Search Programme

Cancer Researchers to watch - An early career showcase

Time	Session

14:00 15:40	Cancer Researchers to watch - An early career showcase (Separate pre-registration required) BaggioliniArianna Chair Switzerland Welcome Message CaffarelMaria M. Chair Spain FAK Inhibition Promotes Critical Cytotoxic Interactions Between CD8 T Cells and Cancer Cells in Metastatic Breast Cancer BarthNicole Speaker United Kingdom Proffered Paper 1: Inhibition of Furin in CAR macrophages directs them toward a proinflammatory phenotype and enhances their antitumor activities ZIANE CHAOUCHE Lydia Presenter France Proffered Paper 2: Multimodal analysis of spatial transcriptomics data uncovers novel invasive lobular carcinoma subtypes SerraMatteo Presenter Belgium Targeting cytokine signalling to block cancer-promoting inflammation and tumour progression CaffarelMaria M. Speaker Spain Auditorium VIII
15:40 16:10	Refreshment Break
16:10 17:40	Cancer Researchers to watch - An early career showcase (Separate pre-registration required) JacquemetGuillaume Chair Finland Reprogramming immunosuppressive tumor-associated macrophages potentiates standard-of-care therapy in melanoma TichetMelanie Speaker Switzerland Proffered Paper 3: SoxC transcription factors are oncoembryonic regulators of colon development and cancer DalessiTosca Presenter Switzerland Proffered Paper 4: Erythrocyte-derived sphingosine-1-phosphate promotes tumor cell survival in the circulation VuceticAdriana Presenter Germany Therapeutic OVERactivation of oncogenic signaling as a cancer treatment strategy dos Santos DiasMatheus Speaker The Netherlands Auditorium VIII
17:40 18:30	Meet the ECR Council - Panel Discussion (Separate pre-registration required) Auditorium VIII
18:30 20:00	Early Career Networking Reception (Separate pre-registration required) Main Foyer

