Spain CD24-mediated differential platelets-tumor cells binding tunes metastatic progression P-716 EACR25-2075 Cristina Liboni Poster Presenter France Genetically modified M1 macrophages secreting IL-12 as a potential melanoma anticancer therapy P-717 EACR25-2107 Dorota Sprus-Lipka Poster Presenter Poland Cell viscosity influences hematogenous dissemination and metastatic extravasation of tumor cells P-718 EACR25-2113 Jacky GOETZ Poster Presenter France Dissecting KRAS G12C inhibitor resistance at the transcriptomic level P-719 EACR25-2155 Paraskevi Lagkada Poster Presenter Italy miRNA and circRNA signatures in liquid biopsy for lung cancer early screening P-720 EACR25-2165 Rui Manuel Vieira Reis Poster Presenter Portugal Histamine dihydrochloride induces myeloid cell production of the anti-metastatic protein thrombospondin-1 P-721 EACR25-2173 Nuttida Issdisai Poster Presenter Sweden Lysosome Exocytosis Inhibition Impairs Breast Cancer Cell Invasion P-722 EACR25-2177 Ana Rita Rodrigues Poster Presenter Portugal From genotype to phenotype: how IDH1 mutations alter the landscape of intrahepatic cholangiocarcinoma P-723 EACR25-2191 Agnieszka Seretny Poster Presenter Germany A novel signal amplification technique for multiplex immunofluorescence to detect low-expressed biomarkers in the tumor microenvironment P-723A EACR25-2211 Jade Nguyen Poster Presenter Charting the immune landscape and communication axes in metastatic colorectal cancer with spatial transcriptomics P-724 EACR25-2285 Mattia Toninelli Poster Presenter Italy Unveiling the role of Sialyl-Tn in pancreatic cancer progression and therapy P-725 EACR25-2295 In Poster Presenter Portugal Epitranscriptional interplay of FOXA1 and MYC impact prostate cancer progression P-726 EACR25-2317 Mariachiara Grieco Poster Presenter Italy Therapeutic Potential of miR-379 through modulating Breast Cancer Stem Cells via HSPA5-TGFβ Axis P-727 EACR25-2343 Lili Lin Poster Presenter Ireland Microfluidic System for Tumor Microenvironment Investigation P-728 EACR25-2377 Weronika Losa Poster Presenter Poland Doxorubicin-induced Cardiotoxicity represents a Risk Factor for Lung Metastasis in Osteosarcoma P-729 EACR25-2403 Gabriela Sampaio Ribeiro Poster Presenter Portugal Self-assembling peptide hydrogels as animal-free models of the tumour microenvironment P-730 EACR25-2417 John Curd Poster Presenter United Kingdom Pioneering the study of the RNA-binding protein TDP-43 in ER+ Breast Cancer P-731 EACR25-2429 Luisa A Helguero Poster Presenter Portugal 3D Patient-Derived Tumor Microtissues: Next Level In Vitro Model for Scalable and Reliable Preclinical Drug Testing P-732 EACR25-2433 B Poster Presenter Switzerland Spatial mapping of breast cancer highlights discrete tumour microenvironments and differences in spatial tumour architecture between Black British and White British women P-733 EACR25-2449 Jozafina Basem Haj Shomaly Poster Presenter United Kingdom Unveiling the influence of Citrate on Prostate Carcinoma Tropism to Bone by a microfluidic model of bone metastasis P-734 EACR25-2483 Sofia Avnet Poster Presenter Italy Impact of obesity on the interaction between stem cells and cancer cells in ovarian cancer P-735 EACR25-2491 Agata Ma_gorzata Wilk Poster Presenter Poland Investigating the role of cancer associated fibroblast-derived small extracellular vesicles in the formation of a bone pre-metastatic niche P-735A EACR25-2493 Emily Jane Moss Poster Presenter United Kingdom Studying glioblastoma-associated blood vessel