GeorgiosSflomos EPFLSwitzerland

George Sflomos is a Senior Cancer Research Scientist based in Switzerland. His research focuses on Invasive Lobular Carcinoma (ILC), a common yet historically understudied subtype of breast cancer. He has helped advance physiologically relevant preclinical models—including intraductal in vivo approaches—to better capture ILC growth, hormone responsiveness, and metastatic behavior. His work also interrogates tumor–microenvironment interactions, including extracellular matrix remodeling pathways, and has highlighted LOX/LOXL-axis biology (including LOXL1) as a potential therapeutic vulnerability in lobular disease.

Sunday 07 June 2026

Time	Session

14:00 15:40	Cancer Researchers to watch - An early career showcase (Separate pre-registration required) GeorgiosSflomos Chair EPFLSwitzerland Welcome Message GeorgiosSflomos Chair EPFLSwitzerland Therapeutic OVERactivation of oncogenic signaling as a cancer treatment strategy MatheusHenriqueDias Speaker Princess Máxima CenterNetherlands Proffered Paper 1: Lipid-associated macrophages in amoeboid cancer cell dissemination EACR26-1833 EACR26-1833 SamanthaLaurenGeorge Oral Presenter Institute of Cancer ResearchUnited Kingdom Proffered Paper 2: Spatial/single-cell profiling of Tfh niches and CD8 exhaustion in glofitamab resistance EACR26-0682 EACR26-0682 PaulMarcoux Oral Presenter CRCT - INSERMFrance Raising from the ashes of treatment – understanding and targeting persister cells YaaraOren Speaker Tel Aviv UniversityIsrael Room F1+2+3

Time

Session

14:00

15:40

Cancer Researchers to watch - An early career showcase

(Separate pre-registration required)

GeorgiosSflomos Chair EPFLSwitzerland

Welcome Message

GeorgiosSflomos Chair EPFLSwitzerland
Therapeutic OVERactivation of oncogenic signaling as a cancer treatment strategy

MatheusHenriqueDias Speaker Princess Máxima CenterNetherlands
Proffered Paper 1: Lipid-associated macrophages in amoeboid cancer cell dissemination

EACR26-1833

EACR26-1833

SamanthaLaurenGeorge Oral Presenter Institute of Cancer ResearchUnited Kingdom
Proffered Paper 2: Spatial/single-cell profiling of Tfh niches and CD8 exhaustion in glofitamab resistance

EACR26-0682

EACR26-0682

PaulMarcoux Oral Presenter CRCT - INSERMFrance
Raising from the ashes of treatment – understanding and targeting persister cells

YaaraOren Speaker Tel Aviv UniversityIsrael

Room F1+2+3

Monday 08 June 2026

Time	Session

08:30 10:00	Cancer Researchers to watch - An early career showcase (Separate pre-registration required) MircoJ.Friedrich Chair German Cancer Research Center and HI-STEM GmbHGermany Preclinical Modeling of Breast Cancer in Context and the Lobular Paradigm GeorgiosSflomos Speaker EPFLSwitzerland Proffered Paper 6: Stromal β3-integrin signature predicting recurrence in Oncotype DX low-risk breast cancer EACR26-1448 EACR26-1448 AlexJordan Oral Presenter Barts Cancer InstituteUnited Kingdom Proffered Paper 7: Spatial trajectories of TNBC tumorigenesis reveal orchestrated TME niches in time and space EACR26-0433 EACR26-0433 KamilLisek Speaker MDC - BIMSBGermany Targeting the untargetable: KRAS, microenvironment and beyond in Pancreatic Cancer Bristi Basu Speaker University of CambridgeUnited Kingdom Room F1+2+3
12:30 13:45	Networking Event for Early-Career Researchers (open to EACR Early Career & Student Members, pre-registration required) Networking Event - Table hosts AlexandraBoitor Moderator European Association for Cancer ResearchUnited Kingdom AmaiaLujambio Moderator The Mark Foundation for Cancer ResearchUnited States GeorgiosSflomos Moderator EPFLSwitzerland GuillaumeJacquemet Moderator Åbo Akademi UniversityFinland HenriettButz Moderator National Institute of OncologyHungary Maria M.Caffarel Moderator Biogipuzkoa Health Research InstituteSpain MariangelaRusso Moderator University of TorinoItaly MatheusHenriqueDias Moderator Princess Máxima CenterNetherlands MeravCohen Moderator Tel Aviv UniversityIsrael MichaelKilian Moderator Brigham and Women's Hospital and Harvard Medical SchoolUnited States MircoJ.Friedrich Moderator German Cancer Research Center and HI-STEM GmbHGermany Natalie Scholes Moderator Netherlands Cancer Institute (NKI)Netherlands SandraBlanco Benavente Moderator Universidad de SalamancaSpain ShaliniVasudevRao Moderator Cancer Research UK, Cambridge Institute, University of CambridgeUnited Kingdom YaaraOren Moderator Tel Aviv UniversityIsrael Career Development Area