Monday, 16 June 2025

Time	Session

08:15 14:00	Women in Leadership (Separate pre-registration required) Offsite Venue
08:30 10:00	Cancer Researchers to watch - An early career showcase (Separate pre-registration required) CaffarelMaria M. Chair Spain Exploiting metabolic vulnerabilities to improve breast cancer therapy MorandiAndrea Speaker Italy Proffered Paper 5: Melting the Iceberg: Nanomedicines Overcoming Stromal Barriers and Recruiting Effector T Cells in Pancreatic Cancer AcúrcioCRita Presenter Portugal Proffered Paper 6: ENO3PEP vaccine enhances chemotherapy efficacy in pancreatic cancer by boosting anti-tumor immunity BrugiapagliaSilvia Presenter Italy Stem cells-based models of tumor initiation and metastasis BaggioliniArianna Speaker Switzerland Refreshment Break Auditorium VIII
10:20 12:00	ASPIC - EACR Joint Symposium BardelliAlberto Co-Chair Italy JerónimoCarmen Co-Chair Portugal γδ T Cells in Cancer and Cancer Immunotherapy SantosBruno Silva Speaker Portugal Zebrafish Cancer Avatars for Clinical Decision-making FiorRita Speaker Portugal IL-7 and IL-7R: Subverting Lymphoid Development Towards Leukemia BarataJoão T. Speaker Portugal Association Between CDH1 Germline Variants and Cancer Phenotypes OliveiraCarla Speaker Portugal Questions & Answers Auditorium VI+VII
10:30 12:00	Cancer Researchers to watch - An early career showcase (Separate pre-registration required) dos Santos DiasMatheus Chair The Netherlands Attaching to and Crossing Endothelial Barriers JacquemetGuillaume Speaker Finland Proffered Paper 7: CD24-mediated differential platelets-tumor cells binding tunes metastatic progression LiboniCristina Presenter France Proffered Paper 8: Microfluidic Single-Cell Profiling in Prostate Cancer Bone Metastasis Reveals Ultra-Migratory Subpopulations, Tumour-Bone Crosstalk and CTC Heterogeneity. CottonThomasDaniele Presenter United Kingdom Omomyc is a promising anti-MYC therapy for pediatric medulloblastoma EscuderoLaura Speaker Canada Auditorium VIII			Meet the Award Winners - Interactive Session GalligioniEnzo Moderator Italy BishRebecca Moderator United States Immune Conversations in Cancer—and Why Every Voice Counts The Pezcoller-Marina Larcher Fogazzaro-EACR Women in Cancer Research Award 2025 de VisserKarin E. Speaker Netherlands Lessons from Senescence: Using our model systems as a guide to life EACR-Mark Foundation-Pezcoller Foundation Rising Star Award 2025 KovatchevaMarta Speaker Italy The Power of ONE: Why Now Is the Most Exciting Time to Be in Cancer Research The Pezcoller Foundation-EACR Translational Cancer Researcher Award 2025 AmitIdo Speaker Israel Discussion with the Experts Career Discovery Area
12:00 14:00	Lunch Break / Exhibition Main Foyer
12:15 13:00	biomodal: Investigating the role of the 6-base genome within the field of Cancer Research with a focus on breast and prostate cancer CharlesworthTom Industry Moderator/ Chair United Kingdom Introduction CharlesworthTom Industry Moderator/ Chair United Kingdom Unlocking Hidden Signals: A multimodal approach to ctDNA detection in early prostate cancer SadeghiHanieh Industry Speaker Austria Characterisation of Advanced BC Subtypes in cfDNA by methylation profiling CuttsRos Industry Speaker United Kingdom Auditorium VI+VII			Bruker Spatial Biology: Expanding the Limits of Biology: Comprehensive Integrated Technologies for Multiomics in Oncology SheehyKevin Industry Moderator/ Chair United States Introduction SheehyKevin Industry Moderator/ Chair United States Industry-Leading Spatial Solutions for High-Plex Multiomic Tissue Exploration and Discovery KoenigChristoph Industry Speaker Germany Streamlining Next-Gen Spatial Proteomics with EpicIF™ Technology and the PowerOMX™ Engine BraubachOliver Industry Speaker United States Sub-cellular, multiomic imaging of the entire protein-coding transcriptome (18936-plex RNA) and 75-plex Protein on a single-slide FFPE tissue section using CosMx Spatial Molecular Imaging LyssandJohnny Industry Speaker United States Auditorium VIII
13:15 14:00	10x Genomics: See Biology in new Ways - Single Cell and Spatial Transcriptomic Methods to Understand Cancer MayClaudia Industry Moderator/ Chair United States Introduction MayClaudia Industry Moderator/ Chair United States Spatial immune landscape of cutaneous squamous cell carcinomas (cSCC) prior to immune checkpoint blockade ReschkeRobin Industry Speaker Germany Improving Immunotherapy Strategies Through Single-Cell Profiling of Lung Cancer BischofPhilip Industry Speaker Germany Auditorium VI+VII			Standard BioTools: Spatial Predictors of Immunotherapy Response in Triple-Negative Breast Cancer SpadaRoberto Industry Moderator/ Chair Introduction SpadaRoberto Industry Moderator/ Chair Spatial Predictors of Immunotherapy Response in Triple-Negative Breast Cancer GiampaoloBianchini Industry Speaker Italy Auditorium VIII
14:00 15:15	Top Abstracts Carracedo PerezArkaitz Co-Chair Spain SalvadorBeatriz Co-Chair United Kingdom Proffered Paper: IL-1R8 acts as an immune checkpoint in CD8+ T cells, limiting cytokine-induced anti-tumor immune responses EACR25-1517 EACR25-1517 GarutiRoberto Presenter Italy Proffered Paper: Genome-Wide CRISPR Screening Identifies Lipid-Sensing Chemosensor Receptors as Regulators of Tumor-Associated Macrophage Function in Cancer EACR25-1932 EACR25-1932 MarelliGiulia Presenter Italy Proffered Paper: A novel spatial DNA sequencing method for the detection of somatic mutations from hundreds of regions in archival tissue sections EACR25-2439 EACR25-2439 RaoRaoSrinivasa Presenter United Kingdom Proffered Paper: Oncostatin M cytokine signalling orchestrates immune remodelling and metabolism within the breast tumour microenvironment EACR25-0851 EACR25-0851 AzcoagaPeio Presenter Spain Proffered Paper: 177Lu-Trastuzumab as a promising therapy for resistant brain metastases in HER2+ breast cancer EACR25-1471 EACR25-1471 SantosLiliana Presenter Portugal Auditorium I		Award Winners Special Session OricchioElisa Co-Chair Switzerland CohenMerav Co-Chair Israel Introduction of the Mark Foundation BishRebecca Presenter United States 2025 EACR-Mark Foundation -Pezcoller Foundation Rising Star Award Lecture: Unravelling cell plasticity in tumor initiation and progression KovatchevaMarta Award Lecture Italy Introduction AstraZeneca Fellowship and Award OricchioElisa Presenter Switzerland EACR - AstraZeneca Postdoctoral Fellowship Award Lecture: Targeting immunosuppression induced by oncogenic PI3K/AKT signalling to enhance anti-tumour immunity in breast cancer van WeverwijkAntoinette Award Lecture The Netherlands Introduction Boehringer Ingelheim Fellowship and Award HofmannMarco Presenter Austria EACR - Boehringer Ingelheim Postdoctoral Fellowship Award Lecture: Implications of one carbon metabolism in cancer cell proliferation and metastasis KiwelerNicole Award Lecture Luxembourg Auditorium II		Joint EACR - EACS - Molecular Oncology Session: Keep Research Curious RyanKevin Co-Chair United KingdomMolecular Oncology BernardsRene Co-Chair Netherlands DNA damage, cancer and aging and the unexpected impact of nutritional interventions HoeijmakersJan H. Speaker Multimodal, Generative, and Agentic AI for Pathology MahmoodFaisal Speaker United States Decoding the Cancer Connectome of Brain Tumor Networks VenkataramaniVarun Speaker Germany Auditorium VI+VII
15:15 15:45	Meet and Greet EACR Ambassador and Solo Travellers EACR Stand			Coffee Break / Exhibition Poster and Exhibition Hall
15:45 18:15	EACR 2025 Congress - Opening Session Opening Address SamuelsYardena Chair Israel Introduction of Keynote Speaker SamuelsYardena Chair Israel Myeloid Mayhem: Inflammation driven Lung Cancer initiation and progression SwantonCharles Keynote Speaker United Kingdom Pezcoller Award Presentation and Introduction of the Award Recipients GalligioniEnzo Presenter Italy The Pezcoller Foundation-EACR Translational Cancer Researcher Award 2025 - Leveraging single cell technologies to engineer the immune system (REMOTE PRESENTATION) AmitIdo Award Lecture Israel The Pezcoller-Marina Larcher Fogazzaro-EACR Women in Cancer Research Award 2025 - Dissecting Tumor-Immune Crosstalk in Cancer Progression and Therapy de VisserKarin E. Award Lecture Netherlands Auditorium I
18:15 18:30	EACR General Assembly and Awards Ceremony (EACR Members only) (18:15 - 18:30) Auditorium I			Welcome Reception (18:15 - 20:00) Poster and Exhibition Hall
18:45 19:00	Stilla Technologies Industry Spotlight: Setting the stage for microRNA signatures in clinical practice – multiplexed microRNA analysis with digital PCR TostJorg Industry Speaker France Spotlight Theatre
19:15 19:30	Agilent Technology Industry Spotlight: Powering Breakthroughs in Cancer and Immunotherapy with Agilent Integrated Technologies GabrieleStefano Industry Speaker Italy Spotlight Theatre

Thursday, 19 June 2025

Time	Session

09:00 09:15	Special Lecture SamuelsYardena Co-Chair Israel Align, Act, Accelerate – the future of European Research (REMOTE Presentation) HeitorManuel Speaker Portugal Auditorium I
09:15 10:00	Keynote Lecture JoyceJohanna A Chair Switzerland The Role of Plasticity in Tissue Remodeling and Tumor Progression Pe'erDana Keynote Speaker United States Auditorium I
10:00 11:15	Meet the Editors Panel Discussion BardelliAlberto Moderator Italy DiveCaroline Moderator United Kingdom Panel Discussion ZaromytidouAlexia-Ileana Panel United StatesNature Cancer AlfaranoGabriele Panel GermanyGenome Medicine TurkHarmony Panel United StatesCancer Research SiuI-Mei Panel United StatesCancer Discovery TanJiaying Panel ChinaCell RyanKevin Panel United KingdomMolecular Oncology KellyPriscilla Panel United StatesScience MaoSteve Panel United StatesCancer Cell Auditorium I
11:15 11:30	Coffee Break Main Foyer
11:30 12:15	Keynote Lecture BernardsRene Chair Netherlands Uncovering and targeting the mechanisms regulating tumor plasticity BlanpainCedric Keynote Speaker Belgium Auditorium I
12:15 12:20	Break Main Foyer
12:20 13:10	Keynote Lecture & Closing Remarks SamuelsYardena Chair Israel ‘The EMBO Keynote Lecture’: Modelling breast cancers in space and time CaldasCarlos Keynote Speaker United Kingdom EACR 2025 - Closing Remarks SamuelsYardena Chair Israel Auditorium I