changes across tumor progression to improve targeted therapies P-736 EACR25-2505 Myriam Jaraiz-Rodriguez Poster Presenter Spain High-throughput Bioprinting of Physiomimetic Tumor-Stroma Microenvironment 3D Models for Screening Therapeutics P-737 EACR25-2507 V Poster Presenter Portugal Neuroendocrine plasticity diversity in prostate cancer: role of redox state P-738 EACR25-2517 Isabel Quir Poster Presenter Spain Spatial Profiling of Exhausted T cells Using High-Plex Imaging Mass Cytometr P-739 EACR25-2533 Melissa Klug Poster Presenter Cryobioprinted human tumor models for off-the-shelf preclinical drug screening P-740 EACR25-2539 Maria Monteiro Poster Presenter Portugal Tracking neuroblastoma-derived small extracellular vesicles: uptake and functional impact in the tumor microenvironment P-741 EACR25-2543 Alysia Scott Poster Presenter Ireland characterization of murine bone marrow derived macrophages (BMDM) following Interleukin 6 treatment in two mice strains: C57BL/6 and Balb/c. P-742 EACR25-2569 Ewelina Pilny Poster Presenter Poland High-Throughput Biofabrication of Unitary Lung Tumor Organoids in Superhydrophobic Surfaces P-743 EACR25-2571 Francisca Patr Poster Presenter Portugal Poster and Exhibition Hall
10:45 20:00	TUMOUR EVOLUTION AND HETEROGENEITY Hijacking cerebral blood vessels: therapy-induced transcriptomic reprogramming of vessel co-opting glioma cells P-744 EACR25-0147 Nadine Bauer Poster Presenter Germany New simple 3D model to study tumour-adipocyte communication and cancer progression P-745 EACR25-0383 Irene Torrens-Mart Poster Presenter Spain Pan-cancer analysis of successive whole genome duplication in the 100,000 Genomes Project P-746 EACR25-0555 Evie Smyth Poster Presenter United Kingdom Barcoding-Based Approach Reveals Clonal Heterogeneity in Response to Combinatorial Treatment P-747 EACR25-0643 Devi Anggraini Ngandiri Poster Presenter Germany Characterising the immunogenetic heterogeneity in liver cancer to understand the varied responses to immunotherapy, with a focus on multifocal disease. P-748 EACR25-0879 Abigail Connor Poster Presenter United Kingdom Patient-derived tumor xenografts as models of acquired chemoresistance – studying melanoma, renal cell carcinoma and non-small cell lung cancer P-749 EACR25-1033 Mihaly Cserepes Poster Presenter Hungary HPMA-based polymeric conjugate bearing derivative of HIV protease inhibitor lopinavir successfully reverses P-gp mediated multi-drug resistance in vitro and in vivo P-750 EACR25-1093 Daniil Starenko Poster Presenter Czech Republic The nucleolus connects inflammation and tumor cell plasticity in colorectal cancer. P-751 EACR25-1301 joffrey pelletier Poster Presenter Spain Microfluidic Single-Cell Profiling in Prostate Cancer Bone Metastasis Reveals Ultra-Migratory Subpopulations, Tumour-Bone Crosstalk and CTC Heterogeneity. P-751A EACR25-1563 Daniele Cotton Poster Presenter United Kingdom In Vivo, Time-Dependent Metabolic Flux Analysis of Normal and Tumor Tissue Using MasSpec Pen Technology P-752 EACR25-1677 Michael Tuck Poster Presenter United States Characterizing polyp heterogeneity to identify those at higher risk of progressing to colorectal cancer P-753 EACR25-1755 Laia Bassaganyas Poster Presenter France Metabolic and Tumor Heterogeneity-Driven Strategies to Overcome Platinum Resistance in Ovarian Cancer P-754 EACR25-1911 Francesca Ricci Poster Presenter Italy Elucidating the molecular mechanisms of whole genome doubling in PDAC P-755 EACR25-2259 Deelaka Wellappili Poster Presenter Germany Characterization of breast cancer tumoroid subclones by proteomics for personalized medicine P-756 EACR25-2327 Antonella Raffo Romero Poster Presenter France SP2G: A Tool to Unveil Glioblastoma Migratory Diversity P-757 EACR25-2441 Simone Iori Poster Presenter Italy Metabolic dependencies of anaplastic thyroid carcinoma metastatic cells point to an adaptive evolution? P-758 EACR25-2541 vincenzo davide pantina Poster Presenter Italy Poster and Exhibition Hall
