CaffarelMaria M. Biogipuzkoa Health Research InstituteSpain

Time	Session

14:00 15:40	Cancer Researchers to watch - An early career showcase (Separate pre-registration required) BaggioliniArianna Chair Switzerland Welcome Message CaffarelMaria M. Chair Spain FAK Inhibition Promotes Critical Cytotoxic Interactions Between CD8 T Cells and Cancer Cells in Metastatic Breast Cancer BarthNicole Speaker United Kingdom Proffered Paper 1: Inhibition of Furin in CAR macrophages directs them toward a proinflammatory phenotype and enhances their antitumor activities ZIANE CHAOUCHE Lydia Presenter France Proffered Paper 2: Multimodal analysis of spatial transcriptomics data uncovers novel invasive lobular carcinoma subtypes SerraMatteo Presenter Belgium Targeting cytokine signalling to block cancer-promoting inflammation and tumour progression CaffarelMaria M. Speaker Spain Auditorium VIII

Time

Session

14:00

15:40

Cancer Researchers to watch - An early career showcase

(Separate pre-registration required)

BaggioliniArianna Chair Switzerland

Auditorium VIII

Time	Session

08:30 10:00	Cancer Researchers to watch - An early career showcase (Separate pre-registration required) CaffarelMaria M. Chair Spain Exploiting metabolic vulnerabilities to improve breast cancer therapy MorandiAndrea Speaker Italy Proffered Paper 5: Melting the Iceberg: Nanomedicines Overcoming Stromal Barriers and Recruiting Effector T Cells in Pancreatic Cancer AcúrcioCRita Presenter Portugal Proffered Paper 6: ENO3PEP vaccine enhances chemotherapy efficacy in pancreatic cancer by boosting anti-tumor immunity BrugiapagliaSilvia Presenter Italy Stem cells-based models of tumor initiation and metastasis BaggioliniArianna Speaker Switzerland Refreshment Break Auditorium VIII

Time

Session

08:30

10:00

Cancer Researchers to watch - An early career showcase

(Separate pre-registration required)

CaffarelMaria M. Chair Spain

Auditorium VIII

Time	Session

09:20 10:55	Symposium: New Drugs on the Horizon WestermarckJukka Co-Chair Finland CaffarelMaria M. Co-Chair Spain Drugging transcription factors: HSF1 and Brachyury WorkmanPaul Speaker United Kingdom Proffered Paper: Inhibition of WEE1 kinase activity to overcome secondary resistance to targeted therapies in colorectal cancer EACR25-0376 EACR25-0376 ArenaSabrina Presenter Italy Targeting chromatin proteins for therapeutic benefit in haematological malignancy SomervailleTim Speaker United Kingdom Proffered Paper: Reversing Acidic Immune Suppression in Cancer with PTT-4256, A First-In-Class Small Molecule Inhibitor of GPR65 EACR25-0553 EACR25-0553 CorbinAlastair Presenter United Kingdom PP2A inhibitor protein CIP2A is a prime target for TNBC therapy WestermarckJukka Speaker Finland Auditorium I

Time

Session

09:20

10:55

Symposium: New Drugs on the Horizon

WestermarckJukka Co-Chair Finland

CaffarelMaria M. Co-Chair Spain

Auditorium I