Tuesday, 17 June 2025

Time	Session

08:30 09:15	Thermo Fisher Scientific: Advancing Cancer Research through Innovations in Spatial Proteomics and Imaging Technologies Introduction to the Invitrogen™ EVOS™ S1000 Spatial Imaging System GrespiFrancesca Industry Speaker Spatial Proteomics: Transforming Our Understanding of Cancer Biology StadlerCharlotte Industry Speaker Sweden Navigating Challenges in Spatial Proteomics from an Imaging Core facility perspective Carolina Oses Industry Speaker Questions and Answers Auditorium II				Bruker Cellular Analysis: Experience Live Single-Cell Functional Insights with Beacon Discovery for Oncology & Immunotherapy Research Experience Live Single-Cell Functional Insights with Beacon Discovery for Oncology & Immunotherapy Research SantosTiago Industry Speaker United States ZhangYan Industry Speaker United States Experience Live Single-Cell Functional Insights with Beacon Discovery for Oncology & Immunotherapy Research Experience Live Single-Cell Functional Insights with Beacon Discovery for Oncology & Immunotherapy Research Presentation Title - TBD SchmidtPatrick Industry Speaker Germany Questions and Answers Auditorium VI+VII				Meet the Expert - Interactive Session LianidouEvi Moderator Greece Multi-Omic Profiling for Precision Pediatric Cancer Diagnosis MardisElaine R. Speaker United States Discussion & Questions Career Discovery Area
09:20 10:55	Symposium: Next-generation Immunotherapy Modalities SamuelsYardena Co-Chair Israel Engineered dendritic cell therapy De PalmaMichele Speaker Switzerland Proffered Paper: Synergistic effect of thiopurine 6TG and immunocheckpoint blockade to inhibit melanoma growth EACR25-0734 EACR25-0734 De ZioDaniela Presenter Denmark Exploiting immune surveillance to target colorectal cancer BardelliAlberto Speaker Italy Proffered Paper: Systematic identification of recurrent immunogenic neoantigens in treatment-resistant tumors EACR25-2222 EACR25-2222 GumpertNofar Presenter Israel Translation Dysregulation In Cancer as a Source for Targetable Antigens SamuelsYardena Speaker Israel Auditorium I				Symposium: Brain Metastasis BaggioliniArianna Co-Chair Switzerland JoyceJohanna A Co-Chair Switzerland Identifying and targeting metabolic vulnerabilities in leptomeningeal metastasis BoireAdrienne Speaker United States Proffered Paper: Reshaping Tumor-Vascular-Immune Crosstalk by VEGFR-3 Modulation in Breast Cancer Brain Metastases EACR25-1283 EACR25-1283 MacelaCarolina Presenter Portugal Strategies to challenge brain metastases in mice and human ValienteManuel Speaker Spain Proffered Paper: Loss of Kmt2c or Kmt2d drives brain metastasis via KDM6A-dependent upregulation of MMP3 EACR25-1678 EACR25-1678 SeehawerMarco Presenter United States Unraveling the Complexity of Cancer Ecosystems JoyceJohanna A Speaker Switzerland Auditorium II				Symposium: Early Onset Cancers EngCathy Co-Chair United States dos Santos DiasMatheus Co-Chair The Netherlands Genomic epidemiology approaches to elucidate the causes of Early onset colorectal cancer globally Perdomo VelasquezSandra Speaker France Proffered Paper: Geographic and age-related variations in mutational processes in colorectal cancer EACR25-1102 EACR25-1102 Díaz-GayMarcos Presenter Spain More Than Mutations: A Survival Guide for Nascent Tumours AlcoleaMaria Pilar Speaker United Kingdom Proffered Paper: Fibroblast specific endoglin deletion increases colorectal cancer tumorigenesis in a subset-specific manner EACR25-1472 EACR25-1472 AbudukelimuSubinuer Presenter Netherlands The burgeoning horizon of early-onset GI cancers EngCathy Speaker United States Auditorium VI+VII
10:55 11:35	Coffee Break / Exhibition / Industry Spotlight Poster and Exhibition Hall
11:15 11:30	Cell Signaling Technology Industry Spotlight: Empowering Cancer Research with Award-Winning Technologies from CST: SignalStar® Multiplex IHC and InTraSeqTM Single Cell Analysis JacquetMaxime Industry Speaker Netherlands Empowering Cancer Research with Award-Winning Technologies from CST: SignalStar® Multiplex IHC and InTraSeqTM Single Cell Analysis JacquetMaxime Industry Speaker Netherlands Spotlight Theatre
11:35 13:10	Symposium: Clinical Cancer Biomarkers DiveCaroline Co-Chair United Kingdom EscuderoLaura Co-Chair Canada New Insights into the Impact of the Tumor Microbiome on Immunotherapy Response (REMOTE PRESENTATION) StrausmannRavid Speaker Israel Proffered Paper: Epigenetic regulation shapes the tumor microenvironment in NSCLC and impacts the outcome of immune checkpoint blockade therapy EACR25-0504 EACR25-0504 Gallardo-GómezMaría Presenter Spain Optimal Outcome for High-risk Breast Cancer by Response Predictive Biomarkers Van't VeerLaura Speaker United States Proffered Paper: Monitoring genetic and epigenetic evolution of metastatic colorectal cancer through longitudinal ctDNA profiling EACR25-0818 EACR25-0818 chemifrancesca Presenter Italy The Immune Contexture Concept and Clinical Utility GalonJerome Speaker France Auditorium I			Symposium: Clonal Hematopoiesis TrumppAndreas Co-Chair Germany dos Santos DiasMatheus Co-Chair The Netherlands Quantitative insights into somatic evolutionary dynamics in healthy and pre-malignant blood BlundellJamie Speaker United Kingdom Proffered Paper: Unveiling the role of migratory dendritic cells in liver cancer EACR25-0607 EACR25-0607 VolponiCamilla Presenter Italy Clonal Hematopoiesis and Cancer BernardElsa Speaker France Proffered Paper: Bulk and spatial B