Detailed Programme - 18 June 2025

Time	Session

08:30 09:15	EditCo Bio: Uncovering Novel Cancer Therapeutic Targets: Accelerating Discovery Through Streamlined CRISPR Cell Engineering HardcastleTravis Industry Moderator/ Chair United States Introduction HardcastleTravis Industry Moderator/ Chair United States Unveiling SURF2’sRole in Nucleolar Stress and Its Potential as a Therapeutic Target LebaronSimon Industry Speaker France AI-driven identification and validation of novel synthetic lethal gene pairs MillerDaniel Industry Speaker United Kingdom Leveraging an advanced CRISPR platform to streamline oncology breakthroughs SoenensAmalia Industry Speaker United States Auditorium II		Arima Genomics: Transposable elements reorganise the 3D genome structure in CDK4/6 inhibitors resistant breast cancer Transposable elements reorganise the 3D genome structure in CDK4/6 inhibitors resistant breast cancer. Achinger-KaweckaJoanna Industry Speaker Australia Auditorium VI+VII		Meet the Expert - Interactive Session TrumppAndreas Moderator Germany Advancing Science Through Industry-Academic Collaboration: Pre-Clinical Development of KRAS Modulators HofmannMarco Speaker AustriaYes Tumor Archetypes Reimagined: Multi-Omic Insights, AI-Driven Discovery, and New Frontiers in Cancer Subtyping SinaNassiri Speaker Switzerland Discussion with the Experts Career Discovery Area
09:20 10:55	Symposium: New Drugs on the Horizon WestermarckJukka Co-Chair Finland CaffarelMaria M. Co-Chair Spain Drugging transcription factors: HSF1 and Brachyury WorkmanPaul Speaker United Kingdom Proffered Paper: Inhibition of WEE1 kinase activity to overcome secondary resistance to targeted therapies in colorectal cancer EACR25-0376 EACR25-0376 ArenaSabrina Presenter Italy Targeting chromatin proteins for therapeutic benefit in haematological malignancy SomervailleTim Speaker United Kingdom Proffered Paper: Reversing Acidic Immune Suppression in Cancer with PTT-4256, A First-In-Class Small Molecule Inhibitor of GPR65 EACR25-0553 EACR25-0553 CorbinAlastair Presenter United Kingdom PP2A inhibitor protein CIP2A is a prime target for TNBC therapy WestermarckJukka Speaker Finland Auditorium I		Symposium: Tumour Innervation BaggioliniArianna Co-Chair Switzerland WinklerFrank Co-Chair Germany The neural regulation of small cell lung cancer progression VenkateshHumsa Speaker United States Proffered Paper: Medullary sinus macrophages limit cancer therapy efficacy by an efferocytosis-induced IL-33/ST2 axis in the tumor-draining lymph node. EACR25-1319 EACR25-1319 LamorteSara Presenter Canada Neural mechanisms of brain tumor growth and resistance WinklerFrank Speaker Germany Proffered Paper: Spatially Resolved Analysis of Cancer-Infiltrated Nerves Identifies DRAXIN as a Marker of Injury Response with Tumor-Suppressive Potential EACR25-1355 EACR25-1355 OzgaJoannaAleksandra Presenter Switzerland Neural-tumour communication accelerates cancer progression and impairs treatment response SloanErica Speaker Australia Auditorium II		Symposium: Normal Tissue (not Blood) SalvadorBeatriz Co-Chair United KingdomYes RisquesRosana Co-Chair United States Clonal evolution of cancer from initiation to metastasis in the mouse (REMOTE Presentation) BalmainAllan Speaker United States Proffered Paper: Pancreatic Cancer Initiation: Wnt Signalling and Cell Dormancy Enable Kras Mutant Cell Survival EACR25-0647 EACR25-0647 SalvadorBeatriz Presenter United KingdomYes PEDIA-BRAIN: Building a normal brain tissue development encyclopedia as a comparator for pediatric CNS malignancies MardisElaine R. Speaker United States Proffered Paper: Dietary Histidine controls intestinal stem cell activity, providing a potential protective role against colorectal cancer EACR25-0457 EACR25-0457 BiehlerCornélia Presenter Finland Somatic evolution in normal tissues and cancer risk RisquesRosana Speaker United States Auditorium VI+VII