10:45 20:00	TUMOUR IMMUNOLOGY TRIB1 leads to M2 skewing of macrophages in LUSC P-759 EACR25-0039 Dingyu - Lu Poster Presenter Germany Intra-tumoral bacteria in high grade serous ovarian carcinoma P-760 EACR25-0071 Oussama Krami Senhaji Poster Presenter Finland Prognostic role of Immunoscore in colon cancer P-761 EACR25-0119 Yanislav Iliev Poster Presenter Bulgaria Glucocorticoids trigger CD8+ T cell-dependent tumour control P-762 EACR25-0131 Charles LH Earnshaw Poster Presenter United Kingdom Interleukin-15 signaling in Immunosurveillance P-763 EACR25-0183 Fjolla Rexhepi Poster Presenter Canada Immunosurveillance shapes the genetic landscape of intestinal tumors in replication error-deficient mice P-764 EACR25-0261 Ana Vilarinho Poster Presenter Portugal Small cell lung cancer evades immune surveillance through an ERBB2-dependent mechanism P-765 EACR25-0277 Lydia Meder Poster Presenter Germany The profile of gut microbiota in carcinogenesis driven by mutant EGFR in non-small cell lung cancer P-766 EACR25-0299 YunJung Choi Poster Presenter Korea (Republic of) PTP1B inhibition in tumour cell-conditioned macrophages promotes breast cancer by modulating tumour-promoting genes. P-767 EACR25-0399 Neve Elisa Read Poster Presenter United Kingdom Starch degrading bacteria and prebiotic diet synergistically promote anti-tumor immune microenvironment and response to Immune Checkpoint Blockade. P-768 EACR25-0441 Michele Ceccarelli Poster Presenter United States Genome-wide CRISPR screens identify N-glycosylation as regulator of T cell:tumor cell interactions P-769 EACR25-0561 Zowi Huinen Poster Presenter Netherlands Bacteroides Ovatus Is Associated with Clinical Response to Cancer Immunotherapy in Renal Cell Carcinoma P-770 EACR25-0571 Tianyi Chen Poster Presenter China Expression analysis and functional characterization of CD25 on conventional dendritic cells in liver cancer P-771 EACR25-0603 Aurora Gazzillo Poster Presenter Italy COX-2/PGE2 Activity in Cancer Cells: A Key Driver of Metastasis via Immune Escape P-773 EACR25-0743 Massimo Russo Poster Presenter United Kingdom Reprogramming and therapeutic relevance of immunosuppressive cells in the process of prostate cancer metastasis. P-774 EACR25-0801 Vict Poster Presenter Spain The role of immune checkpoints interplay in modulating NK cell activity in ovarian cancer environments P-775 EACR25-0829 Anna Maria Paw_owska-_achut Poster Presenter Poland Unveiling the Landscape of Tumor-Associated Myeloid Lectins in Immunosuppressive Breast Cancer P-776 EACR25-0903 Giacomo Domenici Poster Presenter Portugal Sympathetic-β2 adrenergic receptor drives the formation of pro-metastatic niche in liver metastasis P-777 EACR25-0941 JINGYING ZHOU Poster Presenter Hong Kong, China Infiltration of PD1+ T cells after neoadjuvant FOLFIRINOX treatment associates with improved clinical outcomes in pancreatic cancer P-778 EACR25-0977 Ricki T. Krog Poster Presenter Netherlands Reprogramming of Pro-tumoral Monocyte-derived Macrophages: A Novel Strategy Targeting