cell receptor repertoire analysis to characterize antibody maturation in relation to tertiary lymphoid structures and response to immunotherapy EACR25-2072 EACR25-2072 PupierGuilhem Presenter France Panel Discussion Auditorium II			Symposium: Molecular Mechanisms of Metastasis JacquemetGuillaume Co-Chair Finland Aging Stroma Drives Breast Cancer Progression StewartA.Sheila Speaker United States Proffered Paper: Circulating tumor cells shed a new class of shearosome large extracellular vesicles in capillary bifurcations that drive metastatic processes EACR25-0080 EACR25-0080 AuSam Presenter United Kingdom Cancer – Matrix Crosstalk in Cancer Progression IvaskaJohanna Speaker Finland Proffered Paper: Cockle transmissible cancers characterized by horizontal transfers and instability of mitogenomes EACR25-0182 EACR25-0182 BRUZOSAlicia L. Presenter France Targeting the metastatic microenvironment IsackeClare Speaker United Kingdom Auditorium VI+VII			Symposium: RNA Biology in Cancer SflomosGeorgios Co-Chair Switzerland Mechanisms of cell plasticity in breast cancer (REMOTE Presentation) VallotCeline Speaker France Proffered Paper: Transcriptional state transitions link tissue injury and early carcinogenesis in the kidney EACR25-0509 EACR25-0509 HirosueShoko Presenter United Kingdom Targeting lineage plasticity in castration resistant prostate cancer KarthausWouter Speaker Switzerland Proffered Paper: SpliceSeek: a CRISPR-based platform for uncovering T-cell alternative splicing isoforms for immunotherapy EACR25-1366 EACR25-1366 TzabanShay Presenter Israel Tissue-specific transcriptional vulnerabilities in cancer VanharantaSakari Speaker Finland Auditorium VIII
13:15 15:15	Lunch Break / Exhibition / Poster Viewing Poster and Exhibition Hall
13:30 14:15	Illumina Inc.: Empowering discoveries across omics BabayanAnna Industry Moderator/ Chair Germany Introduction to multiomics BabayanAnna Industry Moderator/ Chair Germany Rapid WGS with Constellation read map technology for paediatric cancer research VediAditi Industry Speaker United Kingdom Identification of biomarkers for early detection of colorectal cancer: multiomic, epigenetic and metagenomic analysis of rectal mucus sampling WiseDaniel Industry Speaker United Kingdom BreakThrough Spotlight – Early Career Researcher Unravelling Tumour Genetics: The Role of cfDNA Whole-Exome Sequencing in Treatment Response Assessment SerioViola Bianca Industry Speaker Italy Q&A and panel discussion Auditorium II			Miltenyi Biotec: Spatial biology for studying tumor microenvironment: paving the way for immunotherapy approaches SchalénMartin Industry Moderator/ Chair Sweden Characterization of a novel cancer-associated fibroblast population with immunosuppressive functions Pfeifer Rita Industry Speaker Germany Multiplexed Imaging-Powered Deep Visual Proteomics (mipDVP) ZhengXiang Industry Speaker Denmark Questions and Answers Auditorium VI+VII			Bio-Rad Laboratories Ltd.: Innovating Cancer Science with ddPCR BianchiMarco Giorgio Industry Moderator/ Chair Italy Introduction BianchiMarco Giorgio Industry Moderator/ Chair Italy Role of cfDNA and ctDNA to improve the risk stratification and the disease follow-up in patients with endometrial cancer Muinelo RomayLaura Industry Speaker Spain Detection rate for ESR1 mutations is higher in CTC-derived genomic DNA than in paired plasma cell-free DNA samples as revealed by ddPCR NtzifaAliki Industry Speaker Greece Questions and Answers Auditorium VIII			Speed-Networking Event for Early-Career Attendees (Fully Booked) (open to EACR Early Career & Student Members, pre-registration required) Career Discovery Area
14:25 15:15	Career Discovery Session 1A (open to EACR Early Career & Student Members, pre-registration required) Carracedo PerezArkaitz Coordinator Spain OricchioElisa Coordinator Switzerland TABLE 1: Efficient and caring mentorship: how to make your research team flourish? JoyceJohanna A Moderator Switzerland TABLE 2: Leadership: Experience of a former EACR president DiveCaroline Moderator United Kingdom TABLE 3: Building Equitable Research Careers for Women IvaskaJohanna Moderator Finland TABLE 4: How to make your research transferable to the clinic ValienteManuel Moderator Spain TABLE 6: Challenges of starting a new lab and becoming a PI abroad AlcoleaMaria Pilar Moderator United Kingdom TABLE 7: Experiences and Insights from a Pharmaceutical Research Career HofmannMarco Moderator Austria TABLE 8: The challenges of opening your own lab KarthausWouter Moderator Switzerland TABLE 9: ERC funding opportunities for starting or establishing a research group in the EU or Associated Countries CaraffiniVeronica Moderator TABLE 10: Lessons from My Journey: Navigating Data Science & Bioinformatics Careers in Pharma SinaNassiri Moderator Switzerland Career Discovery Area
14:30 15:15	Lunaphore, a Bio-Techne brand: Advancing oncology research with spatial biology One platform and endless possibilities for immuno-oncology research KowalJoanna Industry Speaker Switzerland Exploring the Spatial Biology of Colorectal Cancer Liver Metastases FichtXenia Maria Industry Speaker Switzerland Auditorium II				PromoCell GmbH: A toolbox for cancer stem cell selection ScheidLisa-Mareike Industry Moderator/ Chair Germany Introduction by Moderator ScheidLisa-Mareike Industry Moderator/ Chair Germany How to kill your fibroblasts and save the cancer stem cells in your culture TrampeAlexander Industry Speaker Germany PromoCell’s Cancer Media Toolbox TrampeAlexander Industry Speaker Germany Questions & Answers Auditorium VI+VII				Element Biosciences: Leveraging high dimensional multiomic screens with AVITI24™ to accelerate drug discovery van IjckenWilfred Industry Moderator/ Chair LEVERAGING HIGH DIMENSIONAL MULTIOMIC SCREENS WITH AVITI24™ TO ACCELERATE DRUG DISCOVERY van IjckenWilfred Industry Speaker SENSITIVE CFDNA BIOMARKER IDENTIFICATION BY TARGETED SEQUENCING FROM PLASMA AND URINE SAMPLES NelIvonne Industry Speaker Germany Auditorium VIII
