EXPERIMENTAL / MOLECULAR THERAPEUTICS, PHARMACOGENOMICS

17/06/2025 10:45 20:00
Poster and Exhibition Hall
Time Session
10:45
20:00
Chromenone Derivatives as Potential CRM1 Inhibitors for Glioblastoma Therapy
P-354
EACR25-0068
Cristiana Mourato Poster Presenter Portugal
IQS080 is a novel cytosolic multitargeted kinase inhibitor that simultaneously targets key kinase families, making it a promising candidate for the treatment of pancreatic cancer
P-355
EACR25-0084
Alberto Villanueva Poster Presenter Spain
Engineering Bacteriophages for Targeted Photodynamic Cancer Therapy
P-356
EACR25-0086
Alena Kaltenbrunner Poster Presenter Italy
The anthelmintic drug rafoxanide promotes oxidative stress and VDAC1 opening, leading to mitochondrial dysfunction in colorectal cancer cells.
P-357
EACR25-0132
Federica Laudisi Poster Presenter Italy
The synergistic effect of sedanolide and 5-fluorouracil on triggering mitochondria-dependent apoptosis in colorectal cancer cells
P-358
EACR25-0194
Chih-Chung Wu Poster Presenter Taiwan
The interplay between melatonin and alpha-synuclein on melanoma biomolecular signatures
P-359
EACR25-0202
Panagiota S. Filippou Poster Presenter Greece
The anti-cancer activity of novel diazo-derived compounds on triple-negative breast cancer
P-360
EACR25-0220
Ayse Busranur Celik Poster Presenter Turkey
Enhanced Efficacy and Targeted Delivery System of a pH-sensitive ARV-825 Nanomedicine for Glioblastoma Treatment
P-361
EACR25-0228
HIroaki Kinoh Poster Presenter Japan
A genetic signature predicts the response of aggressive paragangliomas to dual PI3K and CDK4/6 inhibition.
P-362
EACR25-0326
Bhargavi Karna Poster Presenter Germany
PI3K-dependent GAB1/Erk phosphorylation renders head and neck squamous cell carcinoma sensitive to PI3Kα inhibitors
P-363
EACR25-0410
Ling-hua Meng Poster Presenter China
Oxyresveratrol inhibits the tumorigenesis and metastasis of human HCC cells by targeting the CCDC19/PLK1/CCNB1 pathways
P-364
EACR25-0414
Hui-Ling Chiou Poster Presenter Taiwan
Integrative Pharmacogenomics in RCC Tumoroids Uncovers Biomarker-Driven Combination Therapies
P-365
EACR25-0450
Tianyi Chen Poster Presenter China
Targeted Delivery of Extracellular Vesicles to Metastatic Breast Cancer Cells Using the Tumor-Targeting Peptide p28
P-366
EACR25-0490
Pedro Gon Poster Presenter Portugal
Modulation of GPR55 and PINK1 in Glioblastoma Multiforme Models by Cannabis sativa and Piper nigrum Metabolites
P-367
EACR25-0516
andres david turizo smith Poster Presenter Colombia
Repurposing the antifungal piroctone olamine as a targeted treatment for pancreatic ductal adenocarcinoma
P-368
EACR25-0532
Sharon Prince Poster Presenter South Africa
Discovery of DAC-1522, a novel Trop2-targeting degrader-antibody conjugate for precision oncology
P-369
EACR25-0618
XUAN ZHANG Poster Presenter China
Punicalagin-mediated suppression of oncogenic properties in ovarian epithelial adenocarcinoma cells
P-370
EACR25-0622
Zeeshan Ahmad Bhutta Poster Presenter Korea (Republic of)
Risk and benefit for basket clinical trials in oncology: a systematic review with meta-analysis
P-371
EACR25-0640
Karolina Strzebonska Poster Presenter Poland
Exploring the Cytotoxic Potential of Calcite on MCF-7 Cells: A Promising Approach for Breast Cancer Treatment
P-372
EACR25-0642