Cathepsin B and Non-Apoptotic Caspases P-779 EACR25-0995 Emeline Kerreneur Poster Presenter France Deciphering the cellular and molecular mechanisms leading to immune exclusion and Tertiary Lymphoid Structure organization in Non-Small Cell Lung Cancer P-780 EACR25-1017 Pierre-Alexis Da Costa Poster Presenter France HDAC6 inhibition alters T cell function and metabolism in non-small cell lung cancer P-781 EACR25-1021 Sze Ying Tan Poster Presenter Ireland Beyond multidrug resistance: the role of ABCC1 in metabolic detoxification and immune modulation P-782 EACR25-1053 Veronica La Banca Poster Presenter Italy Trem2+ Macrophages as a Novel Therapeutic Target for Metastatic Prostate Cancer P-783 EACR25-1061 Jaione Auzmendi Iriarte Poster Presenter Spain Glutamine scarcity modulates innate immunity in lung cancer P-784 EACR25-1217 WEI-JAN WANG Poster Presenter Taiwan Tumor miRNAs in small-extracellular vesicles dampen the CD8+ T cell response against tumor and predict response to immunotherapy in NSCLC. P-785 EACR25-1245 CHANG Manon Poster Presenter France Indisulam evokes T cell dependent cytotoxicity through mis-splicing in neuroblastoma. P-786 EACR25-1337 Nikolaos Zourdoumis Poster Presenter United Kingdom Analysis of the spatial characteristics of the DLBCL tumor microenvironment utilizing the SignalStar® multiplex immunohistochemistry assay P-787 EACR25-1385 Tamires Oliveira Poster Presenter Netherlands TREM1 neutrophils drive multi-organ metastasis P-788 EACR25-1473 MARIOLA MUNARRIZ PANOS Poster Presenter Spain The single cell landscape of intrahepatic NK cells in colorectal cancer metastasis: diversity and candidate therapeutic targets P-789 EACR25-1511 Domenico Supino Poster Presenter Italy Depleting tumour-infiltrating Tregs to enhance the efficacy of KRAS-mutant targeted therapies in lung cancer P-790 EACR25-1513 Andrea de Castro Poster Presenter United Kingdom Exploiting Tumour Ablation to Augment Anti-cancer Immunotherapy in Hepatocellular Carcinoma P-791 EACR25-1637 Tamara Humphries Poster Presenter United Kingdom PARP inhibitors as immune modulators in metastatic ovarian cancer therapy P-792 EACR25-1727 Michal Hensler Poster Presenter Czech Republic A Nanopore Based Approach for Detection of Fusobacterium nucleatum Subspecies in Colorectal Cancer Tissue P-793 EACR25-1759 William Rosenbaum Poster Presenter Sweden Transcripts containing Retrotransposable Elements play a regulatory role in modulating the functions of Tumor Infiltrating Lymphocytes P-794 EACR25-1891 Francesco Panariello Poster Presenter Italy 2-microglobulin interaction with HLA class I influences the antigenic landscape and the presentation of cancer associated peptides P-795 EACR25-1895 Ana Barajas Molina Poster Presenter United Kingdom Deciphering the complex relationship between diet, the gut microbiota and anti-tumour immunity P-796 EACR25-1915 Rebecca Simpson Poster Presenter Australia Harnessing Mitophagy in Tumor-Associated Macrophages to Enhance Anti-Tumor Immunity P-797 EACR25-1953 PU STE LIU Poster Presenter Taiwan Bacterial Colonization in Breast Cancer: Exploring Fusobacterium nucleatum and Hypoxic Niches P-798 EACR25-1977 Caoimbhe Burke Poster Presenter Ireland Profiling the tumor-resident intracellular microbiota in small cell lung cancer and its influence on chemotherapy sensitivity P-799 EACR25-2069 Wengang Zhang Poster Presenter China In vitro investigation of Parvimonas micra’s role in colorectal cancer progression P-800 EACR25-2125 Marina Rubio Garcia Poster