15:20 16:55	Symposium: Immune Cell Heterogeneity in the Cancer Ecosystem SflomosGeorgios Co-Chair Switzerland Charting the intact breast tumour microenvironment AliRaza Speaker United Kingdom Proffered Paper: Characterization of a population of CD4⁻ CD8⁻ Double-Negative T Cells with anti-tumor properties EACR25-1514 EACR25-1514 Di CeglieIrene Presenter Italy Stromal and immune plasticity shape the metastatic microenvironment (REMOTE PRESENTATION) ErezNeta Speaker Israel Proffered Paper: Rewiring T Cell Networks to Overcome Immune Evasion in Ovarian Cancer Relapse EACR25-2250 EACR25-2250 DANGAJ LANITIDENARDA Presenter Switzerland The Power of ONE: Immunology in the Age of Spatial and Single-Cell Genomics (REMOTE PRESENTATION) AmitIdo Speaker Israel Auditorium I			Symposium: Senescence in Therapy Response TrumppAndreas Co-Chair Germany dos Santos DiasMatheus Co-Chair The Netherlands Harnessing senescence biology for immune oncology (REMOTE Presentation) LoweScott Speaker United States Proffered Paper: Targeting senescent macrophages inhibits metastatic dissemination in adrenocortical cancer EACR25-0260 EACR25-0260 ValPierre Presenter France Controlling therapy-induced senescence: novel approaches to senolysis KovatchevaMarta Speaker Italy Proffered Paper: Therapy-Induced Senescence Promotes Immunogenicity in Acute Myeloid Leukemia Blasts through loss of PRC2-Mediated Regulation EACR25-0844 EACR25-0844 FuscoSimona Presenter Italy Plasticity of Leukemic Stem Cells TrumppAndreas Speaker Germany Auditorium II			Symposium: Non-invasive Diagnostics MouliereFlorent Co-Chair United Kingdom EscuderoLaura Co-Chair Canada Detection of Cancer with Liquid Biopsy PapadopoulosNickolas Speaker United States Towards multi-modal liquid biopsies MouliereFlorent Speaker United Kingdom Proffered Paper: KRAS pharmacological blockade elicits tumoral homologous recombination deficiency exploitable with PARP inhibitors EACR25-0812 EACR25-0812 VicentSilvestre Presenter Spain A DNA methylation atlas of normal human cell types (REMOTE PRESENTATION) KaplanTommy Speaker Israel Questions & Answers Auditorium VI+VII			Symposium: Novel Models of Cancer Cachexia Carracedo PerezArkaitz Co-Chair Spain Modeling cachexia in mice: from intestinal cancer models to distinct host trajectories PennaFabio Speaker Italy Proffered Paper: Oncolytic virus (CVA21) in combination with pembrolizumab increases tumour cell immunogenicity and remodels the tumour microenvironment in advanced NSCLC: a phase I/II trial EACR25-1995 EACR25-1995 BalasubramanianAdithya Presenter Australia Insights into cancer cachexia from the TRACERx lung cancer study Jamal-HanjaniMariam Speaker United Kingdom Proffered Paper: Translational control shapes Treg cell fate in the tumor microenvironment EACR25-2124 EACR25-2124 OlivetoStefania Presenter Italy Exploring the tumor MACROenvironment for improving cancer diagnosis and therapy (REMOTE PRESENTATION) ErezAyelet Speaker Israel Auditorium VIII
16:55 17:30	Coffee Break / Exhibition / Industry Spotlight Poster and Exhibition Hall
17:15 17:30	Parse Biosciences Industry Spotlight: Redefining Single Cell RNA Sequencing Limits with Evercode Combinatorial Barcoding ScocchiaDanniela Industry Speaker Spain Redefining Single Cell RNA Sequencing Limits with Evercode Combinatorial Barcoding As single cell technologies have advanced, assay scalability has become a critical factor in capturing the full heterogeneity and complexity of biological systems. With its combinatorial barcoding platform, Evercode, Parse continues to redefine the limits of single cell research. Join us for our spotlight presentation to learn about the latest updates to Evercode, including the launch of Evercode WT Penta, for profiling of up to 5 million cells and up to 384 samples in a single run. ScocchiaDanniela Industry Speaker Spain Spotlight Theatre
17:30 18:15	Keynote Lecture BardelliAlberto Chair Italy Cancer Metabolism WhiteEileen Keynote Speaker United States Auditorium I
18:15 18:40	Posters in the Spotlight - Tuesday Fishing for new immunotherapy compounds to boost innate-tumor rejection (EACR25-0448) P-450 EACR25-0448 MachadoBeatrizAna Presenter Portugal Ovarian cancer Zebrafish Avatars for personalized multiple drug testing (EACR25-0644) P-553 EACR25-0644 EstradaFalcãoMarta Presenter Portugal Senescence Induction Sensitizes Hepatocellular Carcinoma Cells to Immunotherapy (EACR25-1308) P-156 EACR25-1308 MaXuhui Presenter China Longitudinal Dynamics of Transcriptome and Chromatin Accessibility in Ovarian High‐Grade Serous Carcinoma (EACR25-1912) P-730 EACR25-1912 AfentevaDaria Presenter Finland Neutrophil serine proteases alter IL-18 to a superkine (EACR25-2188) P-479 EACR25-2188 WöhrAnne Presenter Sweden Spotlight Theatre
18:40 20:00	Poster Defence Session - Tuesday
10:45 20:00	Poster Session Tuesday Poster and Exhibition Hall						Poster Session Tuesday - LATE ABSTRACTS Poster and Exhibition Hall