10:55 11:35	Coffee Break / Exhibition/ Industry Spotlight Poster and Exhibition Hall
11:15 11:30	TECAN Industry Spotlight: Label-free spheroids and organoids analysis for assays development VettoreNicola Industry Speaker Germany Label-free spheroids and organoids analysis for assays development VettoreNicola Industry Speaker Germany Spotlight Theatre
11:35 13:10	Symposium: Cancer Genomics CaldasCarlos Co-Chair Israel Epigenetic dysregulation and cancer evolution ScaffidiPaola Speaker Italy Proffered Paper: Integrative multi-omic approach to identify patterns of immune selection in primary breast tumours EACR25-0508 EACR25-0508 MonterdeBeatriz Presenter United Kingdom EMBO Young Investigator Lecture: Cancer aneuploidy - From evolutionary pressures to cellular vulnerabilities (REMOTE PRESENTATION) Ben-DavidUri Speaker Israel Proffered Paper: Genetic background sets the trajectory of cancer evolution EACR25-2424 EACR25-2424 AitkenJSarah Presenter United StatesYes Title to be announced TurajlicSamra Speaker United Kingdom Auditorium I	Joint EACR - EMBO Symposium: Advanced in vitro Models ChumduriCindrilla Co-Chair Denmark BernardsRene Co-Chair Netherlands Cell plasticity in human colon and cancer SnippertHugo Speaker Netherlands Proffered Paper: Contact-based transfer of thymidylate promotes collective tumor growth EACR25-0343 EACR25-0343 SiddiquiMohammad Aarif Presenter Denmark Development of advanced immunotherapies using human 3D-bioprinted cancer avatars Satchi-FainaroRonit Speaker Israel Proffered Paper: Deconvolution of heterogeneous 3D mammary spheroid dynamics using Oblique Plane Microscopy (OPM) EACR25-2342 EACR25-2342 ModerauNina Presenter United Kingdom Deciphering the role of infection and diet in driving early carcinogenic events using advanced organoid models and omics ChumduriCindrilla Speaker Denmark Auditorium II		Joint EACR - ASPIC Symposium: Cancer Therapy Resistance AmbrogioChiara Co-Chair Italy ParedesJoana Co-Chair Portugal Studying melanoma therapy resistance one cell at the time MarineJean-Christophe Speaker Belgium Proffered Paper: Dynamics and chemotherapy response of single cell-derived human breast cancer clones EACR25-0507 EACR25-0507 KronheimRachaelSarah Presenter Canada The role of RANK signaling in breast cancer biology and response to therapy CasimiroSandra Speaker Portugal Proffered Paper: Unveiling the impact of intratumoral microbiota in the treatment efficacy of soft tissue sarcoma EACR25-0716 EACR25-0716 TiraboschiLuca Presenter Italy Mechanism of response and resistance to RAS inhibition in solid tumors MisaleSandra Speaker United States Auditorium VI+VII		Symposium: Tumour Dormancy BoitorAlexandra Co-Chair United Kingdom CorreiaAna Luisa Co-Chair Portugal Unravelling mechanisms of ER+ Breast cancer dormancy GomisRoger Speaker SpainYes Proffered Paper: Translational Reprogramming Drives Immune Evasion in Melanoma Persister Cells Through MIF Secretion EACR25-2481 EACR25-2481 SoumoyLaura Presenter France What makes a tissue favorable or not to metastasis? CorreiaAna Luisa Speaker Portugal Proffered Paper: Neuroblastoma metastatic cells adopt an embryonic diapause-like state in the fetal bone marrow driven by mTOR activity EACR25-0988 EACR25-0988 Castillo FerrerCamila Presenter France How host niche variations regulate disseminated cancer cell dormancy and awakening Aguirre-GhisoJulio A. Speaker United States Auditorium VIII
