BaggioliniArianna Institute of Oncology ResearchSwitzerland

• Welcome Message
  CaffarelMaria M. Chair Spain
• FAK Inhibition Promotes Critical Cytotoxic Interactions Between CD8 T Cells and Cancer Cells in Metastatic Breast Cancer
  BarthNicole Speaker United Kingdom
• Proffered Paper 1: Inhibition of Furin in CAR macrophages directs them toward a proinflammatory phenotype and enhances their antitumor activities
  ZIANE CHAOUCHE Lydia Presenter France
• Proffered Paper 2: Multimodal analysis of spatial transcriptomics data uncovers novel invasive lobular carcinoma subtypes
  SerraMatteo Presenter Belgium
• Targeting cytokine signalling to block cancer-promoting inflammation and tumour progression
  CaffarelMaria M. Speaker Spain

• Exploiting metabolic vulnerabilities to improve breast cancer therapy
  MorandiAndrea Speaker Italy
• Proffered Paper 5: Melting the Iceberg: Nanomedicines Overcoming Stromal Barriers and Recruiting Effector T Cells in Pancreatic Cancer
  AcúrcioCRita Presenter Portugal
• Proffered Paper 6: ENO3PEP vaccine enhances chemotherapy efficacy in pancreatic cancer by boosting anti-tumor immunity
  BrugiapagliaSilvia Presenter Italy
• Stem cells-based models of tumor initiation and metastasis
  BaggioliniArianna Speaker Switzerland
• Refreshment Break

• Identifying and targeting metabolic vulnerabilities in leptomeningeal metastasis
  BoireAdrienne Speaker United States
• Proffered Paper: Reshaping Tumor-Vascular-Immune Crosstalk by VEGFR-3 Modulation in Breast Cancer Brain Metastases
  EACR25-1283
  EACR25-1283
  MacelaCarolina Presenter Portugal
• Strategies to challenge brain metastases in mice and human
  ValienteManuel Speaker Spain
• Proffered Paper: Loss of Kmt2c or Kmt2d drives brain metastasis via KDM6A-dependent upregulation of MMP3
  EACR25-1678
  EACR25-1678
  SeehawerMarco Presenter United States
• Unraveling the Complexity of Cancer Ecosystems
  JoyceJohanna A Speaker Switzerland

• The neural regulation of small cell lung cancer progression
  VenkateshHumsa Speaker United States
• Proffered Paper: Medullary sinus macrophages limit cancer therapy efficacy by an efferocytosis-induced IL-33/ST2 axis in the tumor-draining lymph node.
  EACR25-1319
  EACR25-1319
  LamorteSara Presenter Canada
• Neural mechanisms of brain tumor growth and resistance
  WinklerFrank Speaker Germany
• Proffered Paper: Spatially Resolved Analysis of Cancer-Infiltrated Nerves Identifies DRAXIN as a Marker of Injury Response with Tumor-Suppressive Potential
  EACR25-1355
  EACR25-1355
  OzgaJoannaAleksandra Presenter Switzerland
• Neural-tumour communication accelerates cancer progression and impairs treatment response
  SloanErica Speaker Australia