Wednesday, 18 June 2025

Time	Session

08:30 09:15	EditCo Bio: Uncovering Novel Cancer Therapeutic Targets: Accelerating Discovery Through Streamlined CRISPR Cell Engineering HardcastleTravis Industry Moderator/ Chair United States Introduction HardcastleTravis Industry Moderator/ Chair United States Unveiling SURF2’sRole in Nucleolar Stress and Its Potential as a Therapeutic Target LebaronSimon Industry Speaker France AI-driven identification and validation of novel synthetic lethal gene pairs MillerDaniel Industry Speaker United Kingdom Leveraging an advanced CRISPR platform to streamline oncology breakthroughs SoenensAmalia Industry Speaker Auditorium II				Arima Genomics: Transposable elements reorganise the 3D genome structure in CDK4/6 inhibitors resistant breast cancer Transposable elements reorganise the 3D genome structure in CDK4/6 inhibitors resistant breast cancer. Achinger-KaweckaJoanna Industry Speaker Australia Auditorium VI+VII				Meet the Expert - Interactive Session TrumppAndreas Moderator Germany Advancing Science Through Industry-Academic Collaboration: Pre-Clinical Development of KRAS Modulators HofmannMarco Speaker Austria Tumor Archetypes Reimagined: Multi-Omic Insights, AI-Driven Discovery, and New Frontiers in Cancer Subtyping SinaNassiri Speaker Switzerland Discussion with the Experts Career Discovery Area
09:20 10:55	Symposium: New Drugs on the Horizon WestermarckJukka Co-Chair Finland CaffarelMaria M. Co-Chair Spain Drugging transcription factors: HSF1 and Brachyury WorkmanPaul Speaker United Kingdom Proffered Paper: Inhibition of WEE1 kinase activity to overcome secondary resistance to targeted therapies in colorectal cancer EACR25-0376 EACR25-0376 ArenaSabrina Presenter Italy Targeting chromatin proteins for therapeutic benefit in haematological malignancy SomervailleTim Speaker United Kingdom Proffered Paper: Reversing Acidic Immune Suppression in Cancer with PTT-4256, A First-In-Class Small Molecule Inhibitor of GPR65 EACR25-0553 EACR25-0553 CorbinAlastair Presenter United Kingdom PP2A inhibitor protein CIP2A is a prime target for TNBC therapy WestermarckJukka Speaker Finland Auditorium I				Symposium: Tumour Innervation BaggioliniArianna Co-Chair Switzerland WinklerFrank Co-Chair Germany The neural regulation of small cell lung cancer progression VenkateshHumsa Speaker United States Proffered Paper: Medullary sinus macrophages limit cancer therapy efficacy by an efferocytosis-induced IL-33/ST2 axis in the tumor-draining lymph node. EACR25-1319 EACR25-1319 LamorteSara Presenter Canada Neural mechanisms of brain tumor growth and resistance WinklerFrank Speaker Germany Proffered Paper: Spatially Resolved Analysis of Cancer-Infiltrated Nerves Identifies DRAXIN as a Marker of Injury Response with Tumor-Suppressive Potential EACR25-1355 EACR25-1355 OzgaJoannaAleksandra Presenter Switzerland Neural-tumour communication accelerates cancer progression and impairs treatment response SloanErica Speaker Australia Auditorium II				Symposium: Normal Tissue (not Blood) SalvadorBeatriz Co-Chair United Kingdom RisquesRosana Co-Chair United States Clonal evolution of cancer from initiation to metastasis in the mouse (REMOTE Presentation) BalmainAllan Speaker United States Proffered Paper: Pancreatic Cancer Initiation: Wnt Signalling and Cell Dormancy Enable Kras Mutant Cell Survival EACR25-0647 EACR25-0647 SalvadorBeatriz Presenter United Kingdom PEDIA-BRAIN: Building a normal brain tissue development encyclopedia as a comparator for pediatric CNS malignancies MardisElaine R. Speaker United States Proffered Paper: Dietary Histidine controls intestinal stem cell activity, providing a potential protective role against colorectal cancer EACR25-0457 EACR25-0457 BiehlerCornélia Presenter Finland Somatic evolution in normal tissues and cancer risk RisquesRosana Speaker United States Auditorium VI+VII
10:55 11:35	Coffee Break / Exhibition/ Industry Spotlight Poster and Exhibition Hall
11:15 11:30	TECAN Industry Spotlight: Label-free spheroids and organoids analysis for assays development VettoreNicola Industry Speaker Germany Label-free spheroids and organoids analysis for assays development VettoreNicola Industry Speaker Germany Spotlight Theatre
11:35 13:10	Symposium: Cancer Genomics CaldasCarlos Co-Chair United Kingdom Epigenetic dysregulation and cancer evolution ScaffidiPaola Speaker Italy Proffered Paper: Integrative multi-omic approach to identify patterns of immune selection in primary breast tumours EACR25-0508 EACR25-0508 MonterdeBeatriz Presenter United Kingdom EMBO Young Investigator Lecture: Cancer aneuploidy - From evolutionary pressures to cellular vulnerabilities (REMOTE PRESENTATION) Ben-DavidUri Speaker Israel Proffered Paper: Genetic background sets the trajectory of cancer evolution EACR25-2424 EACR25-2424 AitkenJSarah Presenter United States Title to be announced TurajlicSamra Speaker United Kingdom Auditorium I			Joint EACR - EMBO Symposium: Advanced in vitro Models ChumduriCindrilla Co-Chair Denmark BernardsRene Co-Chair Netherlands Cell plasticity in human colon and cancer SnippertHugo Speaker Netherlands Proffered Paper: Contact-based transfer of thymidylate promotes collective tumor growth EACR25-0343 EACR25-0343 SiddiquiMohammad Aarif Presenter Denmark Development of advanced immunotherapies using human 3D-bioprinted cancer avatars Satchi-FainaroRonit Speaker Israel Proffered Paper: Deconvolution of heterogeneous 3D mammary spheroid dynamics using Oblique Plane Microscopy (OPM) EACR25-2342 EACR25-2342 ModerauNina Presenter United Kingdom Deciphering the role of infection and diet in driving early carcinogenic events using advanced organoid models and omics ChumduriCindrilla Speaker Denmark Auditorium II			Joint EACR - ASPIC Symposium: Cancer Therapy Resistance AmbrogioChiara Co-Chair Italy ParedesJoana Co-Chair Portugal Studying melanoma therapy resistance one cell at the time