Akansha Kothidar Poster Presenter India
Design and synthesis of CDK9/EZH2 dual-target inhibitors to achieve synergistic antitumor effects
P-373
EACR25-0660
Youhong Hu Poster Presenter China
Investigating the Antitumour Potential of Fucoidan with Everolimus: An in vitro and in vivo Study Focusing on ERα/Akt/mTOR Pathway Suppression
P-374
EACR25-0718
Maha Ramadan Amin Abdollah Poster Presenter Egypt
High-Throughput Screening Identifies Novel Small Molecule Inhibitors of ELP3 with Potent Anti-Cancer Activity In Vivo
P-374A
EACR25-0744
DANIELE CARETTONI Poster Presenter Italy
Novel Tamoxifen Derivatives Suppress Breast Cancer Growth and Alter Cancer-Related Gene Expression
P-375
EACR25-0762
Irem Durmaz Sahin Poster Presenter Turkey
A novel ribosome biogenesis inhibitor, PMR-116, displays broad spectrum efficacy in preclinical tumour models
P-376
EACR25-0930
Luc Furic Poster Presenter Australia
Nanobiotechnological engineering of M13 bacteriophage for EGFR-targeted theranostics
P-377
EACR25-1022
Paolo Emidio Costantini Poster Presenter Italy
KA103, a novel targeted toxin for Head and Neck Cancer
P-378
EACR25-1032
Castaneda Zegarra Sergio Miguel Poster Presenter Norway
Evaluation of the antineoplastic effects of imipridone derivatives in prostate cancer: Novel therapeutic opportunities
P-379
EACR25-1052
Fatima Ghamlouche Poster Presenter Lebanon
Incorporation of disulfide bond into interleukin-2 for enhancing stability, solubility and therapeutic efficacy
P-380
EACR25-1056
Woei-Jer Chuang Poster Presenter Taiwan
In vivo delivery of gemcitabine through HPMA copolymer conjugates: slow drug release kinetics is crucial for potent antitumor activity
P-381
EACR25-1060
Marek Kovar Poster Presenter Czech Republic
Zebrafish Avatar-test predicts tumor response to chemotherapy in Breast Cancer: A co-clinical study for personalized medicine
P-382
EACR25-1072
Raquel Valente Mendes Poster Presenter Portugal
Effect of RID-A proteins in cachexia and tumor metabolism
P-383
EACR25-1110
Marta Fornaro Poster Presenter Italy
Targeting BCKDK to Overcome Paclitaxel Resistance in Breast Cancer: A Novel Therapeutic Approach
P-384
EACR25-1112
Gehad Mahmoud Iraqy Mohamed Poster Presenter United Kingdom
Datopotamab deruxtecan plus PARP inhibition is highly synergistic in 2D and 3D ovarian cancer models
P-385
EACR25-1144
Luna Stockmann Poster Presenter Ireland
Targeted Treatment of Solid Tumors with BRAF Fusions
P-386
EACR25-1186
Joseph Samuel Poster Presenter Canada
Long-term organoids derived from head and neck and ovarian cancer patients closely recapitulate tumor of origin and predict clinical outcome
P-387
EACR25-1204
Louis-Bastien Weiswald Poster Presenter France
Assay development for addressing drug resistance mediated by fibroblasts in ER+ breast cancer
P-388
EACR25-1242
Elisabet Rodr Poster Presenter Sweden
Anisomelic Acid Suppresses HPV-Driven Tumor Growth with Potential TEAD2 Targeting: Evidence from a Xenograft Model and Proteomics
P-389
EACR25-1246
Navid Delshad Poster Presenter Finland
PTPN2/PTPN1 inhibition induces tumor eradication in ALK-positive lymphoma by triggering a combination of ALK-induced oncogenic stress and immune responses
P-390
EACR25-1302
Marta Rubin Poster Presenter Italy
The Superior Therapeutic Potential of Curcumin-Loaded Zinc Oxide Nanoparticles Against Bladder Cancer