13:15 15:15	Lunch Break / Exhibition / Poster Viewing Poster and Exhibition Hall
13:30 14:15	Akoya Biosciences, Inc.: Scaling Immuno-Oncology Research with IO60: The Fastest UltraHigh-Plex Spatial Proteomics Panel Title TBC Ivan Masetto Industry Speaker Title TBC HunterKelly Industry Speaker United Kingdom Titel TBC TissotStéphanie Industry Speaker Switzerland Titel TBC TissotStéphanie Industry Speaker Switzerland Titel TBC TissotStéphanie Industry Speaker Switzerland Auditorium II		Illumina: Unlocking the Power of Single-Cell and Spatial Multiomics for Cancer Research Introducing Illumina Single Cell and Spatial Technology Scalable single-cell RNA profiling of pooled CRISPR screens discloses novel biology of cancer and T cells Van MinselPaulien Industry Speaker Belgium Cell Altasing Human Intestine using Illumina Spatial Technology ZhuChenchen Industry Speaker United States Illumina Connected Multiomics ScmidJoachim Industry Speaker United States Auditorium VI+VII		QIAGEN: TCR Repertoires of Tumor-Infiltrating γδ1 T Cells Reveal PD-1–Modulated Reactivity TCR Repertoires of Tumor-Infiltrating γδ1 T Cells Reveal PD-1–Modulated Reactivity MikulakJoanna Industry Speaker Italy Auditorium VIII
13:30 14:15	Career Discovery Session 2A (open to EACR Early Career & Student Members, pre-registration required) Carracedo PerezArkaitz Coordinator Spain OricchioElisa Coordinator Switzerland TABLE 1: How to build your own network RisquesRosana Moderator United States TABLE 2: Leadership: Experience in combining research with the direction of a research institute BardelliAlberto Moderator Italy TABLE 3: Leadership: Experience as a team leader and a research center science director MarineJean-Christophe Moderator Belgium TABLE 4: Life of a scientist between research and hospital SomervailleTim Moderator United Kingdom TABLE 5: How to make your research impactful and transferable to the clinic GomisRoger Moderator SpainYes TABLE 6: How to build a successful lab environment WestermarckJukka Moderator Finland TABLE 7: How do you know when you are ready to start your own lab? TurajlicSamra Moderator United Kingdom TABLE 8: Challenges of setting up a new lab and establishing yourself as a PI in your home country after years abroad CorreiaAna Luisa Moderator Portugal TABLE 9: The challenges of starting your own lab VenkateshHumsa Moderator United States TABLE 10: ERC funding opportunities for starting or establishing a research group in the EU or Associated Countries CaraffiniVeronica Moderator BelgiumYes Career Discovery Area
14:25 15:15	Career Discovery Session 2B (open to EACR Early Career & Student Members, pre-registration required) Carracedo PerezArkaitz Coordinator Spain OricchioElisa Coordinator Switzerland TABLE 1: A career at the intersection between cell biology and oncology RegenbergBirgitte Moderator Denmark TABLE 2: Navigating a career in Academia and Industry PaganiMassimiliano Moderator Italy TABLE 3: Challenges of being a clinician scientist: Successfully balancing clinical and academic duties TaberneroJosep Moderator Spain TABLE 4: From fundamental science to translational impact de VisserKarin E. Moderator Netherlands TABLE 7: Current challenges in academia: tips to survive Aguirre-GhisoJulio A. Moderator United States TABLE 8: The challenges of starting your own lab MisaleSandra Moderator United States TABLE 9: Leadership: Experience of a former EACR president BernardsRene Moderator Netherlands TABLE 10: From performing research to supporting researchers: transitioning from academia to scientific administration CaraffiniVeronica Moderator BelgiumYes Career Discovery Area