MarineJean-Christophe Speaker Belgium Proffered Paper: Dynamics and chemotherapy response of single cell-derived human breast cancer clones EACR25-0507 EACR25-0507 KronheimRachaelSarah Presenter Canada The role of RANK signaling in breast cancer biology and response to therapy CasimiroSandra Speaker Portugal Proffered Paper: Unveiling the impact of intratumoral microbiota in the treatment efficacy of soft tissue sarcoma EACR25-0716 EACR25-0716 TiraboschiLuca Presenter Italy Mechanism of response and resistance to RAS inhibition in solid tumors MisaleSandra Speaker United States Auditorium VI+VII			Symposium: Tumour Dormancy BoitorAlexandra Co-Chair United Kingdom Luisa CorreiaAna Co-Chair Portugal Unravelling mechanisms of ER+ Breast cancer dormancy GomisRoger Speaker Spain Proffered Paper: Translational Reprogramming Drives Immune Evasion in Melanoma Persister Cells Through MIF Secretion EACR25-2481 EACR25-2481 SoumoyLaura Presenter France What makes a tissue favorable or not to metastasis? Luisa CorreiaAna Speaker Portugal Proffered Paper: Neuroblastoma metastatic cells adopt an embryonic diapause-like state in the fetal bone marrow driven by mTOR activity EACR25-0988 EACR25-0988 Castillo FerrerCamila Presenter France How host niche variations regulate disseminated cancer cell dormancy and awakening Aguirre-GhisoJulio A. Speaker United States Auditorium VIII
13:15 15:15	Lunch Break / Exhibition / Poster Viewing Poster and Exhibition Hall
13:30 14:15	Akoya Biosciences, Inc.: Scaling Immuno-Oncology Research with IO60: The Fastest UltraHigh-Plex Spatial Proteomics Panel Title TBC Ivan Masetto Industry Speaker Title TBC HunterKelly Industry Speaker United Kingdom Titel TBC TissotStéphanie Industry Speaker Switzerland Titel TBC TissotStéphanie Industry Speaker Switzerland Titel TBC TissotStéphanie Industry Speaker Switzerland Auditorium II				Illumina: Unlocking the Power of Single-Cell and Spatial Multiomics for Cancer Research Introducing Illumina Single Cell and Spatial Technology Scalable single-cell RNA profiling of pooled CRISPR screens discloses novel biology of cancer and T cells Van MinselPaulien Industry Speaker Belgium Cell Altasing Human Intestine using Illumina Spatial Technology ZhuChenchen Industry Speaker United States Illumina Connected Multiomics ScmidJoachim Industry Speaker Germany Auditorium VI+VII				QIAGEN: TCR Repertoires of Tumor-Infiltrating γδ1 T Cells Reveal PD-1–Modulated Reactivity TCR Repertoires of Tumor-Infiltrating γδ1 T Cells Reveal PD-1–Modulated Reactivity MikulakJoanna Industry Speaker Italy Auditorium VIII
13:30 14:15	Career Discovery Session 2A (open to EACR Early Career & Student Members, pre-registration required) Carracedo PerezArkaitz Coordinator Spain OricchioElisa Coordinator Switzerland TABLE 1: How to build your own network RisquesRosana Moderator United States TABLE 2: Leadership: Experience in combining research with the direction of a research institute BardelliAlberto Moderator Italy TABLE 3: Leadership: Experience as a team leader and a research center science director MarineJean-Christophe Moderator Belgium TABLE 4: Life of a scientist between research and hospital SomervailleTim Moderator United Kingdom TABLE 5: How to make your research impactful and transferable to the clinic GomisRoger Moderator Spain TABLE 6: How to build a successful lab environment WestermarckJukka Moderator Finland TABLE 7: How do you know when you are ready to start your own lab? TurajlicSamra Moderator United Kingdom TABLE 8: Challenges of setting up a new lab and establishing yourself as a PI in your home country after years abroad Luisa CorreiaAna Moderator Portugal TABLE 9: The challenges of starting your own lab VenkateshHumsa Moderator United States TABLE 10: ERC funding opportunities for starting or establishing a research group in the EU or Associated Countries CaraffiniVeronica Moderator Career Discovery Area
14:25 15:15	Career Discovery Session 2B (open to EACR Early Career & Student Members, pre-registration required) Carracedo PerezArkaitz Coordinator Spain OricchioElisa Coordinator Switzerland TABLE 1: A career at the intersection between cell biology and oncology RegenbergBirgitte Moderator Denmark TABLE 2: Navigating a career in Academia and Industry PaganiMassimiliano Moderator Italy TABLE 3: Challenges of being a clinician scientist: Successfully balancing clinical and academic duties TaberneroJosep Moderator Spain TABLE 4: From fundamental science to translational impact de VisserKarin E. Moderator Netherlands TABLE 7: Current challenges in academia: tips to survive Aguirre-GhisoJulio A. Moderator United States TABLE 8: The challenges of starting your own lab MisaleSandra Moderator United States TABLE 9: Leadership: Experience of a former EACR president BernardsRene Moderator Netherlands TABLE 10: From performing research to supporting researchers: transitioning from academia to scientific administration CaraffiniVeronica Moderator Career Discovery Area
14:30 15:15	Olink, part of Thermo Fisher Scientific: Plasma Proteomics: Driving a New Era for Cancer Research and Precision Medicine RUCEVICGuyonnetMarijana Industry Moderator/ Chair Sweden Olink Proteomics: Accelerating progress in cancer research and the path to therapeutics RUCEVICGuyonnetMarijana Industry Speaker Sweden Deep plasma proteomics identifies and validates an eight-protein biomarker panel for ovarian cancer EnrothStefan Industry Speaker Sweden Liquid biopsy: Plasma proteomics to identify novel biomarkers ItalianoAntoine Industry Speaker France Questions and Answers Auditorium II				NVision Imaging Technologies: Hyperpolarized MRI Agents: Visualize Cancer Metabolism - As It Happens Introduction to C13 Hyperpolarization BennettSimon Industry Speaker Germany Applications for imaging and measuring metabolism in vivo BennettSimon Industry Speaker Germany Q&A Auditorium VI+VII				Oxford Nanopore Technologies: Deciphering Cancer Evolution and Progression with Multiomic Single Cell Insights Juarez Eleonora Industry Moderator/ Chair United States Unlocking Novel Cancer Biology with Multiomic Insights, Introduction by Chair/ Moderator Juarez Eleonora Industry Moderator/ Chair United States Bridging genotype and phenotype through single-cell and single-molecule multi-omics HarbersLuuk Industry Speaker Belgium Tumour heterogeneity and clonal selection of ecDNA at single-cell level Deleuran Hendriksen Josephine Industry Speaker Denmark Auditorium VIII