Presenter Sweden Impact of the intratumoral bacteria on immunotherapy outcomes in hepatocellular carcinoma P-801 EACR25-2129 Ugne Balaseviciute Poster Presenter Spain Tumour microenvironment and neoantigens to develop targeted immunotherapy for paediatric neuroblastoma patients P-802 EACR25-2137 Andrea Moreno Manuel Poster Presenter Spain Paracrine and Neoplastic Effects of D-2HG P-803 EACR25-2151 Chloe J Slater Poster Presenter United States Glucocorticoid Receptor: An Oncosuppressor ‘Immune-dependent’ in EGFR-driven Lung Adenocarcinoma P-804 EACR25-2187 Sarah Trouvilliez Poster Presenter Austria BAP1 deletion disrupts IFN-γ signaling and sensitizes ASXL1 mutated myeloid leukemia cells to NK cell cytotoxicity P-805 EACR25-2189 Chiara Badami Poster Presenter Sweden Macrophage-Mediated Fibrosis Drives Immunotherapy Resistance in Melanoma P-806 EACR25-2195 Diletta Di Mitri Poster Presenter Italy The ILC compartment in mismatch repair-deficient colorectal cancers is dominated by CD127-negative ILC1-like cells with cytotoxic activity P-807 EACR25-2199 Zheng Li Poster Presenter Netherlands Comprehensive Profiling of Transgenic Mouse Antibody Repertoires with High-Throughput Single Cell BCR and Whole Transcriptome Sequencing P-808 EACR25-2215 Ajay Sapre Poster Presenter United States Immunomodulatory effects of HuR inhibition in EGFR-TKI resistant NSCLC cells P-809 EACR25-2269 Maria Casciello Poster Presenter Italy PRIMARY HUMAN M1 AND M2 MACROPHAGE TO EVALUATE INFLAMMATORY AND PRO-RESOLVING MEDIATORS AND THEIR ROLE IN TUMOR GROWTH P-810 EACR25-2309 Marc DUBOURDEAU Poster Presenter France The role of TRAIL/TRAIL-receptor bidirectional signaling for NK-cell cytotoxicity against neuroblastoma cells P-811 EACR25-2547 Erna Islamagic Poster Presenter Sweden CD4 T cells in mediating direct anti-tumor activity and MHC class II loss in melanoma patients P-812 EACR25-2595 Fang Zhao Poster Presenter Germany Poster and Exhibition Hall
10:45 20:00	LATE ABSTRACTS - Wednesday Unravelling Thermotolerance in Adrenocortical Carcinoma: Implications for Hyperthermia-Based Therapies P-813 EACR25-3001 Sol Poster Presenter Ireland BOADICEA and its Implications for Breast/Ovarian Cancer Risk Prediction and the Role of Genetic Counselling: An Observational study P-814 EACR25-3003 Shahed Mousa Naser Poster Presenter Italy Proteomic and proteogenomic characterization of triple negative breast cancer P-815 EACR25-3005 Henrik Johan Johansson Poster Presenter Sweden hokD-Based Suicide Gene Therapy: A Promising Strategy for Targeting Lung Cancer Heterogeneity P-816 EACR25-3007 Houria Boulaiz Poster Presenter Spain Exosomal Glycans in Breast Cancer: A Sweet Strategy for Immune Evasion? P-817 EACR25-3011 Brenda Raissa Oliveira Poster Presenter Portugal Distinct bladder tumor microbiome profiles between responders and non-responders to intravesical Bacillus Calmette-Guérin therapy in high-risk non-muscle invasive bladder cancer P-818 EACR25-3013 KyungHwan Kim Poster Presenter Korea (Republic of) Hyaluronan is an effective immunological adjuvant for the creation of protein-based vaccines against HER2/neu-expressing breast cancers P-819 EACR25-3021 Debora Carpanese Poster Presenter Italy Exploring the impact of DNase I on the myeloid cells in Colorectal Peritoneal Carcinomatosis P-820 EACR25-3023 Milladur Rahman Poster Presenter Sweden Characterization of apoptosis inducing natural compounds for the treatment of therapy resistant tumors - with focus on CDK inhibitors P-821 EACR25-3025 