P-391
EACR25-1318
Zahraa Salhab Poster Presenter Lebanon
Biological Basis for the Development of CPL410005 as an Antibody-Drug Conjugate
P-392
EACR25-1342
Filip Mitu_a Poster Presenter Poland
HSPGs targeting and multimeric cytotoxic conjugates as a novel PDC strategy against pancreatic cancer
P-393
EACR25-1374
Krzysztof Ciura Poster Presenter Poland
Teaching cells the drug uptake – rational modulation of endocytosis for precise delivery of novel HSPGs targeting conjugate into pancreatic cancer cells
P-394
EACR25-1376
Aleksandra Chor__ewska Poster Presenter Poland
Expression analysis of CTLA-4, PD-1, and PD-L1 in non-small cell lung cancer patients receiving immunotherapy
P-395
EACR25-1378
David Bonnel Poster Presenter
Apoptotic Effects of a Flavone Combination on Brain Metastatic Triple-Negative Breast Cancer Cells
P-911
EACR25-1382
María Losada-Echeberría Poster Presenter Spain
Integrating Proximity Ligation Assay for PD1-PDL1 Immunoassay with Multiplex Immunofluorescence Imaging in Urothelial Carcinoma
P-397
EACR25-1400
Tony Ullman Poster Presenter Sweden
Type I and II BIR domains as targets for cancer therapy
P-398
EACR25-1412
Federica Cossu Poster Presenter Italy
Alpha-1 adrenergic antagonists to sensitize neuroblastoma over isotretinoin theraphy
P-399
EACR25-1416
Francesca Broso Poster Presenter Italy
Muscle-invasive bladder cancer organoids as a functional system to address therapy response: Perspective in advancing precision medicine
P-400
EACR25-1434
Haiyan Yue Poster Presenter Switzerland
MESOPOROUS SILICA NANOPARTICLES FOR THE SELECTIVE DELIVERY OF DOXORUBICIN TO FOLATE RECEPTOR-EXPRESSING CANCER CELLS
P-401
EACR25-1450
Catia MORELLI Poster Presenter Italy
Targeting UBE2N with Novel Non-Covalent Inhibitors: A Drug Discovery Approach to Combat PARPi Resistance in Ovarian Cancer
P-402
EACR25-1458
Shafi Ullah Khan Poster Presenter France
Multimodal targeting of Ephrin A2 in solid tumors using bi-cyclic drug conjugates
P-403
EACR25-1466
Laura Diaz Gil Poster Presenter United Kingdom
Tackling Hepatocellular Carcinoma with novel PROTAC Degraders of eIF6
P-404
EACR25-1474
Giorgia Tempra Poster Presenter Italy
A titanocene-derivative complexed with a myristic-like aliphatic chain exhibits antitumor activity in cisplatin-resistant models both in vitro and in vivo
P-405
EACR25-1484
Marta Guadamillas Poster Presenter Spain
EGFR-STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1-positive prostate cancer
P-430
EACR25-1490
Elsa Gomes Paiva Poster Presenter Portugal
Targeting CITK in high-grade brain tumors: a comparison of polypharmacological and specific inhibitors
P-406
EACR25-1518
Alessia Ferraro Poster Presenter Italy
Development of Lipid-Based Gene Delivery Systems for CAR T Cell Therapy
P-407
EACR25-1520
Margarida Guerreiro Poster Presenter Portugal
Oral liquid crystalline dispersion effect in chemotherapy-induced intestinal mucositis
P-408
EACR25-1600
Raquel Silva Ara Poster Presenter Brazil
Microneedle-mediated delivery of Iron Oxide Nanoparticles & Oxaliplatin with immune checkpoint inhibitors for its induction of ferroptosis and immunomodulation in Head and neck squamous cell carcinoma
P-409
EACR25-1702
Debabrata Tripathy Poster Presenter India