15:20 16:55	Symposium: AI Tools in Cancer Research CaldasCarlos Co-Chair United Kingdom JacquemetGuillaume Co-Chair Finland Agent-Based Modelling of Gene Networks the tumour microenvironment ecosytem BuffaMeteoraFrancesca Speaker United Kingdom Proffered Paper: High-throughput drug screening in breast cancer PDTCs enables clinically relevant drug discovery for personalised medicine. EACR25-1681 EACR25-1681 MasinaRiccardo Presenter United Kingdom The power of many: Unlocking treatment response patterns through single-cell meta-analysis (REMOTE PRESENTATION) AranDvir Speaker Israel Proffered Paper: Spatial and multi-omic profiling of HGSC to identify immune vulnerabilities for precision immunotherapy EACR25-0439 EACR25-0439 ShabanovaAleksandra Presenter Finland Harnessing computational tools to understanding somatic evolution in cancer McGranahanNicholas Speaker United Kingdom Auditorium I			Symposium: Prevention and Early Detection LimEmilia Co-Chair Canada SoengasMarisol S. Co-Chair Spain Polygenic risk models and prevention in breast and ovarian cancer PharoahPaul Speaker United States Proffered Paper: Multi-omic spatial analysis reveals reshaping of tumour-immune dynamics at the transition to invasive colorectal cancer EACR25-1604 EACR25-1604 BakerAnn-Marie Presenter United Kingdom Mechanisms of Lung Cancer Promotion HillWilliam Speaker United Kingdom Proffered Paper: Tumour genotype shapes blood biomarker expression for use in pancreatic cancer detection and diagnosis EACR25-0817 EACR25-0817 CanelMarta Presenter United Kingdom Investigating the impact of environmental exposures LimEmilia Speaker Canada Auditorium II			Symposium: DNA Repair and Immunosurveillance BardelliAlberto Co-Chair Italy DiazLuis Alberto Co-Chair United States DNA repair-dependent immunogenic liabilities in colorectal cancer: the opportunity comes from the errors GermanoGiovanni Speaker Italy Proffered Paper: Exploit Neutrophil Heterogeneity to induce Synthetic Lethality in Breast Cancer EACR25-0256 EACR25-0256 CalcinottoArianna Presenter Switzerland Immunoprevention in Lynch Syndrome DiazLuis Alberto Speaker United States Proffered Paper: Intratumoral STING pathway activation enhances anti-tumor immune responses and therapeutic efficacy of ATR inhibition. EACR25-0468 EACR25-0468 SenTriparna Presenter United States Know Your Enemy: Unraveling the Gene Regulatory Networks of Tumor-Infiltrating CD4+ Regulatory T Cells PaganiMassimiliano Speaker Italy Auditorium VI+VII			Symposium: EC DNA DiveCaroline Co-Chair United Kingdom dos Santos DiasMatheus Co-Chair The Netherlands Extrachromosomal DNA (ecDNA): Cancer’s Dynamic Circular Genome MischelPaul Salomon Speaker United States Proffered Paper: Heterogeneous oncogene dosage driven by extrachromosomal DNA determines neuroblastoma response to therapy EACR25-0364 EACR25-0364 MontuoriGiulia Presenter Germany Functional Role of Extrachromosomal Circular DNA in Colorectal, Renal and Bladder Cancers RegenbergBirgitte Speaker Denmark Proffered Paper: Investigating the impact of extrachromosomal DNA amplification on cell fate decisions and therapy resistance EACR25-2262 EACR25-2262 SchmargonRachel Presenter Germany A general strategy to model ecDNA-mediated focal amplifications in cells and in mice VenturaAndrea Speaker Auditorium VIII
16:55 17:30	Coffee Break / Exhibition / Industry Spotlight Poster and Exhibition Hall
17:15 17:30	Cellecta Inc. Industry Spotlight: TCR/BCR Repertoire Profiling and other Approaches for Drug Target and Biomarker Discovery ChenchikAlex Industry Speaker United States A practical guide for adaptive immune receptor repertoire profiling and the characterization of antigen-induced clonotypes with applications in cancer, vaccine development, and autoimmunity ChenchikAlex Industry Speaker United States Spotlight Theatre
17:30 18:15	Plenary Session - From Bench to Bedside and Back BardelliAlberto Chair Italy BernardsRene Co-Chair Netherlands Clinical findings in preclinical perspective BardelliAlberto Speaker Italy BernardsRene Speaker Netherlands Introduction on PFS and OS of the BREAKWATER study (1st line) TaberneroJosep Speaker Spain Clinical Development Saoudi GonzálezNadia Speaker Italy Auditorium I
18:15 18:40	Posters in the Spotlight - Wednesday dos Santos DiasMatheus Moderator The Netherlands Dissecting ovarian cancer cellular responses to radioimmunotherapy with β- particle and ultra-short range conversion and Auger electron-emitting radionuclides. (EACR25-0133) P-552 EACR25-0133 GrzmilMichal Presenter Switzerland Pan-cancer analysis of successive whole genome duplication in the 100,000 Genomes Project (EACR25-0555) P-746 EACR25-0555 SmythEvie Presenter Ireland COX-2/PGE2 Activity in Cancer Cells: A Key Driver of Metastasis via Immune Escape (EACR25-0743) P-773 EACR25-0743 RussoMassimo Presenter United Kingdom Depleting tumour-infiltrating Tregs to enhance the efficacy of KRAS-mutant targeted therapies in lung cancer (EACR25-1513) P-790 EACR25-1513 de CastroAndrea Presenter United Kingdom Cytotoxic ILC-1 cells determine outcome of PD-(L)1 blockade in microsatellite instable cancers (EACR25-2039) P-522 EACR25-2039 Van RoyenPaula Presenter Netherlands Spotlight Theatre
18:40 20:00	Poster Defence Session - Wednesday
10:45 20:00	Poster Session Wednesday Poster and Exhibition Hall						Poster Session Wednesday - LATE ABSTRACTS Poster and Exhibition Hall