14:30 15:15	Olink, part of Thermo Fisher Scientific: Plasma Proteomics: Driving a New Era for Cancer Research and Precision Medicine RUCEVICGuyonnetMarijana Industry Moderator/ Chair Sweden Olink Proteomics: Accelerating progress in cancer research and the path to therapeutics RUCEVICGuyonnetMarijana Industry Speaker Sweden Deep plasma proteomics identifies and validates an eight-protein biomarker panel for ovarian cancer EnrothStefan Industry Speaker Sweden Liquid biopsy: Plasma proteomics to identify novel biomarkers ItalianoAntoine Industry Speaker France Questions and Answers Auditorium II		NVision Imaging Technologies: Hyperpolarized MRI Agents: Visualize Cancer Metabolism - As It Happens Introduction to C13 Hyperpolarization BennettSimon Industry Speaker Germany Applications for imaging and measuring metabolism in vivo BennettSimon Industry Speaker Germany Q&A Auditorium VI+VII		Oxford Nanopore Technologies: Deciphering Cancer Evolution and Progression with Multiomic Single Cell Insights Juarez Eleonora Industry Moderator/ Chair United States Unlocking Novel Cancer Biology with Multiomic Insights, Introduction by Chair/ Moderator Juarez Eleonora Industry Moderator/ Chair United States Bridging genotype and phenotype through single-cell and single-molecule multi-omics HarbersLuuk Industry Speaker Belgium Tumour heterogeneity and clonal selection of ecDNA at single-cell level Deleuran Hendriksen Josephine Industry Speaker Denmark Auditorium VIII
15:20 16:55	Symposium: AI Tools in Cancer Research CaldasCarlos Co-Chair Israel JacquemetGuillaume Co-Chair Finland Agent-Based Modelling of Gene Networks the tumour microenvironment ecosytem BuffaMeteoraFrancesca Speaker United Kingdom Proffered Paper: High-throughput drug screening in breast cancer PDTCs enables clinically relevant drug discovery for personalised medicine. EACR25-1681 EACR25-1681 MasinaRiccardo Presenter United Kingdom The power of many: Unlocking treatment response patterns through single-cell meta-analysis (REMOTE PRESENTATION) AranDvir Speaker Israel Proffered Paper: Spatial and multi-omic profiling of HGSC to identify immune vulnerabilities for precision immunotherapy EACR25-0439 EACR25-0439 ShabanovaAleksandra Presenter Finland Harnessing computational tools to understanding somatic evolution in cancer McGranahanNicholas Speaker United Kingdom Auditorium I	Symposium: Prevention and Early Detection LimEmilia Co-Chair Canada SoengasMarisol S. Co-Chair Spain Polygenic risk models and prevention in breast and ovarian cancer PharoahPaul Speaker United States Proffered Paper: Multi-omic spatial analysis reveals reshaping of tumour-immune dynamics at the transition to invasive colorectal cancer EACR25-1604 EACR25-1604 BakerAnn-Marie Presenter United Kingdom Mechanisms of Lung Cancer Promotion HillWilliam Speaker United Kingdom Proffered Paper: Tumour genotype shapes blood biomarker expression for use in pancreatic cancer detection and diagnosis EACR25-0817 EACR25-0817 CanelMarta Presenter United Kingdom Investigating the impact of environmental exposures LimEmilia Speaker Canada Auditorium II		Symposium: DNA Repair and Immunosurveillance BardelliAlberto Co-Chair Italy DiazLuis Alberto Co-Chair United States DNA repair-dependent immunogenic liabilities in colorectal cancer: