dos Santos DiasMatheus Netherlands Cancer InstituteThe Netherlands

• Reprogramming immunosuppressive tumor-associated macrophages potentiates standard-of-care therapy in melanoma
  TichetMelanie Speaker Switzerland
• Proffered Paper 3: SoxC transcription factors are oncoembryonic regulators of colon development and cancer
  DalessiTosca Presenter Switzerland
• Proffered Paper 4: Erythrocyte-derived sphingosine-1-phosphate promotes tumor cell survival in the circulation
  VuceticAdriana Presenter Germany
• Therapeutic OVERactivation of oncogenic signaling as a cancer treatment strategy
  dos Santos DiasMatheus Speaker The Netherlands

• Attaching to and Crossing Endothelial Barriers
  JacquemetGuillaume Speaker Finland
• Proffered Paper 7: CD24-mediated differential platelets-tumor cells binding tunes metastatic progression
  LiboniCristina Presenter France
• Proffered Paper 8: Microfluidic Single-Cell Profiling in Prostate Cancer Bone Metastasis Reveals Ultra-Migratory Subpopulations, Tumour-Bone Crosstalk and CTC Heterogeneity.
  CottonThomasDaniele Presenter United Kingdom
• Omomyc is a promising anti-MYC therapy for pediatric medulloblastoma
  EscuderoLaura Speaker Canada

• Genomic epidemiology approaches to elucidate the causes of Early onset colorectal cancer globally
  Perdomo VelasquezSandra Speaker France
• Proffered Paper: Geographic and age-related variations in mutational processes in colorectal cancer
  EACR25-1102
  EACR25-1102
  Díaz-GayMarcos Presenter Spain
• More Than Mutations: A Survival Guide for Nascent Tumours
  AlcoleaMaria Pilar Speaker United Kingdom
• Proffered Paper: Fibroblast specific endoglin deletion increases colorectal cancer tumorigenesis in a subset-specific manner
  EACR25-1472
  EACR25-1472
  AbudukelimuSubinuer Presenter Netherlands
• The burgeoning horizon of early-onset GI cancers
  EngCathy Speaker United States

• Quantitative insights into somatic evolutionary dynamics in healthy and pre-malignant blood
  BlundellJamie Speaker United Kingdom
• Proffered Paper: Unveiling the role of migratory dendritic cells in liver cancer
  EACR25-0607
  EACR25-0607
  VolponiCamilla Presenter Italy
• Clonal Hematopoiesis and Cancer
  BernardElsa Speaker France
• Proffered Paper: Bulk and spatial B cell receptor repertoire analysis to characterize antibody maturation in relation to tertiary lymphoid structures and response to immunotherapy
  EACR25-2072
  EACR25-2072
  PupierGuilhem Presenter France
• Panel Discussion

• Harnessing senescence biology for immune oncology (REMOTE Presentation)
  LoweScott Speaker United States
• Proffered Paper: Targeting senescent macrophages inhibits metastatic dissemination in adrenocortical cancer
  EACR25-0260
  EACR25-0260
  ValPierre Presenter France
• Controlling therapy-induced senescence: novel approaches to senolysis
  KovatchevaMarta Speaker Italy
• Proffered Paper: Therapy-Induced Senescence Promotes Immunogenicity in Acute Myeloid Leukemia Blasts through loss of PRC2-Mediated Regulation
  EACR25-0844
  EACR25-0844
  FuscoSimona Presenter Italy
• Plasticity of Leukemic Stem Cells
  TrumppAndreas Speaker Germany

• Extrachromosomal DNA (ecDNA): Cancer’s Dynamic Circular Genome
  MischelPaul Salomon Speaker United States
• Proffered Paper: Heterogeneous oncogene dosage driven by extrachromosomal DNA determines neuroblastoma response to therapy
  EACR25-0364
  EACR25-0364
  MontuoriGiulia Presenter Germany
• Functional Role of Extrachromosomal Circular DNA in Colorectal, Renal and Bladder Cancers
  RegenbergBirgitte Speaker Denmark
• Proffered Paper: Investigating the impact of extrachromosomal DNA amplification on cell fate decisions and therapy resistance
  EACR25-2262
  EACR25-2262
  SchmargonRachel Presenter Germany
• A general strategy to model ecDNA-mediated focal amplifications in cells and in mice
  VenturaAndrea Speaker

• Dissecting ovarian cancer cellular responses to radioimmunotherapy with β- particle and ultra-short range conversion and Auger electron-emitting radionuclides. (EACR25-0133)
  P-552
  EACR25-0133
  GrzmilMichal Presenter Switzerland
• Pan-cancer analysis of successive whole genome duplication in the 100,000 Genomes Project (EACR25-0555)
  P-746
  EACR25-0555
  SmythEvie Presenter Ireland
• COX-2/PGE2 Activity in Cancer Cells: A Key Driver of Metastasis via Immune Escape (EACR25-0743)
  P-773
  EACR25-0743
  RussoMassimo Presenter United Kingdom
• Depleting tumour-infiltrating Tregs to enhance the efficacy of KRAS-mutant targeted therapies in lung cancer (EACR25-1513)
  P-790
  EACR25-1513
  de CastroAndrea Presenter United Kingdom
• Cytotoxic ILC-1 cells determine outcome of PD-(L)1 blockade in microsatellite instable cancers (EACR25-2039)
  P-522
  EACR25-2039
  Van RoyenPaula Presenter Netherlands