Targeting RRM2: A Dual Approach to Apoptosis and Cell Cycle Control in Atypical Teratoid Rhabdoid Tumors
P-410
EACR25-1710
CHE-CHANG CHANG Poster Presenter Taiwan
ALDH1 Isoform Landscape in Breast Cancer: Advancing Precision Therapies with a Potent ALDH1A3-Selective Inhibitor
P-411
EACR25-1764
Andrada Constantinescu Poster Presenter France
AI and physics based methods to design biopharmaceuticals to fight triple-negative breast cancer
P-412
EACR25-1772
Catarina Tavares Cavaleiro Poster Presenter Portugal
GSK-3 and BCL-XL inhibition mitigates the competitive advantage of APC-mutant colorectal cancer cells
P-413
EACR25-1780
Lidia Atencia Taboada Poster Presenter Netherlands
Mechanistic Insights into the Uptake, Trafficking, Drug Release, and Cytotoxic Efficacy of 5-FU/Irinotecan-Loaded core@shell Nanoparticles in Colorectal Cancer
P-414
EACR25-1788
Dolma Choezom Poster Presenter Germany
A novel gene therapy combination targeting non-small cell lung cancer
P-415
EACR25-1814
Nathan Vella Poster Presenter Malta
Organ-on-chip platforms for assessing fasting-driven therapeutic responses in dynamic 3D tumor models
P-416
EACR25-1832
SILVIA SCAGLIONE Poster Presenter
Oncofetal Chondroitin Sulfate represents a Target for Antibody Drug-Conjugate therapy of Acute Myeloid Leukemia
P-417
EACR25-1836
Joana Mujollari Poster Presenter Denmark
Engineering Subtype-Specific Breast Cancer Models: Decellularized ECM-Based Bioinks for Organoid Culture and Precision Oncology
P-418
EACR25-1858
Juan Antonio Marchal Poster Presenter Spain
Targeted drug delivery with erythrocyte-derived nanovesicles in an organ-on-chip tumor model
P-419
EACR25-1860
SILVIA SCAGLIONE Poster Presenter
Extracellular Vesicles Loaded with miRNAs Target LCP-1 to Inhibit Tumor Growth and Metastasis in Triple-Negative Breast Cancer
P-420
EACR25-1954
Marianna Prokopi Poster Presenter Cyprus
Defining Docetaxel’s Antitumor Effects on Calu3 Lung Cancer Cells Using High-Throughput Live-Cell Imaging
P-421
EACR25-1972
Svenja Meiler Poster Presenter
Combination of PARP Inhibitor Olaparib and a Vascular Disrupting Agent Reduces Tumor Growth in a Xenograft Mouse Model of Prostate Cancer
P-422
EACR25-1992
Evangelia Sereti Poster Presenter Sweden
Cellular response triggered by anticancer agent, C-2028 in breast cancer cells with different expression of key receptors under normoxia and hypoxia conditions
P-423
EACR25-2000
Aleksandra Pa_ka Poster Presenter Poland
Polyoxovanadates with Anti-breast Cancer Activity and Ca2+-ATPase Inhibition Potential
P-424
EACR25-2028
Manuel Aureliano Poster Presenter Portugal
Enhancing Therapeutic Efficacy in Patient-Derived Models of Pancreatic Ductal Adenocarcinoma Using Engineered Placental Mesenchymal Stromal Cells
P-425
EACR25-2036
Laura Drndakova Poster Presenter Slovakia
Investigation of Novel Duocarmycin Payloads Antibody-Drug Conjugates (ADCs) targeting HER2 for Therapeutic Intervention
P-426
EACR25-2066
Enric Arasanz Picher Poster Presenter United Kingdom
Triptonide induces pro-apoptotic effects against medulloblastoma subtypes
P-427
EACR25-2084
Marriam Yaqoob Poster Presenter United Kingdom
Doxorubicin and cGAMP-loaded hypoxia-sensitive polymersomes: A strategy for enhanced tumor growth inhibition and reduced systemic toxicity
P-428
EACR25-2098
Ryszard Smolarczyk Poster Presenter Poland