the opportunity comes from the errors GermanoGiovanni Speaker Italy Proffered Paper: Exploit Neutrophil Heterogeneity to induce Synthetic Lethality in Breast Cancer EACR25-0256 EACR25-0256 CalcinottoArianna Presenter Switzerland Immunoprevention in Lynch Syndrome DiazLuis Alberto Speaker United States Proffered Paper: Intratumoral STING pathway activation enhances anti-tumor immune responses and therapeutic efficacy of ATR inhibition. EACR25-0468 EACR25-0468 SenTriparna Presenter United States Know Your Enemy: Unraveling the Gene Regulatory Networks of Tumor-Infiltrating CD4+ Regulatory T Cells PaganiMassimiliano Speaker Italy Auditorium VI+VII		Symposium: EC DNA DiveCaroline Co-Chair United Kingdom DiasHenriqueMatheus Co-Chair NetherlandsYes Extrachromosomal DNA (ecDNA): Cancer’s Dynamic Circular Genome MischelPaul Salomon Speaker United States Proffered Paper: Heterogeneous oncogene dosage driven by extrachromosomal DNA determines neuroblastoma response to therapy EACR25-0364 EACR25-0364 MontuoriGiulia Presenter Germany Functional Role of Extrachromosomal Circular DNA in Colorectal, Renal and Bladder Cancers RegenbergBirgitte Speaker Denmark Proffered Paper: Investigating the impact of extrachromosomal DNA amplification on cell fate decisions and therapy resistance EACR25-2262 EACR25-2262 SchmargonRachel Presenter Germany A general strategy to model ecDNA-mediated focal amplifications in cells and in mice VenturaAndrea Speaker United States Auditorium VIII
16:55 17:30	Coffee Break / Exhibition / Industry Spotlight Poster and Exhibition Hall
17:15 17:30	Cellecta Inc. Industry Spotlight: TCR/BCR Repertoire Profiling and other Approaches for Drug Target and Biomarker Discovery ChenchikAlex Industry Speaker United States A practical guide for adaptive immune receptor repertoire profiling and the characterization of antigen-induced clonotypes with applications in cancer, vaccine development, and autoimmunity ChenchikAlex Industry Speaker United States Spotlight Theatre
17:30 18:15	Plenary Session - From Bench to Bedside and Back BardelliAlberto Chair Italy BernardsRene Co-Chair Netherlands Clinical findings in preclinical perspective BardelliAlberto Speaker Italy BernardsRene Speaker Netherlands Introduction on PFS and OS of the BREAKWATER study (1st line) TaberneroJosep Speaker Spain Clinical Development Saoudi GonzálezNadia Speaker Italy Auditorium I
18:15 18:40	Posters in the Spotlight - Wednesday DiasHenriqueMatheus Moderator NetherlandsYes Dissecting ovarian cancer cellular responses to radioimmunotherapy with β- particle and ultra-short range conversion and Auger electron-emitting radionuclides. (EACR25-0133) P-552 EACR25-0133 GrzmilMichal Presenter Switzerland Pan-cancer analysis of successive whole genome duplication in the 100,000 Genomes Project (EACR25-0555) P-746 EACR25-0555 SmythEvie Presenter Ireland COX-2/PGE2 Activity in Cancer Cells: A Key Driver of Metastasis via Immune Escape (EACR25-0743) P-773 EACR25-0743 RussoMassimo Presenter United Kingdom Depleting tumour-infiltrating Tregs to enhance the efficacy of KRAS-mutant targeted therapies in lung cancer (EACR25-1513) P-790 EACR25-1513 de CastroAndrea Presenter United Kingdom Cytotoxic ILC-1 cells determine outcome of PD-(L)1 blockade in microsatellite instable cancers (EACR25-2039) P-522 EACR25-2039 Van RoyenPaula Presenter Netherlands Spotlight Theatre
18:40 20:00	Poster Defence Session - Wednesday
10:45 20:00	Poster Session Wednesday Poster and Exhibition Hall			Poster Session Wednesday - LATE ABSTRACTS Poster and Exhibition Hall