Tuesday 09 June 2026

Time	Session

18:15 18:40	Posters in the Spotlight I - Tuesday Spotlight Theatre GeorgiosSflomos Moderator EPFLSwitzerland Single‑Cell Genomic Profiling of 218 HR+/HER2– Breast Tumours Reveals Extensive Intratumoral Genetic Heterogeneity in Early‑Stage Disease EACR26-1632 EACR26-1632 AndreyYurchenko Poster Spotlight Institut Gustave RoussyFrance Tumour-sensing stroma establish Treg-mediated immune suppression in metastatic ovarian cancer via GITRL-GITR signalling EACR26-0256 EACR26-0256 Julia Moreno-Vicente Poster Spotlight University of Cambridge, Cancer Research UK-Cambridge InstituteUnited Kingdom Multiplexed single-cell drug response profiling (4iDRP) for predictive precision oncology EACR26-0346 EACR26-0346 Arpan KumarRai Poster Spotlight University of ZurichSwitzerland The immunological road to bone: the role of B cells in breast cancer bone metastasis EACR26-1114 EACR26-1114 AnaTeijeiro Poster Spotlight National Institutes of Allergy and Infectious DiseasesUnited States From metastasis suppression to metabolic vulnerability: RKIP rewires mitochondrial metabolism in triple-negative breast cancer EACR26-1612 EACR26-1612 JoanaPinheiro Poster Spotlight Life and Health Sciences Research Institute (ICVS)Portugal Room P1+2+3

Time

Session

18:15

18:40

Posters in the Spotlight I - Tuesday

Spotlight Theatre

GeorgiosSflomos Moderator EPFLSwitzerland

Single‑Cell Genomic Profiling of 218 HR+/HER2– Breast Tumours Reveals Extensive Intratumoral Genetic Heterogeneity in Early‑Stage Disease

EACR26-1632

EACR26-1632

AndreyYurchenko Poster Spotlight Institut Gustave RoussyFrance
Tumour-sensing stroma establish Treg-mediated immune suppression in metastatic ovarian cancer via GITRL-GITR signalling

EACR26-0256

EACR26-0256

Julia Moreno-Vicente Poster Spotlight University of Cambridge, Cancer Research UK-Cambridge InstituteUnited Kingdom
Multiplexed single-cell drug response profiling (4iDRP) for predictive precision oncology

EACR26-0346

EACR26-0346

Arpan KumarRai Poster Spotlight University of ZurichSwitzerland
The immunological road to bone: the role of B cells in breast cancer bone metastasis

EACR26-1114

EACR26-1114

AnaTeijeiro Poster Spotlight National Institutes of Allergy and Infectious DiseasesUnited States
From metastasis suppression to metabolic vulnerability: RKIP rewires mitochondrial metabolism in triple-negative breast cancer

EACR26-1612

EACR26-1612

JoanaPinheiro Poster Spotlight Life and Health Sciences Research Institute (ICVS)Portugal

Room P1+2+3

Wednesday 10 June 2026

Time	Session

09:20 10:55	Symposium: Tumour Innervation AndreasTrumpp Co-Chair HI-STEM GmbH in the German Cancer Research CenterGermany GeorgiosSflomos Co-Chair EPFLSwitzerland Targeting the pro-tumorigenic effects of TGFb in tumor treatment Carl-HenrikHeldin Speaker Uppsala UniversitySweden Proffered Paper: Neural features underlying pancreatic cancer cell responses to nerve-derived signals EACR26-1410 EACR26-1410 Kim HoaHo Oral Presenter German Cancer Research Center DKFZGermany The role of neurons in carcinomas AndreasTrumpp Speaker HI-STEM GmbH in the German Cancer Research CenterGermany Proffered Paper: How Neural Phenotypes Dictate the Synaptogenic Microenvironment and Functional Connectivity in Glioblastoma EACR26-0081 EACR26-0081 LynnMenzl Oral Presenter Universitätsklinikum ErlangenGermany Pulmonary innervation impacts tumour progression: A tale of two cancers LeanneLi Speaker The Francis CRICK InstituteUnited Kingdom Room F6+7+8

Time

Session

09:20

10:55

Symposium: Tumour Innervation

AndreasTrumpp Co-Chair HI-STEM GmbH in the German Cancer Research CenterGermany

GeorgiosSflomos Co-Chair EPFLSwitzerland

Targeting the pro-tumorigenic effects of TGFb in tumor treatment

Carl-HenrikHeldin Speaker Uppsala UniversitySweden
Proffered Paper: Neural features underlying pancreatic cancer cell responses to nerve-derived signals

EACR26-1410

EACR26-1410

Kim HoaHo Oral Presenter German Cancer Research Center DKFZGermany
The role of neurons in carcinomas

AndreasTrumpp Speaker HI-STEM GmbH in the German Cancer Research CenterGermany
Proffered Paper: How Neural Phenotypes Dictate the Synaptogenic Microenvironment and Functional Connectivity in Glioblastoma

EACR26-0081

EACR26-0081

LynnMenzl Oral Presenter Universitätsklinikum ErlangenGermany
Pulmonary innervation impacts tumour progression: A tale of two cancers

LeanneLi Speaker The Francis CRICK InstituteUnited Kingdom

Room F6+7+8