Karina Stephanie Krings Poster Presenter Germany Development of niosomes to encapsulate therapeutic deep eutectic systems for cancer applications P-822 EACR25-3029 Joana F Poster Presenter Portugal Deciphering the role of tissue innervation in metastatic breast cancer dormancy P-823 EACR25-3035 Andreia Gon Poster Presenter Portugal Effects of an Extremity Exercise Program on Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer Survivors: A Pre-Post Pilot Study P-824 EACR25-3037 Ya-Jung Wang Poster Presenter Taiwan IRE1 activity regulates tumour and microenvironment cell lineage states while stratifying localised and metastatic prostate cancer P-825 EACR25-3039 Dimitrios Doultsinos Poster Presenter United Kingdom Targeting FMRP and Stress Granules to Overcome Kras-Mediated Chemoresistance in Cancer P-826 EACR25-3041 Mike Altounian Poster Presenter Switzerland Integrating Single-Cell Spatial Whole Transcriptome and Histopathology to Uncover Drivers of Tumor Heterogeneity in Lung Adenocarcinoma and Squamous Cell Carcinoma P-827 EACR25-3043 Christoph Koenig Poster Presenter Deciphering and targeting castration-induced plasticity of luminal progenitor like cells in prostate cancer P-828 EACR25-3045 Anne-Sophie Vieira Aleixo Poster Presenter France Chromosome 8q Gains and Prostate Cancer Aggression P-829 EACR25-3047 Lucy Barton Poster Presenter United Kingdom Isolation and Characterisation of Prostate Cancer Extracellular Vesicles P-831 EACR25-3055 Kate Ellen Duffy Poster Presenter Ireland Metabolic Changes in Breast Cancer Cells: The Glycerolipid Signaling and Dynamics in Tamoxifen Resistance P-832 EACR25-3057 Kamila Baslarov Poster Presenter Czech Republic Development of low-toxic targeted therapies for KRAS-mutant tumours: harnessing synergistic effects of fasting-mimicking diet (FMD) and ascorbate P-833 EACR25-3061 Anastasiya Shmahala Poster Presenter Italy Exploring the Synergistic Anti-cancer Potential of Dodonaea viscosa in Breast Cancer Therapy P-834 EACR25-3063 Janke van Eck Poster Presenter South Africa Development of a spontaneous mouse model to study bone metastases and tumor dormancy P-835 EACR25-3065 Alessandro Genna Poster Presenter Israel MET Serine 1016: A New Handle on Chemoresistance and Cancer Metabolism P-836 EACR25-3067 Chiara Pozzato Poster Presenter Switzerland Reactive oxygen species mediate immunogenic cell death induced by high-dose vitamin C P-837 EACR25-3069 Federica Di Nicolantonio Poster Presenter Italy Transcriptomic and Proteomic Analyses of Bone Marrow of Patients with Extramedullary Multiple Myeloma Reveals Key Proteins Associated with Transendothelial Migration P-838 EACR25-3073 Ellen Purcell Poster Presenter Ireland Identifying response factors to PD1-IL2v therapy P-839 EACR25-3077 Amrita Manchala Poster Presenter Switzerland Subtype classifier from Cancer RNA expression data with per-sample confidence estimate P-840 EACR25-3079 Mayukh Mondal Poster Presenter Germany HDAC5-mediated exosomal Maspin and miR-151a-3p as biomarkers for enhancing radiation treatment sensitivity in hepatocellular carcinoma P-841 EACR25-3083 JeongIn Cho Poster Presenter Korea (Republic of) Investigating the role of coxsackie and adenovirus receptor in lung adenocarcinoma P-842 EACR25-3091 Yassmin Elmasry Poster Presenter United Kingdom Epigenetic Regulation by SMYD3 Promotes Cancer Stemness and Metastatic Potential in Breast Cancer P-843 EACR25-3095 Ummu Guven Poster Presenter Italy Engineered signaling reporter immune cell lines for monitoring