Árpád Szöőr University of Debrecen, Faculty of Medicine Hungary

I am working on developing new generational immune and stem cell therapeutics against various types of solid tumors. Previously, I investigated the effectiveness of chimeric antigen receptor (CAR) expressing and/or bispecific T cell activating molecule (BiTE) secreting T, NK and mesenchymal stem cells on different solid tumor and leukemia models. In my current research, I am investigating and optimizing CAR and UniCAR expressing T cells that recognize the HER2 tumor-specific antigen, as well as CAR NK-92 cell lines in solid tumor models. In addition to these, I am investigating the therapeutic efficacy of the autoantigen recognizing domain expressing CAAR T cells in a murine scleroderma model.