The effects of a dual GIP/GLP-1 receptor agonist, Tirzepatide, on the response of prostate cancer cells to therapy
P-429
EACR25-2140
Haonan Li Poster Presenter United Kingdom
Exploring Polyoxotungstates as Novel Antitumor Agents for Pancreatic Cancer Therapy
P-431
EACR25-2150
Maria Filomena Botelho Poster Presenter Portugal
Investigating the repurposing potential of cardiometabolic and hormonal medications for breast and ovarian cancer treatment using Mendelian randomisation
P-432
EACR25-2164
Tessa Bate Poster Presenter United Kingdom
Overcoming Gemcitabine Chemoresistance in PDAC with Nanoparticle-Delivered Active Phosphorylated Gemcitabine
P-433
EACR25-2172
Nathalia Ferreira Poster Presenter Germany
Combinations of HDAC and KRAS inhibitors in lung cancer
P-434
EACR25-2208
Jingyu Li Poster Presenter Germany
Subcutaneous controlled release of antibodies and antibody-drug-conjugates with zwitterionic chitosan-based hydrogels
P-435
EACR25-2248
Guillaume Jacquot Poster Presenter France
Effect of doxorubicin and quercetin combined treatment on osteosarcoma model systems
P-436
EACR25-2268
Milena Milivojevic Poster Presenter Serbia
Unlocking the Dual Power of miR-302b in BRCA1 Wild-Type Triple-Negative Breast Cancer: PARP Inhibitor Sensitivity Enhancer and Tumor Microenvironment Shaper
P-437
EACR25-2280
Valentina Fogazzi Poster Presenter Italy
Targeted Metabolomics for Early-Onset Colorectal Cancer: Identification of Novel Therapeutic Targets and Biomarker-Driven Treatment Strategies
P-910
EACR25-2338
María Losada-Echeberría Poster Presenter Spain
MASLiN as hydrophobic anticancer drug carrier: in vitro activity and in vivo biodistribution
P-439
EACR25-2358
Juan Antonio Marchal Poster Presenter Spain
Photodynamic therapy with ring-fused chlorins: a vision-preserving approach for retinoblastoma treatment
P-441
EACR25-2362
Mafalda Laranjo Poster Presenter Portugal
Exploring the impact of photodynamic therapy conditioning on endometrial cancer cells
P-442
EACR25-2370
Mafalda Laranjo Poster Presenter Portugal
The m6A RNA modification sustains neuroblastoma tumor aggressiveness
P-443
EACR25-2388
Denise Sighel Poster Presenter Italy
Evaluation of the effect of novel fascin inhibitors in patient-derived colorectal cancer organoids considering molecular and histological characteristics
P-906
EACR25-2400
Marketa Pavlikova Poster Presenter Spain
Cold Atmospheric Plasma as a Potential Strategy to Target the Invasion and Metastasis Hallmark in Breast Cancer
P-444
EACR25-2418
Mafalda Laranjo Poster Presenter Portugal
Harnessing DNA repair to enhance therapy efficacy in myeloid leukemia: The impact of chronotherapy
P-445
EACR25-2428
Joana Jorge Poster Presenter Portugal
Expression profiles of target genes for approved antibody-drug conjugates in the context of high-grade serous carcinoma
P-446
EACR25-2462
Elsi Pauliina P Poster Presenter Finland
Alpha-aminobutyric acid attenuates DEN and diet-induced MASLD/MASH mice model by suppression of oncogenic signalling pathways KRAS, STAT3 via gut microbiome modulation
P-447
EACR25-2568
Felicianna Felicianna Poster Presenter Hong Kong, China
Combined siRNA targeting of oncogenic NRAS and BRAF drivers as a strategy for mole reversal and melanoma prevention
P-447A
EACR25-15870
Phoebe Antonia Jones Poster Presenter United Kingdom