immune activation and multidirectional interactions among cancer cells, immune cells, and tumor microenvironmental cells P-844 EACR25-3099 Wan Li Low Poster Presenter United Kingdom Validation of HRD Testing Using OncoDEEP in Ovarian Cancer: Insights from a Diagnostic Laboratory Cohort P-845 EACR25-3101 Katya Mokretar Poster Presenter United Kingdom DNA Methylation-Based Deconvolution Sheds Light on Glioblastoma Heterogeneity and Cell-Type Composition Associated with Patient Survival P-847 EACR25-3105 Iris Lavon Poster Presenter Israel Inhibition of IL6 trans-signalling is sufficient to control metastatic burden by reshaping of the tumour immune environment P-848 EACR25-3107 Matthias Ernst Poster Presenter Australia Impaired cAMP/CREB1 signaling drives mitochondrial dysfunction in skeletal muscle during cancer cachexia. P-849 EACR25-3109 Andrea Graziani Poster Presenter Italy A Multi-Center Real-World Retrospective Study on the Survival Impact of First-Line Therapies in Metastatic Clear Cell Renal Cell Carcinoma in Saudi Arabia P-850 EACR25-3111 Taleen Surrati Poster Presenter Saudi Arabia Tumor-secreted MIF causes cancer cachexia via promoting adipose tissue fibrosis and suppressing adipogenesis P-852 EACR25-3117 Li Shijin Poster Presenter China Chemotherapy-induced senescence promotes profibrotic response and epithelial-to-mesenchymal transition via TGF-β-WNT crosstalk P-853 EACR25-3119 Mohamad Rima Poster Presenter Lebanon A clinically translatable approach for assessing durability of response in tumours in vivo P-854 EACR25-3121 Benjamin Phillips Poster Presenter United Kingdom Discovery and characterization of novel intronic RNAs in lung cancer P-855 EACR25-3125 D_LEK CANSU G Poster Presenter Turkey Dominance of digestive tract cancers in the US: a comprehensive analysis of organ-specific cancer incidence (1999-2021) P-856 EACR25-3127 ROSA RAGOZZINO Poster Presenter Italy Transforming Food Waste into Smart Nanoparticles: A Sustainable Approach to Drug Delivery P-857 EACR25-3129 Muhamad Hawari Mansor Poster Presenter United Kingdom Circulating microRNAs as Liquid Biopsy Biomarkers for Pancreatic Ductal Adenocarcinoma: A Comparative Pilot Study P-858 EACR25-3131 Pinar of Uysal-Onganer Poster Presenter United Kingdom Targeting the Root of the Tumor: Regulation of Breast Cancer Stem Cells Using the C-Terminal Domain of PEDF Protein P-859 EACR25-3135 Josefa Antonia Quiroz Troncoso Poster Presenter Sudan Deer velvet antler extract against primary and metastatic colorectal cancer cells P-860 EACR25-3139 Nicol Poster Presenter Spain Cytokine Release Syndrome Following Nivolumab-Based Chemoimmunotherapy in Metastatic Gastric Adenocarcinoma: A Rare Immune-Mediated Toxicity P-861 EACR25-3141 Muhammad Nafiz Awlia Poster Presenter United Kingdom Exploring Zinc Homeostasis in Prostate Cancer: Foundations for Targeted Therapeutics P-862 EACR25-3143 Katelyn O Poster Presenter Ireland Beyond the Eye: A unique case of Choroidal Melanoma with Extra-ocular Extension P-863 EACR25-3145 Muhammad Nafiz Awlia Poster Presenter United Kingdom Oncogenic Impact of Non-Coding Enhancer Mutations in Bladder Cancer P-864 EACR25-3147 Kelly Butler Poster Presenter United States Proteome-wide profiling uncovers an unexpected mechanism of HES1-regulated mitotic catastrophe in high-grade serous ovarian cancer P-865 EACR25-3153 Jie Bao Poster Presenter Finland Barriers encountered by women in biomedical research careers and leadership and how to overcome them: a qualitative descriptive study P-866 EACR25-3157 Adriana Albini Poster Presenter Italy Empowering the identification and validation of drug candidates targeting oncoproteins and E3 ligase functions P-867 EACR25-3163 Alexandra Fritz Poster Presenter Austria DHODH inhibition overcomes macrophage-mediated resistance to cytarabine in acute myeloid leukemia (AML) P-868 EACR25-3169 Chuqi Wang Poster Presenter Singapore Pre-clinical evaluation of the CDK12/13 inhibitor SR-4835 in cisplatin-sensitive and –resistant ovarian cancer P-869 EACR25-3171 Fr Poster Presenter Austria Microbiome characteristics in patients with carcinoid syndrome with different response to pharmacological treatment P-870 EACR25-3173 Anna Skalniak Poster Presenter Poland Simultaneous Genomic and Transcriptomic Profiling of Single-Cell-Derived Breast Cancer Spheroids P-871 EACR25-3175 Nuria Est Poster Presenter Spain Decoding the Tumour Microenvironment in Colorectal Cancer Liver Metastases: Histopathological Growth Patterns Reveal Distinct Inflammatory and Interferon-ɣ Niches P-872 EACR25-3177 Maria Escriva Conde Poster Presenter Sweden Brain Tumour Initiating Cell Fate Control by Mitochondrial YME1L P-873 EACR25-3181 Claudia S Barros Poster Presenter United Kingdom QUANTROseq, a Transcriptomic based Drug Discovery Platform using Time-Resolved Gene Expression Profiling: Identification of Inhibitors and Degraders of Transcription Factors and Cell Signaling Regulators P-874 EACR25-3183 Sarah Rieser Poster Presenter Austria Development of a monoclonal antibody for targeted therapy to TAS1R3 receptor in metastatic NSCLC P-875 EACR25-3185 Soraya Groba de Antas Poster Presenter Spain Pharmacological targeting of pan-IL-1 signaling disrupts cancer-induced systemic immunosuppression and improves therapeutic vaccine response in HPV16-induced cancer P-876 EACR25-3189 Jeremy Guillot Poster Presenter Switzerland Decoding Drug Efficacy in Glioblastoma: Identifying Pan-Effective Therapeutics Against Tumor-Initiating Cells to Counteract Heterogeneity P-877 EACR25-3191 Adriana Marinaro Poster Presenter Italy Targeting vitamin D and retinoic acid receptors in the fight against ovarian cancer P-878 EACR25-3193 Alice Keirle Poster Presenter Austria Crosstalk Between Androgen Receptor and TRPM8: Impact on Breast Cancer Cell Dynamics P-879 EACR25-3195 Marilena Lanzino Poster Presenter Italy Multiplex imaging-based tumor microenvironment profiling for precision stratification of breast cancer patients P-880 EACR25-3197 Mariana Freire Poster Presenter Portugal Proteomic, Phenotypic and Therapeutic Profiling of Colorectal Cancer Cell Lines using a Single Cell-derived Spheroid Model reveals Changes in Energetic Signatures P-881 EACR25-3203 Helene Sophia Radloff Poster Presenter Germany Assembling Mouse Cells into 3D Fluorescent Mammospheres P-882 EACR25-3205 Ana Maria Capela Poster Presenter Portugal A High-Throughput Reporter Platform to Identify Modulators of Colorectal Cancer Stemness P-883 EACR25-3207 Cornelia Redel-Smirnov Poster Presenter Germany Tertiary lymphoid structures in cervical cancer are associated with high densities of Tregs and MDSCs P-884 EACR25-3209 Cecilia Aquino-Perez Poster Presenter Czech Republic Biotinylated Diaryl Isoxazole Derivatives with Enhanced Janus Kinase 1 Inhibitory, Antiproliferative, and Apoptotic Activities P-885 EACR25-3211 Melike Erg Poster Presenter Turkey The Role of the p53 family in Iron Homeostasis P-886 EACR25-3215 Xinbin Chen Poster Presenter United States Poster and Exhibition Hall